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Distinguishing Pseudotransduction and True Transduction Enables Characterization and Bioengineering of Extracellular Vesicle-Adeno-Associated Virus Vectors.

Boucher JD, Stranford DM, Edelstein HI, Tullman-Ercek D, Kamat NP, Leonard JN
J Extracell Vesicles. 2026 Apr;15(4):e70258. doi: 10.1002/jev2.70258. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
252770pJB035 pAAV CMV LumiScarletAn AAV vector that expresses CMV driven LumiScarlet
252771pJB038 pAAV EF1a flox(mCherry)-EGFPAn AAV vector that expresses a Cre-dependent mCherry to eGFP
252772pJB040 pAAV EF1a Nuc-flox(mCherry)-mNeonGreenAn AAV vector that expresses a Cre-dependent nuclear-localized mCherry to mNeonGreen
252773pJB041 (pAAV EF1a flox(mCherry)-mNeonGreenAn AAV vector that expresses a Cre-dependent mCherry to mNeonGreen
252774pHIE822 pCMV Bglobin intron VSVGmut K47Q R354A in pMD2VSV-G mutant with abolished receptor binding, but maintained fusogenic capacity
252775pHIE963 pCCL pSFFV Cre_BC_entry_IRES_PuroR3rd generation lentiviral vector encoding Cre recombinase

Antibodies from Article