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pKlab264-pcDNA3-BRCA1(1314-end)-M1783T-V5-3xFLAG

Plasmid

#249017

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the M1783T mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

M1783T

Promoter

CMV Promoter

Available Since

Jan. 22, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab211-pcDNA3-BRCA1(1314-end)-L1705R-V5-3xFLAG

Plasmid

#249015

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the L1705R mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

L1705R

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab240-pcDNA3-BRCA1(1314-end)-Y1845D-V5-3xFLAG

Plasmid

#249016

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the Y1845D mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845D

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab981-pcDNA3-BRCA1(1314-end)-V1736A-V5-3xFLAG

Plasmid

#249018

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the V1736A mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

V1736A

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab224-pcDNA3-BRCA1(1314-end)-R1699W-V5-3xFLAG

Plasmid

#249019

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the R1699W mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

R1699W

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab223-pcDNA3-BRCA1(1314-end)-R1699Q-V5-3xFLAG

Plasmid

#249020

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the R1699Q mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

R1699Q

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab228-pcDNA3-BRCA1(1314-end)-S1715R-V5-3xFLAG

Plasmid

#249021

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the S1715R mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

S1715R

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab189-pcDNA3-BRCA1(1314-end)-A1708E-V5-3xFLAG

Plasmid

#249022

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the A1708E mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708E

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab521-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-Y1845F-STOP

Plasmid

#249009

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the Y1845F mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845F

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab522-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-Y1845D-STOP

Plasmid

#249010

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the Y1845D mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

Y1845D

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab524-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-G1788V-STOP

Plasmid

#249011

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the G1788V mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

G1788V

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab518-pcDNA3-3xFLAG-V5-BRCA1(1314-end)-A1708E-STOP

Plasmid

#249012

Purpose

This plasmid expresses the N-terminally 3x-FLAG tagged BRCT domain that contains the A1708E mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708E

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pKlab979-pcDNA3-BRCA1(1314-end)-A1708V-V5-3xFLAG

Plasmid

#249014

Purpose

This plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the A1708V mutation

Depositor

Georgios Karras

Article

Gracia et al Cell Rep. 2024 Feb 27;43(2):113803. doi:

Insert

BRCA1(1314aa-end) (BRCA1 Human)

Tags

3x-FLAG-V5

Expression

Mammalian

Mutation

A1708V

Promoter

CMV Promoter

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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STT3A Q260R

Plasmid

#246910

Purpose

Expresses an NGI-resistant version of STT3A, STT3A Q260R, in mammalian cells

Depositor

William Kaelin

Article

Lampson et al Cell. 2024 Apr 25;187(9):2209-2223.e16.

Insert

STT3A (STT3A Human)

Use

Lentiviral

Tags

HiBIT

Expression

Mammalian

Mutation

Q260R

Promoter

CMV

Available Since

Nov. 6, 2025

Availability

Academic Institutions and Nonprofits only

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STT3A E266K

Plasmid

#246908

Purpose

Expresses an NGI-resistant version of STT3A, STT3A E266K, in mammalian cells

Depositor

William Kaelin

Article

Lampson et al Cell. 2024 Apr 25;187(9):2209-2223.e16.

Insert

STT3A (STT3A Human)

Use

Lentiviral

Tags

HiBIT

Expression

Mammalian

Mutation

E266K

Promoter

CMV

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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STT3A F256P

Plasmid

#246909

Purpose

Expresses an NGI-resistant version of STT3A, STT3A F256P, in mammalian cells

Depositor

William Kaelin

Article

Lampson et al Cell. 2024 Apr 25;187(9):2209-2223.e16.

Insert

STT3A (STT3A Human)

Use

Lentiviral

Tags

HiBIT

Expression

Mammalian

Mutation

F256P

Promoter

CMV

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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UBC-TLR4-HA hygro

Plasmid

#246905

Purpose

Expresses HA-tagged human TLR4 in mammalian cells

Depositor

William Kaelin

Article

Lampson et al Cell. 2024 Apr 25;187(9):2209-2223.e16.

Insert

TLR4 (TLR4 Human)

Use

Lentiviral

Tags

HA

Expression

Mammalian

Promoter

UBC

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pDEST-ITGB1-V1

Plasmid

#215454

Purpose

Expression vector with integrin beta1 tagged with the BiFC V1 fragment

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Tags

Venus fragment 1 (V1)

Expression

Mammalian

Mutation

Silent mutations added to disrupt shRNA binding a…

Promoter

CMV

Available Since

Nov. 3, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pYO391

Plasmid

#235751

Purpose

Protein expression of ScVPS38, untagged + ScVPS34, untagged + FL ScVPS15-ZZ + ZZ-FL ScVPS30

Depositor

Roger Williams

Article

Rostislavleva et al Science. 2015 Oct 9;350(6257):aac7365. d

Inserts

VPS34 (VPS34 Budding Yeast)
VPS15 (VPS15 Budding Yeast)
VPS38 (VPS38 Budding Yeast)
VPS30 (VPS30 Budding Yeast)

Tags

3xTEV-ZZ and ZZ-3xTEV

Expression

Yeast

Mutation

S2A and T134A, I851R

Promoter

GALGAPDH

Available Since

Oct. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-Pax2

Plasmid

#241796

Purpose

Expresses Pax2 in mammalian cells.

Depositor

Diego Castrillon

Article

Sahoo et al J Clin Invest. 2025 Aug 15;135(16):e1909

Insert

PAX2 (PAX2 Human)

Expression

Mammalian

Available Since

Sept. 10, 2025

Availability

Academic Institutions and Nonprofits only

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