We narrowed to 3,403 results for: aaas

1. CHUK gRNA (BRDN0001149372)

   Plasmid

   #77033

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CHUK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CHUK (CHUK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. Stat3 (A662C,N664C,V667L)-pcw107-V5

   Plasmid

   #64611

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   STAT3 (STAT3 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Mutation

   A662C, N664C, V667L

   Promoter

   PGK

   Available Since

   May 12, 2015

   Availability

   Academic Institutions and Nonprofits only

3. pKHH030_sgRB1#1

   Plasmid

   #174144

   Purpose

   Lentiviral vector expressing a sgRNA against the human RB1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   RB1 (RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pKLV2-U6gRNA5(SOX2_v32_7-5)-PGKpuroBFP-W

   Plasmid

   #211987

   Purpose

   Express gRNA against SOX2 with puro and BFP

   Depositor

   Kosuke Yusa

   Article

   Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

   Insert

   sgRNA targeting SOX2 (SOX2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   Human U6 promoter

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. Rgl2-CAAX-pcw107-V5

   Plasmid

   #64641

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   Rgl2 plus C-term KRAS (Kras Mouse)
   

   Use

   Lentiviral

   Tags

   V5

   Mutation

   C-term of Kras

   Promoter

   PGK

   Available Since

   Dec. 3, 2015

   Availability

   Academic Institutions and Nonprofits only

6. Gli2 truncation-pcw107-V5

   Plasmid

   #64626

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   GLI2 (truncation mutant) (GLI2 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Mutation

   truncated

   Promoter

   PGK

   Available Since

   May 12, 2015

   Availability

   Academic Institutions and Nonprofits only

7. shERK1a-mlpx-puro

   Plasmid

   #65228

   Purpose

   encodes a shRNA against ERK1

   Depositor

   Gerardo Ferbeyre

   Article

   Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

   Insert

   shRNA against ERK2 (MAPK1 Human)
   

   Expression

   Mammalian

   Available Since

   Aug. 12, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pBScMXT + Slo1

   Plasmid

   #16194

   Depositor

   Larry Salkoff

   Article

   McCobb et al Am J Physiol. 1995 Sep . 269(3 Pt 2):H76

   Insert

   calcium-activated potassium channel (KCNMA1, Kcnma1 Human, Mouse)
   

   Use

   Xenopus oocyte expression

   Mutation

   N/A

   Available Since

   Jan. 10, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO.1-puro-shWRN2

   Plasmid

   #125782

   Purpose

   constitutive expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. CHUK gRNA (BRDN0001148194)

    Plasmid

    #77035

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CHUK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CHUK (CHUK Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. FGFR1 gRNA (BRDN0001145494)

    Plasmid

    #76067

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGFR1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGFR1 (FGFR1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. AKT3 gRNA (BRDN0001144935)

    Plasmid

    #76218

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AKT3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AKT3 (AKT3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Aug. 16, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. AKT3 gRNA (BRDN0001145071)

    Plasmid

    #76219

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AKT3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AKT3 (AKT3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. AKT3 gRNA (BRDN0001147841)

    Plasmid

    #76220

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AKT3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AKT3 (AKT3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. JNK2 WT O/E (MAPK9)-pcw107-V5

    Plasmid

    #64617

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAPK9 (transcript variant JNK2-a2) (MAPK9 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Mutation

    none

    Promoter

    PGK

    Available Since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

16. CSF1R gRNA (BRDN0001147492)

    Plasmid

    #77037

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CSF1R

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CSF1R (CSF1R Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. FLAG-MKK6 (S207E,T211E)-pcw107

    Plasmid

    #64625

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K6 (MAP2K6 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Mutation

    S207E,T211E

    Promoter

    PGK

    Available Since

    June 10, 2015

    Availability

    Academic Institutions and Nonprofits only

18. myr-FLAG-MEK5-pcw107

    Plasmid

    #64620

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K5 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    Flag and myristoylated

    Promoter

    PGK

    Available Since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

19. Lenti-sgArid2#2/Cre

    Plasmid

    #173576

    Purpose

    Expresses a Arid2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Arid2 (Arid2 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. ERBB3 gRNA (BRDN0001147088)

    Plasmid

    #77481

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ERBB3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ERBB3 (ERBB3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge