We narrowed to 18,031 results for: Mut

1. pBABE-hygro-BAP1-C91S-HA

   Plasmid

   #154021

   Purpose

   Mammalian Expression of HA-tagged p.C91S Mutant BAP1

   Depositor

   Samuel Peña-Llopis

   Article

   Niersch et al iScience. 2021 Feb 12;24(3):102173. doi:

   Insert

   BAP1 (BAP1 Human)
   

   Use

   Retroviral

   Tags

   Hemagglutinin (HA)

   Expression

   Mammalian

   Mutation

   p.C91S (Missense Mutation, Catalytically Inactive)

   Promoter

   Available Since

   Feb. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCAD54_CAD29_H104A_pvp008

   Plasmid

   #124876

   Purpose

   Expresses hCAD His103Ala mutant in E.coli

   Depositor

   Konrad Buessow

   Article

   Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

   Insert

   cis-aconitate decarboxylase (ACOD1 Human)
   

   Use

   Tags

   StrepTag and TEV site

   Expression

   Bacterial

   Mutation

   mutated His103 to Ala, deleted amino acids 1-3 an…

   Promoter

   T7

   Available Since

   Sept. 16, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCAD108_Arg273His_pCMV6Entry-hIRG1

   Plasmid

   #124878

   Purpose

   Expresses hCAD Arg273His mutant in mammalian cells

   Depositor

   Konrad Buessow

   Article

   Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

   Insert

   cis-aconitate decarboxylase (ACOD1 Human)
   

   Use

   Tags

   myc and FLAG tags

   Expression

   Mammalian

   Mutation

   mutated Arg273 to His

   Promoter

   CMV

   Available Since

   Sept. 23, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCAD96_hIRG1_4-461_pvp008

   Plasmid

   #124874

   Purpose

   Expresses hCAD Asn152Ser mutant in E.coli

   Depositor

   Konrad Buessow

   Article

   Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

   Insert

   cis-aconitate decarboxylase (ACOD1 Human)
   

   Use

   Tags

   StrepTag and TEV site

   Expression

   Bacterial

   Mutation

   mutated Asn152 to Ser, deleted amino acids 1-3 an…

   Promoter

   T7

   Available Since

   Oct. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. HR700_HA2TP53_Ex5

   Plasmid

   #228860

   Purpose

   Backbone for generation of donor vectors for CRISPR/Cas9 mediated Saturation Genome Editing (SGE) of TP53 Exon 5

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Type

   Empty backbone

   Use

   CRISPR and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 4, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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6. HR700_HA2TP53_Ex6

   Plasmid

   #228861

   Purpose

   Backbone for generation of donor vectors for CRISPR/Cas9 mediated Saturation Genome Editing (SGE) of TP53 Exon 6

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Type

   Empty backbone

   Use

   CRISPR and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 4, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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7. HR700_HA2TP53_Ex7

   Plasmid

   #228862

   Purpose

   Backbone for generation of donor vectors for CRISPR/Cas9 mediated Saturation Genome Editing (SGE) of TP53 Exon 7

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Type

   Empty backbone

   Use

   CRISPR and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 4, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. HR700_HA2TP53_Ex8

   Plasmid

   #228863

   Purpose

   Backbone for generation of donor vectors for CRISPR/Cas9 mediated Saturation Genome Editing (SGE) of TP53 Exon 8

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Type

   Empty backbone

   Use

   CRISPR and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 4, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

9. pcDNA3.1/CALR ins5 (del18-197)-FLAG

   Plasmid

   #204539

   Purpose

   Mammalian expression of human CALR ins5 (del18-197)-FLAG

   Depositor

   Norio Komatsu

   Article

   Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

   Insert

   CALR ins5 (del18-197)-FLAG (CALR Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   ins5 (del18-197)

   Promoter

   Available Since

   Sept. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA3.1/CALR ins5 (del198-430)-FLAG

    Plasmid

    #204538

    Purpose

    Mammalian expression of human CALR ins5 (del198-430)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del198-430)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del198-430)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3.1/CALR ins5 (del367-430)-FLAG

