We narrowed to 3,043 results for: NAK

1. pXPR_BRD003-sgCh2-2

   Plasmid

   #125767

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-2
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pXPR_BRD003-sgCh2-4

   Plasmid

   #125768

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-4
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLX209-neo-active WRN

   Plasmid

   #125788

   Purpose

   constitutive, ectopic expression of human active WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   myc-active WRN (WRN Human)
   

   Tags

   5x myc

   Expression

   Mammalian

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. His6-TEV-CRBN-midi

   Plasmid

   #215330

   Purpose

   CRBN midi construct for use in crystallography and biophysical studies enabling ligand and degrader design

   Depositor

   Alessio Ciulli

   Article

   Kroupova et al Nat Commun. 2024 Oct 15;15(1):8885. doi:

   Insert

   CRBN (CRBN Human)
   

   Tags

   6xHis and TEV

   Expression

   Bacterial

   Mutation

   contains amino acids 41-187 followed by a Gly-Ser…

   Promoter

   lacI

   Available Since

   March 26, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pBABEpuro-ERBB2

   Plasmid

   #40978

   Depositor

   Matthew Meyerson

   Article

   Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

   Insert

   ERBB2 (ERBB2 Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Available Since

   Nov. 6, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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6. pBABEpuro-ERBB2 A775_G776insYVMA

   Plasmid

   #40982

   Depositor

   Matthew Meyerson

   Article

   Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

   Insert

   ERBB2 (ERBB2 Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   A775_G776insYVMA

   Available Since

   Nov. 6, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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7. pBABEpuro-ERBB2 A775_G776insV, G776C

   Plasmid

   #40979

   Depositor

   Matthew Meyerson

   Article

   Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

   Insert

   ERBB2 (ERBB2 Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   A775_G776insV, G776C

   Available Since

   Nov. 6, 2012

   Availability

   Academic Institutions and Nonprofits only

8. pHAGE2-TetOminiCMV-OSK

   Plasmid

   #136552

   Purpose

   Dox-inducible polycistronic reprogramming lentiviral vector expressing mouse Oct4, Sox2, Klf4

   Depositor

   Hans Schöler

   Article

   Velychko et al Cell Stem Cell. 2019 Oct 30. pii: S1934-

   Insert

   Oct4-P2A-Sox2-T2A-Klf4 (Klf4, Sox2, Pou5f1 Mouse)
   

   Use

   Lentiviral

   Expression

   Bacterial

   Promoter

   tetO-miniCMV (dox-inducible)

   Available Since

   March 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCR8 JARID2

   Plasmid

   #114443

   Purpose

   Entry vector for gateway cloning containing human JARID2 coding sequence

   Depositor

   Adrian Bracken

   Article

   Conway et al Mol Cell. 2018 May 3;70(3):408-421.e8. d

   Insert

   JARID2 (JARID2 Human)
   

   Use

   Gateway entry cloning

   Promoter

   None

   Available Since

   Sept. 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCDNA3.1-spikeRBD::∆ACE2 SURF

    Plasmid

    #206957

    Purpose

    Fluorescent reporter of the interaction between SARS-CoV-2 spike and human ACE2

    Depositor

    Xiaokun Shu

    Article

    Yang et al Nat Microbiol. 2023 Jan;8(1):121-134. do

    Inserts

    sars GU280_gp02, spike glycoprotein (S SARS-CoV-2)
    ACE2 (ACE2 Human)
    

    Tags

    cSURF, mCherry, and nSURF

    Expression

    Mammalian

    Mutation

    17-615 and RBD (319-541)

    Promoter

    CMV

    Available Since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDONR221-TAF15 Stop

    Plasmid

    #84895

    Purpose

    DONOR vector for Gateway cloning of TAF15

    Depositor

    Aaron Gitler

    Article

    Couthouis et al Proc Natl Acad Sci U S A. 2011 Dec 27;10

    Insert

    TAF15 (TAF15 Human)
    

    Use

    Gateway donor

    Promoter

    none

    Available Since

    Nov. 23, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLX209-neo-WRN K577M

    Plasmid

    #125790

    Purpose

    constitutive, ectopic expression of a helicase-dead mutant of human WRN (K577M)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-WRN K577M (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Mutation

    K577M (helicase-dead)

    Available Since

    June 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLX209-neo-WRN E84A

    Plasmid

    #125789

    Purpose

    constitutive, ectopic expression of an exonuclease-dead mutant of human WRN (E84A)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-WRN E84A (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Mutation

    E84A (exonuclease-dead)

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAd-M3cherry

    Plasmid

    #61041

    Purpose

    This plasmid mediates polycistronic expression of 4 genes: Ngn3, Pdx1, Mafa, and mCherry. It can be used to convert mouse pancreatic acinar cells to induced beta-like cells in vivo.

    Depositor

    Qiao Zhou

    Article

    Li et al Nat Biotechnol. 2014 Dec;32(12):1223-30.

    Inserts

    Ngn3 (Neurog3 Mouse)
    pdx1 (Pdx1 Mouse)
    Mafa (Mafa Mouse)
    monomeric cherry
    

    Use

    Adenoviral

    Available Since

    Dec. 11, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLD-puro-Cc-PRDX5WT-VA

    Plasmid

    #98688

    Purpose

    Lentiviral expression of human PRDX5-WT in mammalian cells

    Depositor

    Mohan Babu

    Article

    Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

    Insert

    PRDX5 (PRDX5 Human)
    

    Use

    Lentiviral

    Tags

    VA tag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLX209-neo-WRN E84A K577M

    Plasmid

    #125791

    Purpose

    constitutive, ectopic expression of an endonuclease/helicase-dead mutant of human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-WRN E84A/K577M (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Mutation

    E84A/K577M (exonuclease/helicase-dead)

    Available Since

    June 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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17. pDONR221-EWSR1 Stop

    Plasmid

    #84887

    Purpose

    DONOR vector for Gateway cloning of EWSR1

    Depositor

    Aaron Gitler

    Article

    Couthouis et al Hum Mol Genet. 2012 Jul 1;21(13):2899-91

    Insert

    EWSR1 (EWSR1 Human)
    

    Use

    Gateway donor

    Promoter

    none

    Available Since

    Nov. 23, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLEX_307-SOD1WT

    Plasmid

    #83444

    Purpose

    Mammalian expression of SOD1WT

    Depositor

    Mohan Babu

    Article

    Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

    Insert

    SOD1 (SOD1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF-1α

    Available Since

    Nov. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pHAGE2-TetOminiCMV-SKM

    Plasmid

    #136551

    Purpose

    Dox-inducible polycistronic reprogramming lentiviral vector expressing mouse Sox2, Klf4, cMyc

    Depositor

    Hans Schöler

    Article

    Velychko et al Cell Stem Cell. 2019 Oct 30. pii: S1934-

    Insert

    Sox2-T2A-Klf4-E2A-cMyc (Sox2, Klf4, Myc Mouse)
    

    Use

    Lentiviral

    Expression

    Bacterial

    Promoter

    tetO-miniCMV (dox-inducible)

    Available Since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pPHAGE_DLD-S456A-C-TAP

    Plasmid

    #83479

    Purpose

    Mammalian expression of the proteolysis-deficient mutant DLD-S456A.

    Depositor

    Mohan Babu

    Article

    Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

    Insert

    DLD (DLD Human)
    

    Use

    Lentiviral

    Tags

    TAP

    Expression

    Mammalian

    Mutation

    S456A

    Promoter

    CMV

    Available Since

    Nov. 10, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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