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pX458-ARHGEF7/B-Pix

Plasmid

#241368

Purpose

Mammalian expression of SpCas9 and gRNA targeting ARHGEF7 (β-Pix)

Depositor

Gaudenz Danuser

Article

Weiss et al Sci Signal. 2025 May 20;18(887):eadk0922

Insert

ARHGEF7 gRNA (ARHGEF7 Human)

Expression

Mammalian

Promoter

U6

Available Since

Aug. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-IRES-NEO-NF2(1-27)-SNAP-tag

Plasmid

#241401

Purpose

Lentiviral expression of SNAP-tagged NF2 fragment (aa 1-27)

Depositor

Gaudenz Danuser

Article

Weiss et al Sci Signal. 2025 May 20;18(887):eadk0922

Insert

NF2 fragment (NF2 Human)

Use

Lentiviral

Tags

SNAP-tag

Mutation

aa 1-27

Promoter

CMV

Available Since

Aug. 27, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-UCE intron 3' deletion

Plasmid

#242182

Purpose

Express doxycycline inducible UCE intron 3' deletion of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron with 3' deletion (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 22, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-Unspliced CRNDE

Plasmid

#242177

Purpose

Express doxycycline inducible Unspliced CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

Unspliced CRNDE (CRNDE Human)

Expression

Mammalian

Mutation

PAM mutation (CCT to GTT)

Promoter

TRE3GS

Available Since

Aug. 22, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-UCE intron

Plasmid

#242180

Purpose

Express doxycycline inducible UCE-containing intron of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-UCE mutant

Plasmid

#242185

Purpose

Express doxycycline inducible UCE 32S binding mutation of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE mutant (CRNDE Human)

Expression

Mammalian

Mutation

ATTTTCATGGGC to TAAAAGTACCCG

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-UCE

Plasmid

#242184

Purpose

Express doxycycline inducible UCE intron of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

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XLone-UCE intron 5' deletion

Plasmid

#242181

Purpose

Express doxycycline inducible UCE intron 5' deletion of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron with 5' deletion (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

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pTRIP-SFFV-tagBFP-2A-FLAG-coK8

Plasmid

#235542

Purpose

To express tagBFP-2A-FLAG-coK8 (co = codon-optimized)

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

K8

Use

Lentiviral

Tags

FLAG

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRv2_IFNB1_gRNA_1

Plasmid

#235532

Purpose

gRNA against human IFNB1

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

IFNB1 (IFNB1 Human)

Use

Lentiviral

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

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