We narrowed to 12,735 results for: icos

1. pS97splitRBP_S1-Enz

   Plasmid

   #183767

   Purpose

   Expresses SHIP1-Enzyme domain flanked by RBP

   Depositor

   William Kerr

   Article

   Sudan et al Front Immunol. 2022 May 4;13:830961. doi

   Insert

   SHIP1 (INPP5D Human)
   

   Use

   Tags

   6HIS, RBP (C-terminal) w/HRV3C cleavage site, and…

   Expression

   Bacterial

   Mutation

   includes aa N393 to aa L864 only

   Promoter

   T7lac

   Available since

   May 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pET24TEV-tSHIP2

   Plasmid

   #183771

   Purpose

   Expresses C-terminal truncated SHIP2 (tSHIP2) with C-terminal TEV and 6HIS tags from pET24 backbone

   Depositor

   William Kerr

   Article

   Sudan et al Front Immunol. 2022 May 4;13:830961. doi

   Insert

   SHIP2 (INPPL1 Human)
   

   Use

   Tags

   6HIS and Tobacco Etch Virus (TEV) Cleavage site

   Expression

   Bacterial

   Mutation

   includes aa18 to aa985 only

   Promoter

   T7 lac

   Available since

   May 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV9-hSyn-iDianiSnFR_PM

   Plasmid

   #177759

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iDianiSnFR_PM
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Feb. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV9-hSyn-iDianiSnFR_ER

   Plasmid

   #177758

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iDianiSnFR_ER
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Feb. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV9-hSyn-iCyt_F_SnFR_PM

   Plasmid

   #177755

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iCyt_F_SnFR_PM
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Feb. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pAAV9-hSyn-iCytSnFR_PM

   Plasmid

   #177753

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iCytSnFR_PM
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Feb. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pAAV9-hSyn-iCytSnFR_ER

   Plasmid

   #177752

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iCytSnFR_ER
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Feb. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV9-hSyn iCyt_BrEt_SnFR_ER

   Plasmid

   #177756

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn iCyt_BrEt_SnFR_ER
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Dec. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pAAV9-hSyn-iCyt_F_SnFR_ER

   Plasmid

   #177754

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al eLife. 2022 Jan 4;11. pii: 74648. doi: 1

   Insert

   pAAV9-hSyn-iCyt_F_SnFR_ER
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available since

   Dec. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCMV6-Entry IL36RN R48W

    Plasmid

    #58324

    Purpose

    entry vector for human IL36RN R48W mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    R48W: c.142C>T, p.Arg48Trp

    Promoter

    CMV

    Available since

    July 30, 2014

    Availability

    Academic Institutions and Nonprofits only

11. pCMV6-Entry IL36RN P76L

    Plasmid

    #58322

    Purpose

    entry vector for human IL36RN P76L mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    P76L: c.227C>T,p.Pro76Leu​

    Promoter

    CMV

    Available since

    July 30, 2014

    Availability

    Academic Institutions and Nonprofits only

12. pCMV6-Entry IL36RN Κ35R

    Plasmid

    #58320

    Purpose

    entry vector for human IL36RN K35R mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    Κ35R: c.104A>G, p.Lys35Arg​

    Promoter

    CMV

    Available since

    July 25, 2014

    Availability

    Academic Institutions and Nonprofits only

13. pCMV5b HA Irx5 deltaIrot

    Plasmid

    #24995

    Depositor

    Benoit Bruneau

    Article

    Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

    Insert

    Irx5 (Irx5 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Deletion of Iro box (aa 314-327), 19 aa upstream …

    Promoter

    Available since

    Aug. 2, 2010

    Availability

    Academic Institutions and Nonprofits only

14. pCMV5b HA Irx5 deltaC

    Plasmid

    #24996

    Depositor

    Benoit Bruneau

    Article

    Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

    Insert

    Irx5 (Irx5 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Deletes everything after Hox Domain (aa 112-177).…

    Promoter

    Available since

    Aug. 2, 2010

    Availability

    Academic Institutions and Nonprofits only

15. pNK3071

    Plasmid

    #219755

    Purpose

    MoClo-compatible Level P vector for improved autonomous bioluminescence in plants encoding kanamycin resistance cassette, mcitHispS, NpgA, nnH3H_v2, nnLuz_v4 and nnCPH.

    Depositor

    Alexander Mishin

    Article

    Shakhova et al Nat Methods. 2024 Mar;21(3):406-410. doi

    Insert

    mcitHispS, NpgA, nnH3H_v2, nnLuz_v4 and nnCPH
    

    Use

    Tags

    Expression

    Plant

    Mutation

    Promoter

    Available since

    Oct. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. Ma-pREP

    Plasmid

    #197571

    Purpose

    Positive selection plasmid for selecting ncAA-encoding Methanomethylophilus alvus Pyl-RS mutants. Expresses TAG-codon interrupted chloramphenicol resistance cassette and M. alvus Pyl-tRNA(6). p15a ori

    Depositor

    Ryan Mehl

    Article

    Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

    Inserts

    Chloramphenicol resistance gene - 111TAG
    T7 polymerase -TAG
    GFPuv
    M. alvus Pyl-tRNA(6)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    111TAG and 8TAG/112TAG

    Promoter

    AraC, T7, cat promoter (constitutive), and lpp (c…

    Available since

    April 10, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. Ezh2[FL]-dCas9

    Plasmid

    #100086

    Purpose

    Full-length [FL] mouse Ezh2 fused to N-terminus of dCas9; pCDNA3 vector backbone, mammalian expression

    Depositor

    David Segal

    Article

    O'Geen et al Nucleic Acids Res. 2017 Sep 29;45(17):99

    Insert

    14056 (Ezh2 Mouse)
    

    Use

    CRISPR

    Tags

    3XFLag-NLS-Ezh2[FL]-dCas9-NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Oct. 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. DNMT3A-dCas9

    Plasmid

    #100090

    Purpose

    DNMT3A fused to N-terminus of dCas9; pCDNA3 vector backbone, mammalian expression

    Depositor

    David Segal

    Article

    O'Geen et al Nucleic Acids Res. 2017 Sep 29;45(17):99

    Insert

    DNMT3A (DNMT3A Human)
    

    Use

    CRISPR

    Tags

    3XFLag-NLS-DNMT3A-dCas9-NLS

    Expression

    Mammalian

    Mutation

    includes aa 602-912

    Promoter

    CMV

    Available since

    Oct. 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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19. G9A[SET]-dCas9

    Plasmid

    #100089

    Purpose

    Catalytic domain [SET] of human G9A fused to N-terminus of dCas9; pCDNA3 vector backbone, mammalian expression

    Depositor

    David Segal

    Article

    O'Geen et al Nucleic Acids Res. 2017 Sep 29;45(17):99

    Insert

    G9A (EHMT2 Human)
    

    Use

    CRISPR

    Tags

    3XFLag-NLS-G9A[SET]-dCas9-NLS

    Expression

    Mammalian

    Mutation

    G9A[SET] includes aa 829-1209

    Promoter

    CMV

    Available since

    Oct. 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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20. pYLCRISPR/Cas9P35S-H

    Plasmid

    #66189

    Purpose

    expression of Cas9 in plants, cauliflower mosaic virus 35S promoter (P35S), hygro selection

    Depositor

    Yao-Guang Liu

    Article

    Ma et al Mol Plant. 2015 Apr 24. pii: S1674-2052(

    Insert

    Cas9
    

    Use

    Tags

    Expression

    Plant

    Mutation

    plant-codon optimized with higher GC contents (62…

    Promoter

    cauliflower mosaic virus 35S promoter (P35S)

    Available since

    June 4, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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