We narrowed to 7,673 results for: Ski

1. pDONR223_GPR137B_p.Y135N

   Plasmid

   #82752

   Purpose

   Gateway Donor vector containing GPR137B, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   GPR137B (GPR137B Human)
   

   Use

   Gateway entry vector

   Mutation

   Y135N

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pDONR223_CCND1_p.E172K

   Plasmid

   #82733

   Purpose

   Gateway Donor vector containing CCND1, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   CCND1 (CCND1 Human)
   

   Use

   Gateway entry vector

   Mutation

   E172K

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDONR223_SERPINB5_p.I159S

   Plasmid

   #82734

   Purpose

   Gateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   SERPINB5 (SERPINB5 Human)
   

   Use

   Gateway entry vector

   Mutation

   I159S; S176P; p.190_192delTDTins25amino acids; p.…

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pDONR223_SERPINB5_p.D141A

   Plasmid

   #82735

   Purpose

   Gateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   SERPINB5 (SERPINB5 Human)
   

   Use

   Gateway entry vector

   Mutation

   p. D141A; p. 176S>P; p.190_192delTDTins25amino…

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDONR223_SERPINB5_p.A7T

   Plasmid

   #82736

   Purpose

   Gateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   SERPINB5 (SERPINB5 Human)
   

   Use

   Gateway entry vector

   Mutation

   p. A7T; p.176S>P; p. 190_192delTDTins25; p.194…

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pDONR223_SERPINB5_p.A42F

   Plasmid

   #82738

   Purpose

   Gateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   SERPINB5 (SERPINB5 Human)
   

   Use

   Gateway entry vector

   Mutation

   p.A42F; p.176S>P; p.190_192delTDTins25; p.194_…

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pDONR223_SERPINB5_p.A165T

   Plasmid

   #82741

   Purpose

   Gateway Donor vector containing SERPINB5, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   SERPINB5 (SERPINB5 Human)
   

   Use

   Gateway entry vector

   Mutation

   p. A165T; p.176S>P; p.190_192delTDTins25; p.19…

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pDONR223_HAVCR2_p.P6S

   Plasmid

   #82742

   Purpose

   Gateway Donor vector containing HAVCR2, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   HAVCR2 (HAVCR2 Human)
   

   Use

   Gateway entry vector

   Mutation

   p.P6S; p.R140L

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pET-Duet-ECHA(37-763) K351R-FLAG (no His-tag)

   Plasmid

   #96888

   Purpose

   expresses-flag tagged mouse ECHA(37-768) K351R in E.coli cells (no His-tag)

   Depositor

   Hening Lin

   Article

   Sadhukhan et al Proc Natl Acad Sci U S A. 2016 Apr 19;11

   Insert

   Trifunctional enzyme subunit alpha, mitochondrial (Hadha Mouse)
   

   Tags

   FLAG-tagged

   Expression

   Bacterial

   Mutation

   deleted amino acid 1-36, mutated lysine 351 to ar…

   Promoter

   T7

   Availability

   Academic Institutions and Nonprofits only

   

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10. pU6-pegRNA-LRRK2-G2019S-3b

    Plasmid

    #180433

    Purpose

    Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

    Depositor

    Frank Soldner

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    ncRNA targeting LRRK2-G2019S (LRRK2 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    LRRK2-G2019S

    Promoter

    U6

    Availability

    Academic Institutions and Nonprofits only

    

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11. pU6-pegRNA-LRRK2-G2019S-3c

    Plasmid

    #180434

    Purpose

    Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

    Depositor

    Frank Soldner

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    ncRNA targeting LRRK2-G2019S (LRRK2 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    LRRK2-G2019S

    Promoter

    U6

    Availability

    Academic Institutions and Nonprofits only

    

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12. pU6-pegRNA-LRRK2-G2019S-3d

    Plasmid

    #180435

    Purpose

    Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

    Depositor

    Frank Soldner

    Article

    Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

    Insert

    ncRNA targeting LRRK2-G2019S (LRRK2 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    LRRK2-G2019S

