TEADlight, a bright dynamic reporter for live detection of YAP/TAZ-TEAD signaling.
Morin V, Le Toquin Y, Tepordei D, Marcelle C, Delaune E
Dev Biol. 2025 Sep;525:194-205. doi: 10.1016/j.ydbio.2025.06.007. Epub 2025 Jun 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 248043 | Teadlight-T2-8xGTIIc-IVS-Syn21-AchillesNlsPest-p10 | Dynamic fluorescent YAP/TAZ-TEAD transcriptional reporter (flanked with Tol2 sites for transgenesis) |
| 248044 | CAG-mKate2-NLS | Encodes nuclear mKate2 fluorescent protein, under control of the CAG promoter. The construct is flanked by Tol2 sites for transgenesis. |
| 248046 | CAG-YAP-5SA | Encodes onstitutively active YAP1 under the control of the CAG promoter. The construct is flanked by Tol2 sites for transgenesis. |
| 248048 | CAG-YAP1∆TA | Encodes a YAP1 mutant lacking the transactivation domain, under the control of the CAG promoter. The construct is flanked by Tol2 sites for transgenesis. |