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Showing: 11171 - 11180 of 11261 results

  1. BAP1-C91A (siRNA resistant)

    Plasmid
    #108438
    Purpose
    Stable expression of BAP1-C91A (catalytically inactive mutant) in mammalian cells, gene has an introduced siRNA-resistance against siBAP1.
    Depositor
    Emanuela Felley-Bosco, Rolf Stahel
    Article
    Okonska et al Mol Cancer Ther. 2019 Oct 16. pii: 1535-
    Insert
    BAP1 (BAP1 Human)
    Expression
    Mammalian
    Mutation
    C91A: c.271T>G, c.272G>C; others: c.1641C&g…
    Promoter
    CMV
    Available Since
    Nov. 22, 2019
    Availability
    Academic Institutions and Nonprofits only
    108438-plasmid-map-sequence-id-209210

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  2. pCW-eGFP-FHA-SHLD2-m1

    Plasmid
    #114122
    Purpose
    Lentiviral vector for inducible expression of N-terminally tagged eGFP-RNF8 FHA domain-SHLD2, m1 mutant; 53BP1-independent recruitment to damaged chromatin
    Depositor
    Daniel Durocher
    Article
    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:
    Insert
    SHLD2 (m1 mutant) (SHLD2 Human)
    Use
    Lentiviral; Doxycycline inducible
    Tags
    RNF8 FHA domain (aa 2-160) and eGFP
    Expression
    Mammalian
    Mutation
    W489A, F494A, W495A mutations introduced
    Promoter
    TRE promoter, Tet ON
    Available Since
    Aug. 28, 2018
    Availability
    Industry, Academic Institutions, and Nonprofits
    114122-plasmid-map-sequence-id-220204

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  6. pUt-mPF-BACH1 Cas9-Resistant_AmpR

    Plasmid
    #199221
    Purpose
    LPUtopia-7 matching RMCE donor plasmid with Cas9-resistant GFP-BACH1 Positive-Feedback circuit (mPF-BACH1). Use BlastR for positive selection and HSV-TK for negative selection. 
    Depositor
    Gabor Balazsi
    Article
    Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d
    Insert
    rtTA-Advanced::P2A::EGFP::BACH1 (BACH1 Human)
    Tags
    EGFP
    Expression
    Mammalian
    Mutation
    silient mutation at nucleic acid 177 C changed to…
    Promoter
    tight TRE promoter
    Available Since
    June 28, 2023
    Availability
    Academic Institutions and Nonprofits only
    199221-plasmid-map-sequence-id-396541

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  7. pLenti-CD74-ROS1 L2000V

    Plasmid
    #183815
    Purpose
    Express CD74-ROS1 fusion (C6;R34) harboring ROS1 L2000V mutation in mammalian cells
    Depositor
    Aaron Hata
    Article
    Lin et al Clin Cancer Res. 2021 May 15;27(10):2899
    Inserts
    ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
    CD74 molecule (CD74 Human)
    Use
    Lentiviral
    Tags
    The fusion protein of CD74 exon 1-6 and ROS1 exon…
    Expression
    Mammalian
    Mutation
    L2000V
    Promoter
    CMV
    Available Since
    April 27, 2022
    Availability
    Academic Institutions and Nonprofits only
    183815-plasmid-map-sequence-id-360442

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  9. PiggyBac CAG eGFP-PolQ10A-FLAG P2A-BLAST

    Plasmid
    #249812
    Purpose
    Expresses the polymerase theta protein fused with N-terminal eGFP and C-terminal FLAG tag and mutated at serines 1289, 1482, 1486, 1488, 1493, 1555, 1563, 1628, 1635 and threonine 1755 into alanines
    Depositor
    Raphael Ceccaldi
    Article
    Gelot et al Nature. 2023 Sep;621(7978):415-422. doi:
    Insert
    Polymerase Theta (POLQ Human)
    Tags
    FLAG and eGFP
    Expression
    Mammalian
    Mutation
    serines 1289, 1482, 1486, 1488, 1493, 1555, 1563,…
    Promoter
    CAG
    Available Since
    March 6, 2026
    Availability
    Academic Institutions and Nonprofits only
    249812-plasmid-map-sequence-id-502074

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  10. pJC2747 - pET28-SKP1(A2P, ∆38-43, ∆71-82)-FBXO31(∆1-65, D334N)

    Plasmid
    #250278
    Purpose
    Recombinant production of SKP1(A2P, ∆38-43, ∆71-82) and 6His-Smt3-StrepII-FBXO31(∆1-65, D334N).
    Depositor
    Jacob Corn
    Article
    Muhar et al Nature. 2025 Feb;638(8050):519-527. doi:
    Inserts
    SKP1 (SKP1 Human)
    FBXO31 (FBXO31 Human)
    Tags
    6xHis-Smt3(SUMO)-StrepII
    Expression
    Bacterial
    Mutation
    A2P, ∆38-43, ∆71-82 and ∆1-65, D334N
    Promoter
    T7
    Available Since
    Jan. 28, 2026
    Availability
    Academic Institutions and Nonprofits only
    250278-plasmid-map-sequence-id-498555

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Showing: 11171 - 11180 of 11261 results