    Promoter

    U6

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCMV-T7-ABE8e-nSpRY-P2A-EGFP (KAC1069)

    Plasmid

    #185912

    Purpose

    pCMV and pT7 plasmid encoding human codon optimized ABE8e A-to-G base editor with nicakse SpRY(D10A/A61R/L1111R/D1135L/S1136W/G1218K/E1219Q/N1317R/A1322R/R1333P/R1335Q/T1337R) and P2A-EGFP

    Depositor

    Benjamin Kleinstiver

    Article

    Alves et al Nat Biomed Eng. 2023 Dec 6. doi: 10.1038

    Insert

    human codon optimized ABE8e-nSpRY-P2A-EGFP
    

    Use

    In vitro transcription; t7 promoter

    Tags

    BPNLS and BPNLS-3xFLAG-P2A-EGFP

    Expression

    Mammalian

    Mutation

    nSpRY=D10A/A61R/L1111R/D1135L/S1136W/G1218K/E1219…

    Promoter

    CMV and T7

    Available Since

    July 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pUCmini-iCAP-AAV9-X1.1

    Plasmid

    #196836

    Purpose

    non-standard AAV2 rep-AAV9-X1.1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system

    Depositor

    Viviana Gradinaru

    Article

    Chen et al Nat Commun. 2023 Jun 8;14(1):3345. doi:

    Insert

    Synthetic construct isolate AAV9-X1.1 VP1 gene
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    p41

    Available Since

    June 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLKO-Tet-On-YAP1-shRNA1

    Plasmid

    #176846

    Purpose

    lentiviral vector for doxycycline-inducible human YAP1 knockdown

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

    Insert

    YAP1-Sh1 (YAP1 Human)
    

    Use

    Lentiviral

    Available Since

    Nov. 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pDONR223_CFLAR_WT_V5

    Plasmid

    #82936

    Purpose

    Gateway Donor vector containing CFLAR, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, Matthew Meyerson, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    CFLAR (CFLAR Human)
    

    Use

    Gateway entry vector

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLV-TRE3G-YAP1-5SA-CMV-mCherry-T2A-Puro

    Plasmid

    #176851

    Purpose

    lentiviral vector for doxycycline-inducible YAP1 5SA constitutively active expression

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

    Insert

    hYAP1-5SA (YAP1 Human)
    

    Use

    Lentiviral

    Mutation

    S61A, S109A, S127A, S164A, S381A (phosphorylation…

    Available Since

    Nov. 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLV-TRE3G-hYAP1-CMV-mCherry-T2A-Puro

    Plasmid

    #176850

    Purpose

    lentiviral vector for doxycycline-inducible YAP1 overexpression

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

    Insert

    hYAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Mutation

    full length YAP1

    Available Since

    Nov. 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. RED

    Plasmid

    #139835

    Purpose

    Expresses RNase H1-EGFP- dCas9 fusion protein in human cells

    Depositor

    Karim Mekhail

    Article

    Abraham et al Nature. 2020 Sep;585(7824):298-302. doi:

    Insert

    RNase H1-EGFP-dCas9 (RNASEH1 RNase H1 (H. sapiens), dCas9 (S. pyogenes))
    

    Expression

    Mammalian

    Mutation

    dCas9 protein contains two mutations: D10A and H8…

    Promoter

    tet-inducible CMV

    Available Since

    Sept. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. dRED

    Plasmid

    #139836

    Purpose

    Expresses dRNase H1-EGFP-dCas9 fusion protein in human cells

    Depositor

    Karim Mekhail

    Article

    Abraham et al Nature. 2020 Sep;585(7824):298-302. doi:

    Insert

    dRNase H1-EGFP-dCas9 (RNASEH1 dRNase H1 (H. sapiens), dCas9 (S. pyogenes))
    

    Expression

    Mammalian

    Mutation

    RNase H1 protein contains D210N mutation. dCas9 …

    Promoter

    tet-inducible CMV

    Available Since

    Sept. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge