Superti-Furga Lab Human SLC Knockout Library
(Pooled Library #132552)
The CRISPR knockout library targets the human solute carrier family of proteins. A set of additional 20 essential genes is also targeted as a control set.
lentiCRISPR v2 - Expresses Cas9
|Item||Catalog #||Description||Quantity||Price (USD)|
|Pooled Library||132552||gRNA pooled library||1||$350||Add to Cart|
20 essential genes
Controls120 non-targeting sgRNAs
This library is delivered as suspended DNA in a microcentrifuge tube on blue ice. The tube's contents will not necessarily be frozen. For best results, minimize freeze-thaws.
The Research Empowerment on Solute Carriers (ReSOLUTE) plasmid collection contains codon-optimized human SLCs in Gateway-compatible pENTR vectors and may be a useful resource for researchers using this library.
These pooled libraries were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.
For your Materials & Methods section:Human SLC Knockout Library was a gift from Giulio Superti-Furga (Addgene #132552)
For your References section:A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs. Girardi E, Cesar-Razquin A, Lindinger S, Papakostas K, Konecka J, Hemmerich J, Kickinger S, Kartnig F, Gurtl B, Klavins K, Sedlyarov V, Ingles-Prieto A, Fiume G, Koren A, Lardeau CH, Kumaran Kandasamy R, Kubicek S, Ecker GF, Superti-Furga G. Nat Chem Biol. 2020 Apr;16(4):469-478. doi: 10.1038/s41589-020-0483-3. Epub 2020 Mar 9. PubMed 32152546