    Plasmid

    #204536

    Purpose

    Mammalian expression of human CALR ins5 (del367-430)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del367-430)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del367-430)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pcDNA3.1/CALR ins5 (del309-430)-FLAG

    Plasmid

    #204537

    Purpose

    Mammalian expression of human CALR ins5 (del309-430)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del309-430)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del309-430)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1/CALR ins5 (del1-308)-FLAG

    Plasmid

    #204535

    Purpose

    Mammalian expression of human CALR ins5 (del1-308)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del1-308)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del1-308)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3.1/CALR ins5 (del198-308)-FLAG

    Plasmid

    #204540

    Purpose

    Mammalian expression of human CALR ins5 (del198-308)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del198-308)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del198-308)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.1/CALR ins5 (del1-197)-FLAG

    Plasmid

    #204534

    Purpose

    Mammalian expression of human CALR ins5 (del1-197)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del1-197)-FLAG (CALR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    ins5 (del1-197)

    Promoter

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Donor-CD55-NeoR

    Plasmid

    #153551

    Purpose

    Used as a donor vector for the targeted knock-in of a CD55 mutation. This plasmid carries a neomycin resistance gene cassette

    Depositor

    Hiroyuki Konishi

    Article

    Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7

    Insert

    mutant CD55 (a 1415-bp fragment from intron 3, exon 4 and intron 4, with a 1-bp mutation in exon 4), divided into 5' and 3' arms
    

    Use

    AAV and Cre/Lox; Donor plasmid/targeting vector

    Tags

    N/A

    Expression

    Mutation

    a 1-bp mutation in exon 4

    Promoter

    No promoter

    Available Since

    March 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. Donor-PIGA-NeoR

    Plasmid

    #153549

    Purpose

    Used as a donor vector for the targeted knock-in of a PIGA mutation. This plasmid carries a neomycin resistance gene cassette

    Depositor

    Hiroyuki Konishi

    Article

    Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7

    Insert

    mutant PIGA (a 1,991-bp fragment from intron 5 and exon 6 with a 3-bp mutation in exon 6), divided into 5' and 3' arms
    

    Use

    AAV and Cre/Lox; Donor plasmid/targeting vector

    Tags

    N/A

    Expression

    Mutation

    a 3-bp mutation in exon 6

    Promoter

    No promoter

    Available Since

    Dec. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCAD100_hIRG1_4-461_pvp008

    Plasmid

    #124875

    Purpose

    Expresses hCAD Arg273His mutant in E.coli

    Depositor

    Konrad Buessow

    Article

    Chen et al Proc Natl Acad Sci U S A. 2019 Sep 23. p

    Insert

    cis-aconitate decarboxylase (ACOD1 Human)
    

    Use

    Tags

    StrepTag and TEV site

    Expression

    Bacterial

    Mutation

    mutated Arg273 to His, deleted amino acids 1-3 an…

    Promoter

    T7

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. ORAI1-YFP V107M-L273D-L276D

    Plasmid

    #114183

    Purpose

    ORAI1 channel with C-terminal YFP, carrying the constitutively activating mutation V107M from TAM, and the mutations L273D-L276D leading to a deficiency in STIM1-mediated gating.

    Depositor

    Nicolas Demaurex

    Article

    Bulla et al J Physiol. 2018 Nov 1. doi: 10.1113/JP27

    Insert

    ORAI1-YFP V107M-L273D-L276D (ORAI1 Human)
    

    Use

    Tags

    YFP

    Expression

    Mammalian

    Mutation

    V107M/L273D/L276D

    Promoter

    Available Since

    Nov. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. ORAI1-YFP T184M-L273D-L276D

    Plasmid

    #114184

    Purpose

    ORAI1 channel with C-terminal YFP, carrying the activating mutation T184M from TAM, and the mutations L273D-L276D leading to a deficiency in STIM1-mediated gating.

    Depositor

    Nicolas Demaurex

    Article

    Bulla et al J Physiol. 2018 Nov 1. doi: 10.1113/JP27

    Insert

    ORAI1-YFP T184M-L273D-L276D (ORAI1 Human)
    

    Use

    Tags

    YFP

    Expression

    Mammalian

    Mutation

    T184M/L273D/L276D

    Promoter

    Available Since

    Nov. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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