We narrowed to 3,367 results for: aaas

1. Gli2 truncation-pcw107-V5

   Plasmid

   #64626

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   GLI2 (truncation mutant) (GLI2 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Mutation

   truncated

   Promoter

   PGK

   Available Since

   May 12, 2015

   Availability

   Academic Institutions and Nonprofits only

2. shERK1a-mlpx-puro

   Plasmid

   #65228

   Purpose

   encodes a shRNA against ERK1

   Depositor

   Gerardo Ferbeyre

   Article

   Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

   Insert

   shRNA against ERK2 (MAPK1 Human)
   

   Expression

   Mammalian

   Available Since

   Aug. 12, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. pBScMXT + Slo1

   Plasmid

   #16194

   Depositor

   Larry Salkoff

   Article

   McCobb et al Am J Physiol. 1995 Sep . 269(3 Pt 2):H76

   Insert

   calcium-activated potassium channel (KCNMA1, Kcnma1 Mouse, Human)
   

   Use

   Xenopus oocyte expression

   Mutation

   N/A

   Available Since

   Jan. 10, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLKO.1-puro-shWRN2

   Plasmid

   #125782

   Purpose

   constitutive expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. CHUK gRNA (BRDN0001148194)

   Plasmid

   #77035

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CHUK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CHUK (CHUK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. FGFR1 gRNA (BRDN0001145494)

   Plasmid

   #76067

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human FGFR1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   FGFR1 (FGFR1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. AKT3 gRNA (BRDN0001144935)

   Plasmid

   #76218

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human AKT3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   AKT3 (AKT3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Aug. 16, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. AKT3 gRNA (BRDN0001145071)

   Plasmid

   #76219

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human AKT3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   AKT3 (AKT3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. AKT3 gRNA (BRDN0001147841)

   Plasmid

   #76220

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human AKT3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   AKT3 (AKT3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. JNK2 WT O/E (MAPK9)-pcw107-V5

    Plasmid

    #64617

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAPK9 (transcript variant JNK2-a2) (MAPK9 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Mutation

    none

    Promoter

    PGK

    Available Since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

11. CSF1R gRNA (BRDN0001147492)

    Plasmid

    #77037

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CSF1R

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CSF1R (CSF1R Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. FLAG-MKK6 (S207E,T211E)-pcw107

    Plasmid

    #64625

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K6 (MAP2K6 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Mutation

    S207E,T211E

    Promoter

    PGK

    Available Since

    June 10, 2015

    Availability

    Academic Institutions and Nonprofits only

13. myr-FLAG-MEK5-pcw107

    Plasmid

    #64620

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    MAP2K5 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    Flag and myristoylated

    Promoter

    PGK

    Available Since

    Nov. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

14. Lenti-sgArid2#2/Cre

    Plasmid

    #173576

    Purpose

    Expresses a Arid2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Arid2 (Arid2 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. ERBB3 gRNA (BRDN0001147088)

    Plasmid

    #77481

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ERBB3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ERBB3 (ERBB3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. FGFR2 gRNA (BRDN0001148071)

    Plasmid

    #76182

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGFR2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGFR2 (FGFR2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. FLAG-YAP2 (8SA)-pcw107

    Plasmid

    #64637

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    YAP2 (transcript variant 3) (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Mutation

    8SA*

    Promoter

    PGK

    Available Since

    Dec. 8, 2015

    Availability

    Academic Institutions and Nonprofits only

18. px330-Apob-4

    Plasmid

    #162551

    Purpose

    sgRNA targeting Apob

    Depositor

    Amaia Lujambio

    Article

    Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

    Insert

    sgRNA targeting Apob (Apob Mouse)
    

    Expression

    Mammalian

    Mutation

    None

    Promoter

    U6

    Available Since

    Feb. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. sgALK(Chr. Inv.)

    Plasmid

    #85569

    Purpose

    Expresses sgRNA targeting human ALK between exon 20 and 21

    Depositor

    Luca Grumolato

    Article

    Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

    Insert

    anaplastic lymphoma receptor tyrosine kinase (ALK Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

20. TTN gRNA (BRDN0001145502)

    Plasmid

    #76851

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TTN

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TTN (TTN Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge