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CKMT1A gRNA (BRDN0001145999)

Plasmid

#75878

Purpose

3rd generation lentiviral gRNA plasmid targeting human CKMT1A

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CKMT1A,CKMT1B (CKMT1A Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PBK gRNA (BRDN0001145489)

Plasmid

#75573

Purpose

3rd generation lentiviral gRNA plasmid targeting human PBK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PBK (PBK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PAK3 gRNA (BRDN0001148041)

Plasmid

#75678

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PAK3 gRNA (BRDN0001148181)

Plasmid

#75679

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PAK3 gRNA (BRDN0001148485)

Plasmid

#75680

Purpose

3rd generation lentiviral gRNA plasmid targeting human PAK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PAK3 (PAK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PRKD1 gRNA (BRDN0001162219)

Plasmid

#77231

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKD1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKD1 (PRKD1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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RIPK2 gRNA (BRDN0001146369)

Plasmid

#76912

Purpose

3rd generation lentiviral gRNA plasmid targeting human RIPK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

RIPK2 (RIPK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SH3BP4 gRNA (BRDN0001149529)

Plasmid

#78087

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SH3BP4 gRNA (BRDN0001487091)

Plasmid

#78089

Purpose

3rd generation lentiviral gRNA plasmid targeting human SH3BP4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SH3BP4 (SH3BP4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEK gRNA (BRDN0001146784)

Plasmid

#75722

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEK (TEK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEK gRNA (BRDN0001148973)

Plasmid

#75724

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEK (TEK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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NRK gRNA (BRDN0001147558)

Plasmid

#76314

Purpose

3rd generation lentiviral gRNA plasmid targeting human NRK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NRK (NRK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TIE1 gRNA (BRDN0001147382)

Plasmid

#76686

Purpose

3rd generation lentiviral gRNA plasmid targeting human TIE1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TIE1 (TIE1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MDH1-miR-196b-PGK-GFP-Blast

Plasmid

#31513

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196b (Mir196b Mouse)

Use

Retroviral

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-324-PGK-GFP-Blas

Plasmid

#31517

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-324 (Mir324 Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-196a-2-PGK-GFP-Blast

Plasmid

#31511

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196a2 (Mir196a-2 Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
MDH1-miR-196bSM-PGK-GFP-Blast

Plasmid

#31514

Depositor

Chang-Zheng Chen

Article

Arnold et al Genome Res. 2011 May . 21(5):798-810.

Insert

miR-196b (Mir196b Mouse)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Available Since

Sept. 19, 2011

Availability

Academic Institutions and Nonprofits only
pLenti X1 Puro 8xGLI_minPro_Luc2p_Ren

Plasmid

#249282

Purpose

Dual-luciferase GLI reporter viral plasmid. 8xGLI binding site followed by minPro-luc2P expression, in addition to constitutive SV-40-driven Renilla luciferase expression.

Depositor

Ramiro Iglesias-Bartolome

Article

Krantz et al Cancer Res. 2025 Dec 29. doi: 10.1158/00

Insert

Luciferase

Use

Lentiviral

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pGL4.R_8xGLIBS_minPro_Luc2p_Ren

Plasmid

#249281

Purpose

Dual-luciferase GLI reporter plasmid. 8xGLI binding site followed by minPro-luc2P expression, in addition to constitutive SV-40-driven Renilla luciferase expression.

Depositor

Ramiro Iglesias-Bartolome

Article

Krantz et al Cancer Res. 2025 Dec 29. doi: 10.1158/00

Insert

Luciferase

Use

Luciferase

Expression

Mammalian

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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SIN-cPPT-G1B3-GFP-WPRE-miR124T

Plasmid

#245069

Purpose

Fluorescent reporter gene with miRNA-124 target sequence to repress transgene expression in neurons

Depositor

Nicole Déglon

Article

Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

Insert

EGFP, miR124T site

Use

Lentiviral

Expression

Mammalian

Promoter

Human G1B3 promoter

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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