We narrowed to 5,114 results for: mcs

1. pXPR_BRD003 UBE2C guide 2

   Plasmid

   #117071

   Purpose

   single guide RNA targeting UBE2C; guide 2

   Depositor

   William Hahn

   Article

   Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

   Insert

   UBCH10 (UBE2C Human)
   

   Use

   CRISPR

   Available Since

   March 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLXI_TRC403 SMARCB1 var 2

   Plasmid

   #111185

   Purpose

   Inducible vector (V5 tagged) with SMARCB1 variant 2

   Depositor

   William Hahn

   Article

   Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

   Insert

   BAF47 (SMARCB1 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Promoter

   TRE

   Available Since

   March 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLXI_TRC401 SMARCB1 var 2

   Plasmid

   #111182

   Purpose

   Inducible vector (untagged) with SMARCB1 variant 2

   Depositor

   William Hahn

   Article

   Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

   Insert

   BAF47 (SMARCB1 Human)
   

   Use

   Lentiviral

   Promoter

   TRE

   Available Since

   March 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCW-codon optimized catalytically inactive PHGDH

   Plasmid

   #154903

   Purpose

   Expresses codon optimized catalytically inactive PHGDH in mammalian cells

   Depositor

   Michael Pacold

   Article

   Ngo et al Cancer Discov. 2020 Sep;10(9):1352-1373.

   Insert

   Phosphoglycerate dehydrogenase (PHGDH Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Three mutations: D175N, R236K, H283A

   Promoter

   TRE

   Available Since

   July 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDONR SMARCB1 var 2

   Plasmid

   #111181

   Purpose

   SMARCB1 variant 2 in pDONR223 backbone

   Depositor

   William Hahn

   Article

   Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

   Insert

   BAF47 (SMARCB1 Human)
   

   Expression

   Bacterial

   Available Since

   March 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. PG13-mCherry

   Plasmid

   #195291

   Purpose

   mCherry reporter containing 13 copies of the p53-binding consensus sequence

   Depositor

   Hideyuki Oguro

   Article

   Pantazis et al Cell Stem Cell. 2022 Dec 1;29(12):1685-1

   Insert

   mCherry
   

   Expression

   Mammalian

   Available Since

   Feb. 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. Green monkey (Chlorocebus sabaeus) sgRNA library

   Pooled Library

   #178284

   Purpose

   Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

   Depositor

   John Doench, David Root

   Article

   Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

   Expression

   Mammalian

   Species

   Chlorocebus sabaeus (african green monkey)

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

8. MXS Chaining Kit

   Plasmid Kit

   #1000000064

   Purpose

   MXS-chaining system for assembly of constructs optimized for synthetic biology applications in mammalian systems. 14 different fluorescent proteins, 10 mammalian promoters/enhancers, 3 polyA signals

   Depositor

   Pierre Neveu

   Available Since

   Aug. 4, 2015

   Availability

   Academic Institutions and Nonprofits only

9. pB-CuR-hSOD1

   Plasmid

   #232477

   Purpose

   The inducible PiggyBac Cumate Switch vector (PBQM812A-1 System Biosciences) expressing human SOD1gene including flag -tag (DYKDDDDK) on the 3' end

   Depositor

   Lukas Trantirek

   Article

   Rynes et al Commun Biol. 2025 Feb 7;8(1):194. doi: 1

   Insert

   Homo sapiens superoxide dismutase 1 (SOD1 Human)
   

   Use

   Transposon system

   Tags

   DYKDDDDK (FLAG-tag)

   Expression

   Mammalian

   Promoter

   CMV-CuO

   Available Since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAV pCAG-FLEX-EGFP-WPRE

    Plasmid

    #51502

    Purpose

    Can be used to generate AAV virus that will express EGFP in the presence of Cre

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Has Service

    AAV Retrograde, AAV1, AAV2, AAV5, AAV8, and AAV9

    Insert

    EGFP
    

    Use

    AAV

    Promoter

    CAG

    Available Since

    Aug. 29, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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11. pB-TR-hSOD1

    Plasmid

    #232478

    Purpose

    Tetracycline inducible PiggyBac vector expressing human SOD1gene including flag-tag (DYKDDDDK) on the 3' end

    Depositor

    Lukas Trantirek

    Article

    Rynes et al Commun Biol. 2025 Feb 7;8(1):194. doi: 1

    Insert

    Homo sapiens superoxide dismutase 1 (SOD1 Human)
    

    Use

    Transposon system

    Tags

    DYKDDDDK (FLAG-tag)

    Expression

    Mammalian

    Promoter

    CMV-TetO

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. AAV phSyn1-RSR-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65429

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Dre and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available Since

    July 17, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV phSyn1(S)-FLEX-tdTomato-WPRE

    Plasmid

    #51505

    Purpose

    Can be used to generate AAV virus that will express tdTomato in the presence of Cre in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Insert

    tdTomato
    

    Use

    AAV

    Promoter

    phSyn1

    Available Since

    May 1, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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14. AAV phSyn1(S)-FLEX-EGFP-WPRE

    Plasmid

    #51504

    Purpose

    Can be used to generate AAV virus that will express EGFP in the presence of Cre in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Insert

    EGFP
    

    Use

    AAV

    Promoter

    phSyn1

    Available Since

    May 1, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV phSyn1-FSF-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65454

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Flp and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available Since

    July 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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16. AAV-KrasG12D/sgKras/Cre

    Plasmid

    #99851

    Purpose

    Expresses Cre-recombinase, a barcoded HDR template to introduce a G12D mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

    Depositor

    Monte Winslow

    Article

    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

    Insert

    Kras (Kras Mouse)
    

    Use

    AAV and Cre/Lox

    Expression

    Mammalian

    Mutation

    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

    Available Since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. AAV-KrasG12C/sgKras/Cre

    Plasmid

    #99850

    Purpose

    Expresses Cre-recombinase, a barcoded HDR template to introduce a G12C mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

    Depositor

    Monte Winslow

    Article

    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

    Insert

    Kras (Kras Mouse)
    

    Use

    AAV and Cre/Lox

    Expression

    Mammalian

    Mutation

    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

    Available Since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. AAV-KrasG12V/sgKras/Cre

    Plasmid

    #99854

    Purpose

    Expresses Cre-recombinase, a barcoded HDR template to introduce a G12V mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

    Depositor

    Monte Winslow

    Article

    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

    Insert

    Kras (Kras Mouse)
    

    Use

    AAV and Cre/Lox

    Expression

    Mammalian

    Mutation

    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

    Available Since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pcDNA5-FRT/TO-V5-SHLD3

    Plasmid

    #114124

    Purpose

    Expresses N-terminally tagged V5-SHLD3 in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD3 (SHLD3 Human)
    

    Use

    Genomic integration, tetracycline inducible

    Tags

    V5

    Expression

    Mammalian

    Promoter

    CMV/TetO2

    Available Since

    Aug. 23, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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20. AAV-KrasG13C/sgKras/Cre

    Plasmid

    #99856

    Purpose

    Expresses Cre-recombinase, a barcoded HDR template to introduce a G13C mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

    Depositor

    Monte Winslow

    Article

    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

    Insert

    Kras (Kras Mouse)
    

    Use

    AAV and Cre/Lox

    Expression

    Mammalian

    Mutation

    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

    Available Since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge