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pAAV-hsyn-GRAB_HA1mut

Plasmid

#190475

Purpose

Express the histamine-insensitive control sensor GRAB_HA1mut in neurons

Depositor

Yulong Li

Publication

Dong et al Neuron. 2023 Mar 7:S0896-6273(23)00128-9

Insert

Histamine-insensitive sensor GRAB_HA1mut (control sensor)

Use

AAV

Promoter

hSyn

Available since

Dec. 8, 2022

Availability

Academic Institutions and Nonprofits only

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AAV-p3-PE(1152)-N-term

Plasmid

#187181

Purpose

p3-PE2-N-term(1152) in AAV2 backbone (ITRs)

Depositor

Gerald Schwank

Publication

Bock et al Sci Transl Med. 2022 Mar 16;14(636):eabl

Insert

PE2 from plasmid #132775

Use

AAV

Available since

Aug. 9, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV- CAG-h2BmRuby2FLAG

Plasmid

#116872

Purpose

Nuclear localized mRuby2FLAG

Depositor

Loren Looger

Publication

Economo et al Nature. 2018 Nov;563(7729):79-84. doi: 1

Insert

H2BmRuby2FLAG

Use

AAV

Available since

Nov. 21, 2018

Availability

Academic Institutions and Nonprofits only

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PP_070_pAAV_CAG_LR-Voltron2-P2A-LR-CheRiff-TS-eYFP-ER2

Plasmid

#203228

Purpose

Co-expressing membrane-localized Voltron2 and membrane-localized CheRiff.

Depositor

Adam Cohen

Publication

Park et al Nat Commun. 2025 Feb 4;16(1):1333. doi:

Insert

Membrane-localized optopatch for neuronal dendrites

Use

AAV

Expression

Mammalian

Promoter

CAG

Available since

July 5, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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pAAV-4mtD3cpv

Plasmid

#181874

Purpose

Expresses the FRET-based mitochondrial calcium indicator 4mtD3cpv under control of the CaMKIIa promoter

Depositor

Hilmar Bading

Publication

Hagenston et al J Biol Chem. 2021 Dec 20:101508. doi: 10

Insert

4mtD3cpv

Use

AAV and Adenoviral

Expression

Mammalian

Mutation

the 4mtD3cpv CDS differs from the recorded GeneBa…

Promoter

CaMKIIa

Available since

March 4, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-fDIO-mCherry-LATeNT

Plasmid

#240991

Purpose

Flp-dependent expression of LATeNT

Depositor

Alice Ting

Publication

Roh et al bioRxiv 2025.01.27.635161; doi: 10.1101/

Insert

mCherry-V5-LATeNT

Use

AAV

Tags

V5 (internal)

Expression

Mammalian

Available since

Dec. 10, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-HA-eLACCO2.1-NGR

Plasmid

#208096

Purpose

Biosensor for extracellular L-lactate

Depositor

Robert Campbell, Marie-Eve Paquet

Publication

Nasu et al Nat Commun. 2023 Oct 27;14(1):6598. doi:

Insert

eLACCO2.1

Use

AAV

Available since

Nov. 14, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-gfaABC1D-HA-eLACCO2.1-NGR

Plasmid

#208098

Purpose

Biosensor for extracellular L-lactate

Depositor

Robert Campbell, Marie-Eve Paquet

Publication

Nasu et al Nat Commun. 2023 Oct 27;14(1):6598. doi:

Insert

R-iLACCO1

Use

AAV

Available since

Nov. 14, 2023

Availability

Academic Institutions and Nonprofits only

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YA1629: pAAV_CAG-FLEX-paQuasAr3-s

Plasmid

#107703

Purpose

in vivo voltage imaging

Depositor

Adam Cohen

Publication

Adam et al Nature. 2019 May 1. pii: 10.1038/s41586-

Insert

paQuasAr3

Use

AAV

Expression

Mammalian

Available since

May 2, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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AiP20092 - pAAV-AiE2231m-minBG-iCre(R297T)-P2A-mScarlet-H2B-WPRE3-BGHpA

Plasmid

#241632

Purpose

AiE2231m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Bosiljka Tasic

Insert

iCre(R297T)-P2A-mScarlet-H2B

Use

AAV

Promoter

minBG

Available since

June 10, 2026

Availability

Academic Institutions and Nonprofits only

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AiP20078 - pAAV-AiE2255m-minBG-iCre(R297T)-P2A-mScarlet-H2B-WPRE3-BGHpA

Plasmid

#241622

Purpose

AiE2255m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Bosiljka Tasic

Insert

iCre(R297T)-P2A-mScarlet-H2B

Use

AAV

Promoter

minBG

Available since

March 10, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-CBh-aSyn-WPRE3-enSV40pA

Plasmid

#194244

Purpose

Expresses human alpha-Synuclein WT

Depositor

Michael J Fox Foundation MJFF

Insert

aSynuclein(WT) (SNCA Human)

Use

AAV

Promoter

CBh

Available since

Jan. 17, 2023

Availability

Industry, Academic Institutions, and Nonprofits

Cited by

1 Article

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pAAV-CAG-FLPo-3xmiR122-WPRE-HGHpA

Plasmid

#220938

Purpose

FLPo recombinase

Depositor

Chenghua Gu

Publication

Reference not available

Insert

Codon-optimized FLPe recombinase

Use

AAV

Available since

July 16, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-mRuby2-WPRE

Plasmid

#240051

Purpose

An AAV genome that ubiquitously expresses the fluorescent protein mRuby2 from the CAG promoter

Depositor

Mark Schnitzer

Publication

Haziza et al Cell, 188, 1-23, August 7, 2025. doi: 10

Insert

mRuby2

Use

AAV

Promoter

CAG

Available since

July 21, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV_CAG_Kinprola_PKA-mEGFP-NLS3__WPRE-SV40

Plasmid

#233365

Purpose

CAG driven expression of the PKA activity recorder Kinprola_PKA fused to mEGFP for mammalian cell expression through AAV transduction

Depositor

Kai Johnsson

Publication

Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

Insert

Kinprola_PKA-mEGFP-NLS3X

Use

AAV

Tags

mEGFP-NLS3X

Promoter

CAG

Available since

April 14, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV_CAG_NES-Kinprola_PKA-mTagBFP2_WPRE-SV40

Plasmid

#233364

Purpose

CAG driven expression of the PKA activity recorder Kinprola_PKA fused to mTagBFP2 for mammalian cell expression through AAV transduction

Depositor

Kai Johnsson

Publication

Sun et al Nat Chem Biol. 2025 Jul 10. doi: 10.1038

Insert

NES-Kinprola_PKA-mTagBFP2

Use

AAV

Tags

NES and mTagBFP2

Promoter

CAG

Available since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-GFAP-JEDI-1P-WPRE

Plasmid

#202616

Purpose

Genetically encoded voltage indicator (GEVI) JEDI-1P in AAV production vector for astrocytes specific expression using the promoter GFAP

Depositor

Francois St-Pierre

Publication

Lu et al Nat Commun. 2023 Oct 12;14(1):6423. doi:

Insert

JEDI-1P

Use

AAV

Expression

Mammalian

Promoter

GFAP

Available since

June 22, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-3xFLAG-WPRE

Plasmid

#127862

Purpose

pAAV plasmid expressing 3xFLAG under the hSyn promoter

Depositor

Florian Freudenberg

Publication

Candemir et al Eur Neuropsychopharmacol. 2016 Apr;26(4)

Insert

3xFLAG

Use

AAV

Promoter

hSyn

Available since

Aug. 2, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

3 Articles

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pAAV-IRES-hrGFP-mWnt5a

Plasmid

#89772

Purpose

Expresses mouse Wnt5a in mammalian cells

Depositor

Ken-Ichi Takemaru

Publication

Rodriguez et al J Neurosci. 2014 Jul 30;34(31):10285-97.

Insert

mouse Wnt5a (Wnt5a Mouse)

Use

AAV

Promoter

CMV

Available since

March 13, 2019

Availability

Academic Institutions and Nonprofits only

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pAAV-SYN-H-sDarken

Plasmid

#184797

Purpose

High affinity version of the Serotonin Sensor sDarken under the control of a hSyn Promoter.

Depositor

Olivia Masseck

Publication

Kubitschke et al Nat Commun. 2022 Dec 6;13(1):7525. doi:

Insert

H-sDarken

Use

AAV

Expression

Mammalian

Promoter

hSyn

Available since

Feb. 2, 2023

Availability

Academic Institutions and Nonprofits only

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