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pUDP010

Plasmid

#101166

Purpose

E. coli/S. cerevisiae amdS shuttle vector expressing a ribozyme flanked g-RNA for Cas9 editing targeting the gene SeILV6 in S. pastorianus (HH-gRNASeILV6-HDV)

Depositor

Jean-Marc Daran

Article

de Vries et al Microb Cell Fact. 2017 Dec 5;16(1):222.

Insert

HH-gRNA-HDV targetting SeILV6 in S. pastorianus

Use

CRISPR

Expression

Yeast

Promoter

ScTDH3

Available Since

Dec. 4, 2017

Availability

Academic Institutions and Nonprofits only

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ASF1B A4.2 gRNA

Plasmid

#90535

Purpose

3rd generation lentiviral gRNA plasmid targeting human ASF1B

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

ASF1B (Guide Designation A4.2)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 21, 2017

Availability

Academic Institutions and Nonprofits only

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ASF1B A3.2 gRNA

Plasmid

#90534

Purpose

3rd generation lentiviral gRNA plasmid targeting human ASF1B

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

ASF1B (Guide Designation A3.2)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 21, 2017

Availability

Academic Institutions and Nonprofits only

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TUBE1 F6.4 gRNA

Plasmid

#90929

Purpose

3rd generation lentiviral gRNA plasmid targeting human TUBE1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

TUBE1 (Guide Designation F6.4)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 19, 2017

Availability

Academic Institutions and Nonprofits only

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BUB3 A10.1 gRNA

Plasmid

#90557

Purpose

3rd generation lentiviral gRNA plasmid targeting human BUB3

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

BUB3 (Guide Designation A10.1)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

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NDEL1 F4.2 gRNA

Plasmid

#90792

Purpose

3rd generation lentiviral gRNA plasmid targeting human NDEL1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

NDEL1 (Guide Designation F4.2)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

Aug. 15, 2017

Availability

Academic Institutions and Nonprofits only

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NDEL1 F3.2 gRNA

Plasmid

#90790

Purpose

3rd generation lentiviral gRNA plasmid targeting human NDEL1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

NDEL1 (Guide Designation F3.2)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 24, 2017

Availability

Academic Institutions and Nonprofits only

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PPP2R5E C1.5 gRNA

Plasmid

#90855

Purpose

3rd generation lentiviral gRNA plasmid targeting human PPP2R5E

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

PPP2R5E (Guide Designation C1.5)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 25, 2017

Availability

Academic Institutions and Nonprofits only

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TPX2 H2.2 gRNA

Plasmid

#90919

Purpose

3rd generation lentiviral gRNA plasmid targeting human TPX2

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

TPX2 (Guide Designation H2.2)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 19, 2017

Availability

Academic Institutions and Nonprofits only

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CTPS1 E12.3 gRNA

Plasmid

#90645

Purpose

3rd generation lentiviral gRNA plasmid targeting human CTPS1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CTPS1 (Guide Designation E12.3)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 20, 2017

Availability

Academic Institutions and Nonprofits only

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CTPS1 E11.3 gRNA

Plasmid

#90644

Purpose

3rd generation lentiviral gRNA plasmid targeting human CTPS1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CTPS1 (Guide Designation E11.3)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 20, 2017

Availability

Academic Institutions and Nonprofits only

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FBXO5 D4.4 gRNA

Plasmid

#90687

Purpose

3rd generation lentiviral gRNA plasmid targeting human FBXO5

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

FBXO5 (Guide Designation D4.4)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 19, 2017

Availability

Academic Institutions and Nonprofits only

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MAD2L1BP F1.1 gRNA

Plasmid

#90744

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAD2L1BP

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

MAD2L1BP (Guide Designation F1.1)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 18, 2017

Availability

Academic Institutions and Nonprofits only

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MAD2L1BP F2.1 gRNA

Plasmid

#90745

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAD2L1BP

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

MAD2L1BP (Guide Designation F2.1)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

July 18, 2017

Availability

Academic Institutions and Nonprofits only

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pEP0003_pIVTRup(BsmBI)_ABEmax

Plasmid

#242537

Purpose

IVT

Depositor

Christoph Bock, Paul Datlinger

Article

Datlinger et al Nature. 2025 Oct;646(8086):963-972. doi:

Insert

ABEmax (NGG-ABE)

Use

CRISPR

Mutation

D10A

Available Since

Nov. 21, 2025

Availability

Academic Institutions and Nonprofits only

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pEP0004_pIVTRup(BsmBI)_AncBE4max

Plasmid

#242538

Purpose

IVT

Depositor

Christoph Bock, Paul Datlinger

Article

Datlinger et al Nature. 2025 Oct;646(8086):963-972. doi:

Insert

AncBE4max (NGG-CBE)

Use

CRISPR

Mutation

D10A

Available Since

Nov. 21, 2025

Availability

Academic Institutions and Nonprofits only

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LLP1017

Plasmid

#239939

Purpose

CaMV 35S driving the expression of dCas9-ZAT10(1x)

Depositor

Ryan Lister

Article

Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

Insert

CaMV 35S::dCas9-ZAT10(1x)

Use

CRISPR and Synthetic Biology

Mutation

N/A

Available Since

Oct. 27, 2025

Availability

Academic Institutions and Nonprofits only

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LLP1016

Plasmid

#239938

Purpose

CaMV 35S driving the expression of dCas9-ZAT10(2x)

Depositor

Ryan Lister

Article

Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

Insert

CaMV 35S::dCas9-ZAT10(2x)

Use

CRISPR and Synthetic Biology

Mutation

N/A

Available Since

Oct. 27, 2025

Availability

Academic Institutions and Nonprofits only

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LLP1023

Plasmid

#239945

Purpose

CaMV 35S driving the expression of dCas9

Depositor

Ryan Lister

Article

Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

Insert

CaMV 35S::dCas9

Use

CRISPR and Synthetic Biology

Mutation

N/A

Available Since

Oct. 27, 2025

Availability

Academic Institutions and Nonprofits only

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LLP1015

Plasmid

#239937

Purpose

CaMV 35S driving the expression of dCas9

Depositor

Ryan Lister

Article

Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

Insert

CaMV 35S::dCas9

Use

CRISPR and Synthetic Biology

Mutation

N/A

Available Since

Oct. 23, 2025

Availability

Academic Institutions and Nonprofits only

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