Bidirectional regulation of glycoprotein nonmetastatic melanoma protein B by beta-glucocerebrosidase deficiency in GBA1 isogenic dopaminergic neurons from a patient with Gaucher disease and parkinsonism.
Chen C, Ma C, Sam R, Lichtenberg J, Chen T, Hao Y, Li Z, Kowal I, Andersh K, Qi YA, Perez G, Hertz E, Li Y, Williams D, Henderson MJ, Park M, Jiang X, Jerez PA, Blauwendraat C, Sidransky E, Chen Y
bioRxiv [Preprint]. 2025 Jun 25:2025.06.23.661126. doi: 10.1101/2025.06.23.661126.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 247977 | pC13N-TMEM192-mGFP-3xHA-T2A-TOM20-mTagBFP-TwinStrep | Knock-in vector to express TMEM192-mGFP-3xHA and TOM20-mTagBFP-twinStrep from CLYBL site |
| 247978 | pDONOR-tagBFP-PSM-EGFP-GBA1 | HDR donor vector to revert GBA1 N370S to WT |
| 247979 | pDONOR-tagBFP-PSM-dTOMATO-GBA1 | HDR donor vector to revert GBA1 N370S to WT |
| 247980 | pLEX307-HiBiT-GPNMB-V5 | Lentivirus vector to express HiBiT-GPNMB-V5 |