We narrowed to 24,746 results for: CHI;

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SARS-CoV-2 Spike (S) Ectodomain Library B

Pooled Library

#157972

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available Since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library A

Pooled Library

#157971

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available Since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
4JDS

Plasmid

#60081

Purpose

Bacterial expression for structure determination; may not be full ORF

Depositor

Cheryl Arrowsmith

Insert

SETD7:DCC011-H01:C212434 (SETD7 Human)

Tags

6xHis

Expression

Bacterial

Mutation

See comments

Promoter

T7

Available Since

Oct. 22, 2014

Availability

Industry, Academic Institutions, and Nonprofits
AAV:ITR-EF1aCore-SaCas9-dual(U6-sgRNA(backbone))-ITR

Plasmid

#207878

Purpose

AAV vector encoding EF1a core promoter-driven SaCas9 and two sgRNA cloning sites w/ the engineered Sa Guide scaffold variant (BbsI and PaqCI for sgRNA cloning).

Depositor

Yeh-Hsing Lao

Article

Lao et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

Type

Empty backbone

Use

AAV and CRISPR

Expression

Mammalian

Available Since

Oct. 13, 2023

Availability

Academic Institutions and Nonprofits only

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AAV:ITR-EF1aCore-SaCas9-single(U6-sgRNA(backbone))-ITR

Plasmid

#207880

Purpose

AAV vector encoding EF1a core promoter-driven SaCas9 and single sgRNA cloning site w/ the engineered Sa Guide scaffold variant (BbsI for sgRNA cloning).

Depositor

Yeh-Hsing Lao

Article

Lao et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

Type

Empty backbone

Use

AAV and CRISPR

Expression

Mammalian

Available Since

Nov. 16, 2023

Availability

Academic Institutions and Nonprofits only

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plx304-PHB-V5

Plasmid

#122230

Purpose

Expresses human PHB attached to a V5 tag

Depositor

Alex Kentsis

Article

Ortiz et al JCI Insight. 2019 Aug 8;4(15). pii: 1270

Insert

Prohibitin (PHB1 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Available Since

Aug. 8, 2019

Availability

Academic Institutions and Nonprofits only

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pLKO-PHB-8

Plasmid

#122233

Purpose

Expresses shRNA targeting the coding sequence of human PHB

Depositor

Alex Kentsis

Article

Ortiz et al JCI Insight. 2019 Aug 8;4(15). pii: 1270

Insert

shRNA targeting PHB (see partial depositor seq) (PHB1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Aug. 8, 2019

Availability

Academic Institutions and Nonprofits only

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pLKO-PHB-6

Plasmid

#122232

Purpose

Expresses shRNA targeting the coding sequence of human PHB

Depositor

Alex Kentsis

Article

Ortiz et al JCI Insight. 2019 Aug 8;4(15). pii: 1270

Insert

shRNA targeting PHB (see partial depositor seq) (PHB1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Aug. 8, 2019

Availability

Academic Institutions and Nonprofits only

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pMXS-IRES-Blast HA-GPAT4-ΔNs5

Plasmid

#173169

Purpose

Retroviral vector to express sgRNA resistant HA tagged human GPAT4 with mutation in CHP1 binding site

Depositor

Kivanc Birsoy

Article

Zhu et al Mol Cell. 2019 Apr 4;74(1):45-58.e7. doi

Insert

Glycerol-3-Phosphate Acyltransferase 4 (GPAT4 Human)

Use

Retroviral

Tags

HA

Mutation

Synonymous mutations at sgRNA sites, amino acids …

Promoter

MMLV

Available Since

Aug. 27, 2021

Availability

Academic Institutions and Nonprofits only

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pMXS-IRES-Blast 3XFLAG-CHP1-myr_mut

Plasmid

#173167

Purpose

Retroviral vector to express sgRNA resistant 3XFLAG tagged human CHP1 with myristoylation site mutation

Depositor

Kivanc Birsoy

Article

Zhu et al Mol Cell. 2019 Apr 4;74(1):45-58.e7. doi

Insert

Calcineurin Like EF-Hand Protein 1 (CHP1 Human)

Use

Retroviral

Tags

3XFLAG

Mutation

Synonymous mutations at sgRNA sites, G2A, S6A

Promoter

MMLV

Available Since

Aug. 27, 2021

Availability

Academic Institutions and Nonprofits only

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Venus-BimEL(Bad)-pEGFP-C1

Plasmid

#166758

Purpose

To examine effect of swapping the BH3 region in full length BimEL with that of Bad

Depositor

David Andrews

Article

Liu et al Elife. 2019 Mar 12;8. pii: 37689. doi: 1

Insert

BimEL(Mus musculus)-(Bad BH3) (Bcl2l11, BAD Mouse, Human)

Tags

Venus

Expression

Mammalian

Mutation

BH3 region removed and inserted BH3 of human Bad …

Promoter

CMV

Available Since

March 29, 2021

Availability

Academic Institutions and Nonprofits only

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Human CRISPR Poison Exon Knockout Library

Pooled Library

#138084

Purpose

Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.

Depositor

Robert Bradley

Article

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

March 6, 2020

Availability

Academic Institutions and Nonprofits only
TJP3

Plasmid

#25310

Purpose

Bacterial expression for structure determination; may not be full ORF

Depositor

Cheryl Arrowsmith

Insert

TJP3:G508-L808:cH6 (TJP3 Human)

Tags

His

Expression

Bacterial

Mutation

Contains amino acids G508-L808

Available Since

April 4, 2016

Availability

Industry, Academic Institutions, and Nonprofits
pLKO-PHB-4

Plasmid

#122231

Purpose

Expresses shRNA targeting the 3' UTR of human PHB

Depositor

Alex Kentsis

Article

Ortiz et al JCI Insight. 2019 Aug 8;4(15). pii: 1270

Insert

PHB (PHB1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Aug. 8, 2019

Availability

Academic Institutions and Nonprofits only

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KIF13B

Plasmid

#25309

Purpose

Bacterial expression for structure determination; may not be full ORF

Depositor

Cheryl Arrowsmith

Insert

KIF13B:S4-K351:cH6 (KIF13B Human)

Tags

His

Expression

Bacterial

Mutation

Contains amino acids S4-K351

Available Since

Aug. 16, 2010

Availability

Industry, Academic Institutions, and Nonprofits
4MI0

Plasmid

#60097

Purpose

Baculovirus expression for structure determination; may not be full ORF

Depositor

Cheryl Arrowsmith

Insert

EZH2:JMC033-A03:C216172 (EZH2 Human)

Use

Baculovirus expression

Tags

6xHis

Mutation

See comments

Promoter

T7

Available Since

Oct. 22, 2014

Availability

Industry, Academic Institutions, and Nonprofits
pLXI_TRC403 LacZ

Plasmid

#111184

Purpose

Control inducible vector with LacZ (V5 tagged)

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

lacZ

Use

Lentiviral

Tags

V5

Promoter

TRE

Available Since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

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pLXI_TRC401 LacZ

Plasmid

#111183

Purpose

Control inducible vector with LacZ (V5 tagged)

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

lacZ

Use

Lentiviral

Tags

V5

Promoter

TRE

Available Since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003 Luciferase

Plasmid

#117072

Purpose

single guide RNA targeting Luciferase

Depositor

William Hahn

Article

Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

Insert

Luciferase

Use

CRISPR

Promoter

hU6

Available Since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

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pCri System

Plasmid Kit

#1000000058

Purpose

pCri System: plasmids for cytoplasmic and periplasmic/extracellular heterologous protein expression in Escherichia coli, Bacillus subtilis, and Pichia pastoris.

Depositor

F Xavier Gomis-Ruth

Available Since

April 15, 2015

Availability

Academic Institutions and Nonprofits only