We narrowed to 24,902 results for: Spr

1. SGK1 gRNA (BRDN0001146486)

   Plasmid

   #77459

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human SGK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   SGK1 (SGK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. SGK1 gRNA (BRDN0001145161)

   Plasmid

   #77460

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human SGK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   SGK1 (SGK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. ICK gRNA (BRDN0001146785)

   Plasmid

   #77412

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ICK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ICK
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. ICK gRNA (BRDN0001148893)

   Plasmid

   #77413

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ICK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ICK
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. ICK gRNA (BRDN0001146903)

   Plasmid

   #77414

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ICK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ICK
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. SH3BP4 gRNA (BRDN0001149529)

   Plasmid

   #78087

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human SH3BP4

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   SH3BP4 (SH3BP4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. SH3BP4 gRNA (BRDN0001487091)

   Plasmid

   #78089

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human SH3BP4

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   SH3BP4 (SH3BP4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. SpG_ATH51-IP

   Plasmid

   #242074

   Purpose

   Expresses Cas9-SpG_ATH51 in mammalian cells

   Depositor

   Tobias Cantz

   Article

   Eggenschwiler et al Nucleic Acids Res. 2025 Aug 11;53(15):gk

   Insert

   SpG_ATH51
   

   Use

   CRISPR

   Expression

   Mammalian

   Mutation

   ectopic insertion of 7 amino acids of PID turn-he…

   Available Since

   Oct. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. TRE3G-ZIM3-Cas9-P2A-GFP

   Plasmid

   #239605

   Purpose

   Doxycycline inducible CRISPRgenee construct

   Depositor

   Philipp Rathert

   Article

   Stadager et al Cell Rep Methods. 2025 Jun 16;5(6):10107

   Insert

   ZIM3 KRAB domain (ZIM3 )
   

   Use

   CRISPR and Lentiviral

   Promoter

   TRE3G

   Available Since

   Sept. 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. EF1as-ZIM3-Cas9-P2A-GFP

    Plasmid

    #239603

    Purpose

    Constitutive active CRISPRgenee construct

    Depositor

    Philipp Rathert

    Article

    Stadager et al Cell Rep Methods. 2025 Jun 16;5(6):10107

    Insert

    ZIM3 KRAB domain (ZIM3 )
    

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pKMW121_WT-Cas9_U6-entry

    Plasmid

    #244818

    Purpose

    Mammalian expression of WT Cas9 with Golden Gate-compatible sgRNA spacer cassette

    Depositor

    Jennifer Doudna

    Article

    Shi et al Mol Cell. 2025 May 1;85(9):1730-1742.e9.

    Insert

    SpyCas9 (WT)
    

    Use

    CRISPR

    Tags

    3xFLAG-SV40 NLS and Nucleoplasmin NLS

    Expression

    Mammalian

    Promoter

    CAG, U6

    Available Since

    Sept. 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pPB9v2

    Plasmid

    #210029

    Purpose

    Contains cloning site for molecularly-tagged Cas9 gRNA constructs, inducible Cas9, rtTA-T2A-puro

    Depositor

    Michael Talkowski

    Article

    Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

    Inserts

    Cas9
    rtta-T2A-puro
    

    Use

    CRISPR

    Tags

    SV40 NLS and nucleoplasmin NLS

    Expression

    Mammalian

    Promoter

    EF-1α and TRE3G

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pPB9P2

    Plasmid

    #210030

    Purpose

    Contains PE2 prime editing gRNA cloning site, inducible prime editor 2, rtTA-T2A-puro

    Depositor

    Michael Talkowski

    Article

    Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

    Inserts

    prime editor 2
    rtta-T2A-puro
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Promoter

    EF-1α and TRE3G

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pPB758

    Plasmid

    #210033

    Purpose

    Contains inducible Cas7-P2A-Cas5-T2A-Cas8, rtTA-T2A-puro

    Depositor

    Michael Talkowski

    Article

    Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

    Inserts

    Cas7-P2A-Cas5-T2A-Cas8
    rtta-T2A-puro
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Promoter

    EF-1α and TRE3G

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pCMV-eA3A-BE5-(NG)-PX458-EGFP

    Plasmid

    #229687

    Purpose

    CRISPR CBE plasmid (C to T edits): eA3A-BE5-NG engineered to include the sgRNA cloning backbone from PX458 and EGFP. Includes BbsI sites for sgRNA cloning downstream of U6 promoter.

    Depositor

    Deborah Marsh

    Article

    Dickson et al Hum Mol Genet. 2023 Jun 27:ddad105. doi:

    Type

    Empty backbone

    Use

    CRISPR

    Tags

    EGFP

    Expression

    Mammalian

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCon-IFl_Con-IFr

    Plasmid

    #192209

    Purpose

    Consensus I-F CRISPR Leader and a CRISPR locus with two consensus I-F repeats, for integration assays.

    Depositor

    Blake Wiedenheft

    Article

    Santiago-Frangos et al Nat Struct Mol Biol. 2023 Nov;30(11):167

    Insert

    Consensus I-F Leader and Consensus I-F Locus DNA
    

    Expression

    Bacterial

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCon-IFl_Con-IEr

    Plasmid

    #192210

    Purpose

    Consensus I-F CRISPR Leader and a CRISPR locus with two consensus I-E repeats, for integration assays.

    Depositor

    Blake Wiedenheft

    Article

    Santiago-Frangos et al Nat Struct Mol Biol. 2023 Nov;30(11):167

    Insert

    Consensus I-F Leader and Consensus I-E Locus DNA
    

    Expression

    Bacterial

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pCon-IFl_Con-ICr

    Plasmid

    #192211

    Purpose

    Consensus I-F CRISPR Leader and a CRISPR locus with two consensus I-C repeats, for integration assays.

    Depositor

    Blake Wiedenheft

    Article

    Santiago-Frangos et al Nat Struct Mol Biol. 2023 Nov;30(11):167

    Insert

    Consensus I-F Leader and Consensus I-C Locus DNA
    

    Expression

    Bacterial

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pCon-IFl_Con-IIAr

    Plasmid

    #192212

    Purpose

    Consensus I-F CRISPR Leader and a CRISPR locus with two consensus II-A repeats, for integration assays.

    Depositor

    Blake Wiedenheft

    Article

    Santiago-Frangos et al Nat Struct Mol Biol. 2023 Nov;30(11):167

    Insert

    Consensus I-F Leader and Consensus II-A Locus DNA
    

    Expression

    Bacterial

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCon-IEl_Con-IEr

    Plasmid

    #192213

    Purpose

    Consensus I-E CRISPR Leader and a CRISPR locus with two consensus I-E repeats, for integration assays.

    Depositor

    Blake Wiedenheft

    Article

    Santiago-Frangos et al Nat Struct Mol Biol. 2023 Nov;30(11):167

    Insert

    Consensus I-E Leader and Consensus I-E Locus DNA
    

    Expression

    Bacterial

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge