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EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity.

Allhorn M, Olsen A, Collin M
BMC Microbiol. 2008 Jan 8;8:3. doi: 10.1186/1471-2180-8-3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
44656pGEXndoS(E235Q)

Antibodies from Article