We narrowed to 4,223 results for: 424

1. pTWIN1-His6-Ssp-Httex1-43Q-A2C-A60C

   Plasmid

   #114623

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C & A60C cysteine mutations and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C, A60C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pTWIN1-His6-Ssp-Htt2-90(A2C)-49Q

   Plasmid

   #114627

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMSCV40-EF1a-hBCL10(1-185)-SO

   Plasmid

   #75258

   Purpose

   retroviral expression vector for expression of StrepOne-Tagged human BCL10 (AS 1-185)

   Depositor

   Ria Baumgrass

   Article

   Gabriel et al J Biol Chem. 2016 Sep 16. pii: jbc.M116.

   Insert

   Bcl10 (BCL10 Human)
   

   Use

   Retroviral

   Tags

   StrepOne Tag

   Expression

   Mammalian

   Mutation

   AS 1-185 (w/o C-terminus)

   Promoter

   pMSCV-LTRs, EF1a

   Available since

   June 8, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pTWIN1-His6-Ssp-Htt2-90-49Q-P90C

   Plasmid

   #114631

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pIS1 LPIN1

   Plasmid

   #60802

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains LPIN1 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   LPIN1 3'UTR and wild-type miR-155 binding site (LPIN1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   May 18, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. CDC7 gRNA (BRDN0001149415)

   Plasmid

   #76682

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDC7

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDC7 (CDC7 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. LentiCRISPR-B_sgRNA_EXOSC2 (pP18(T)_C3-AVA4067)

   Plasmid

   #239301

   Purpose

   Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC2

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   U6-driven sgRNA targeting EXOSC2 (EXOSC2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Aug. 4, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pET-28a KGA-WT

   Plasmid

   #227846

   Purpose

   To express in E. coli KGA-WT

   Depositor

   Sheng-cai Lin

   Article

   Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

   Insert

   KGA isoform (GLS Human)
   

   Use

   Tags

   HIS

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   June 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pET-28a GAC-WT

   Plasmid

   #227845

   Purpose

   To express in E. coli GAC-WT

   Depositor

   Sheng-cai Lin

   Article

   Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

   Insert

   GAC isoform (GLS Human)
   

   Use

   Tags

   HIS

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   June 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pAG8Ha-FLI1_DBD_R2L2

    Plasmid

    #188049

    Purpose

    Expresses His8-FLI1_DBD_R2L2(276-399_R337L_R340L_F362A) with a TEV site for removal of the His8 tag.

    Depositor

    David Libich

    Article

    Selig et al Proc Natl Acad Sci U S A. 2025 May 20;12

    Insert

    FLI1 (FLI1 Human)
    

    Use

    Tags

    His8

    Expression

    Bacterial

    Mutation

    deleted amino acids 1-275, 400-452, mutated R337L…

    Promoter

    T7

    Available since

    June 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAG8Ha-FLI1_DBD_deltaAlpha4

    Plasmid

    #188050

    Purpose

    Expresses His8-FLI1_DBD_deltaAlpha4(276-361) with a TEV site for removal of the His8 tag.

    Depositor

    David Libich

    Article

    Selig et al Proc Natl Acad Sci U S A. 2025 May 20;12

    Insert

    FLI1 (FLI1 Human)
    

    Use

    Tags

    His8

    Expression

    Bacterial

    Mutation

    deleted amino acids 1-275, 362-452

    Promoter

    T7

    Available since

    June 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pAG8Ha-FLI1_DBD(276-399_F362A)

    Plasmid

    #188047

    Purpose

    Expresses His8-FLI1_DBD(276-399_F362A) with a TEV site for removal of the His8 tag.

    Depositor

    David Libich

    Article

    Selig et al Proc Natl Acad Sci U S A. 2025 May 20;12

    Insert

    FLI1 (FLI1 Human)
    

    Use

    Tags

    His8

    Expression

    Bacterial

    Mutation

    deleted amino acids 1-275, 400-452, mutated F362A

    Promoter

    T7

    Available since

    June 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pAAV-hSyn-mCherry-Satb2 sesRNA-2a-msFlag-2a-tTA-WPRE

    Plasmid

    #239028

    Purpose

    Expression of mCherry, sesRNA in mammalian cells, with msFlag and tTA2 as efRNA.

    Depositor

    Josh Huang

    Article

    Qian et al Nature. 2022 Oct;610(7933):713-721. doi:

    Insert

    sesRNA for mouse Satb2 (Satb2 Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn

    Available since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. TFORF3379

    Plasmid

    #144855

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    ACTL6A (ACTL6A Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCAG-eCas9-T2A-EGFP-U6-gRNA targeting Nrl-no ITR and f1 ori

    Plasmid

    #234737

    Purpose

    All-in-one CRISPR/Cas9 vector encodes high-fidelity eSpCas9 and a gRNA targeting Nrl, efficiently reprogramming rod precursors into cone-like cells in the mouse retina.

    Depositor

    Kirill Martemyanov

    Article

    Zhao et al Nat Commun. 2025 Apr 22;16(1):3768. doi:

    Insert

    Nrl (Nrl Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAG

    Available since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. A1-LCD allW D262V

    Plasmid

    #234616

    Purpose

    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262V with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

    Depositor

    Tanja Mittag

    Article

    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

    Insert

    hnRNPA1_LCD_allW D262V (HNRNPA1 Human)
    

    Use

    Tags

    6xHis-TEV

    Expression

    Bacterial

    Mutation

    C-terminal domain (186-320) bearing familial ALS …

    Promoter

    T7

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. A1-LCD allW D262N

    Plasmid

    #234615

    Purpose

    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262N with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

    Depositor

    Tanja Mittag

    Article

    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

    Insert

    hnRNPA1_LCD_allW D262N (HNRNPA1 Human)
    

    Use

    Tags

    6xHis-TEV

    Expression

    Bacterial

    Mutation

    C-terminal domain (186-320) bearing familial ALS …

    Promoter

    T7

    Available since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pCMV-HA_N-human Bcl6

    Plasmid

    #137851

    Purpose

    Express Bcl6 in mammalian cells

    Depositor

    Bruce Beutler

    Article

    Misawa et al Sci Immunol. 2020 Jan 24;5(43):eaaz0085.

    Insert

    B cell lymphoma 6 (BCL6 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    April 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLentiCRISPR V2 Neo sgAGAP1_3

    Plasmid

    #233248

    Purpose

    Knock out of murine AGAP1

    Depositor

    David Bryant

    Article

    Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

    Insert

    AGAP1 (Agap1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLentiCRISPR V2 Neo sgAGAP1_2

    Plasmid

    #233247

    Purpose

    Knock out of murine AGAP1

    Depositor

    David Bryant

    Article

    Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

    Insert

    AGAP1 (Agap1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge