Addgene

We narrowed to 1,461 results for: p53

Showing: 1001 - 1050 of 1461 results

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CENPA B12.1 gRNA

Plasmid

#90611

Purpose

3rd generation lentiviral gRNA plasmid targeting human CENPA

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CENPA (Guide Designation B12.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
BUB1B A7.1 gRNA

Plasmid

#90554

Purpose

3rd generation lentiviral gRNA plasmid targeting human BUB1B

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

BUB1B (Guide Designation A7.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
BUB1B A8.1 gRNA

Plasmid

#90555

Purpose

3rd generation lentiviral gRNA plasmid targeting human BUB1B

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

BUB1B (Guide Designation A8.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
AURKB A4.1 gRNA

Plasmid

#90545

Purpose

3rd generation lentiviral gRNA plasmid targeting human AURKB

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

AURKB (Guide Designation A4.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
BUB1 A5.1 gRNA

Plasmid

#90552

Purpose

3rd generation lentiviral gRNA plasmid targeting human BUB1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

BUB1 (Guide Designation A5.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
BUB1 A6.1 gRNA

Plasmid

#90553

Purpose

3rd generation lentiviral gRNA plasmid targeting human BUB1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

BUB1 (Guide Designation A6.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 17, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
CCNB1 B4.1 gRNA

Plasmid

#90577

Purpose

3rd generation lentiviral gRNA plasmid targeting human CCNB1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CCNB1 (Guide Designation B4.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
CCNB1 B3.1 gRNA

Plasmid

#90576

Purpose

3rd generation lentiviral gRNA plasmid targeting human CCNB1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CCNB1 (Guide Designation B3.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
DBF4 C9.1 gRNA

Plasmid

#90646

Purpose

3rd generation lentiviral gRNA plasmid targeting human DBF4

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

DBF4 (Guide Designation C9.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
DSN1 C11.1 gRNA

Plasmid

#90656

Purpose

3rd generation lentiviral gRNA plasmid targeting human DSN1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

DSN1 (Guide Designation C11.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
DSN1 C12.1 gRNA

Plasmid

#90657

Purpose

3rd generation lentiviral gRNA plasmid targeting human DSN1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

DSN1 (Guide Designation C12.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
CENPF C6.1 gRNA

Plasmid

#90617

Purpose

3rd generation lentiviral gRNA plasmid targeting human CENPF

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

CENPF (Guide Designation C6.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
ESPL1 D7.1 gRNA

Plasmid

#90682

Purpose

3rd generation lentiviral gRNA plasmid targeting human ESPL1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

ESPL1 (Guide Designation D7.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
GINS1 D11.1 gRNA

Plasmid

#90694

Purpose

3rd generation lentiviral gRNA plasmid targeting human GINS1

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

GINS1 (Guide Designation D11.1)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 12, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
pGEX 4T-1/MKRN1

Plasmid

#78757

Purpose

To purify GST-tagged MKRN1 recombinant protein

Depositor

Jaewhan Song

Article

Lee et al EMBO J. 2009 Jul 22;28(14):2100-13. doi:

Insert

MKRN1 (MKRN1 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

Promoter

tac

Available since

June 15, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
ZNF668-Flag-D11

Plasmid

#45040

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion11 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 1-427

Promoter

Available since

June 13, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D9

Plasmid

#45038

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion9 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 1-267

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D8

Plasmid

#45037

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion8 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 1-190

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D7

Plasmid

#45036

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion7 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 1-83

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D6

Plasmid

#45035

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion6 (ZNF668 )

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 535-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D5

Plasmid

#45034

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion5 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 428-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D4

Plasmid

#45033

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion4 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 368-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D3

Plasmid

#45032

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion3 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 268-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D2

Plasmid

#45031

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion2 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 191-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
ZNF668-Flag-D1

Plasmid

#45030

Depositor

Shiaw-Yih Lin

Article

Hu et al Cancer Res. 2011 Oct 15;71(20):6524-34.

Insert

ZNF668 Deletion1 (ZNF668 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

contains aa 84-619

Promoter

Available since

June 6, 2013

Availability

Academic Institutions and Nonprofits only
human pirh2-(1-137)

Plasmid

#24879

Depositor

Cheryl Arrowsmith

Article

Sheng et al Nat Struct Mol Biol. 2008 Dec . 15(12):1

Insert

Pirh2 (RCHY1 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

Contains aa 1-137

Promoter

Available since

Aug. 5, 2010

Availability

Academic Institutions and Nonprofits only
human pirh2-(1-195)

Plasmid

#24880

Depositor

Cheryl Arrowsmith

Article

Sheng et al Nat Struct Mol Biol. 2008 Dec . 15(12):1

Insert

Pirh2 (RCHY1 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

Contains aa 1-195.

Promoter

Available since

Aug. 5, 2010

Availability

Academic Institutions and Nonprofits only
human pirh2-(138-261)

Plasmid

#24882

Depositor

Cheryl Arrowsmith

Article

Sheng et al Nat Struct Mol Biol. 2008 Dec . 15(12):1

Insert

Pirh2 (RCHY1 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

Contains aa 138-261.

Promoter

Available since

Aug. 5, 2010

Availability

Academic Institutions and Nonprofits only
human pirh2-(187-261)

Plasmid

#24883

Depositor

Cheryl Arrowsmith

Article

Sheng et al Nat Struct Mol Biol. 2008 Dec . 15(12):1

Insert

Pirh2 (RCHY1 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

Contains aa 187-261.

Promoter

Available since

Aug. 5, 2010

Availability

Academic Institutions and Nonprofits only
pLXSN_HPV16E7∆DLYC

Plasmid

#136588

Purpose

Retroviral vector for expression of RB-binding mutant of HPVE7

Depositor

Kevin Janes

Article

Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

Insert

HPV16E7∆DLYC

Use

Retroviral

Tags

Expression

Mutation

del aa 21-24, full length is 1-98

Promoter

Available since

Availability

Academic Institutions and Nonprofits only

Enlarge
Donor-PIGA

Plasmid

#153530

Purpose

Used as a donor vector for the targeted correction of a mutation in PIGA exon 6

Depositor

Hiroyuki Konishi

Article

Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7

Insert

PIGA (a 1,991-bp fragment from intron 5 and exon 6)

Use

Donor plasmid

Tags

N/A

Expression

Mutation

No mutation

Promoter

No promoter

Available since

Dec. 9, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pWZL hygro H-Ras V12

Plasmid

#18749

Depositor

Scott Lowe

Article

Serrano et al Cell. 1997 Mar 7. 88(5):593-602.

Insert

H-Ras V12 (HRAS Human)

Use

Retroviral

Tags

Expression

Mammalian

Mutation

V12

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only

Enlarge
MSCV Myc T58A puro

Plasmid

#18773

Depositor

Scott Lowe

Article

Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

Insert

myc T58A (MYC Human)

Use

Retroviral

Tags

3xHA

Expression

Mammalian

Mutation

T58A

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only

Enlarge
HA-Daxx/pRK5

Plasmid

#52023

Purpose

Expresses HA-Daxx in mammalian cells

Depositor

Xiaolu Yang

Article

Tang et al PLoS One. 2013;8(2):e55813. doi: 10.1371

Insert

HA-Daxx (DAXX Human)

Use

Tags

HA

Expression

Mammalian

Mutation

Promoter

CMV

Available since

April 7, 2014

Availability

Academic Institutions and Nonprofits only

Enlarge
Bnip3L pcDNA3.1

Plasmid

#17467

Depositor

Wafik El-Deiry

Article

Fei et al Cancer Cell. 2004 Dec . 6(6):597-609.

Insert

Bnip3L (BNIP3L Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 12, 2008

Availability

Academic Institutions and Nonprofits only

Enlarge
pOME0182

Plasmid

#178403

Purpose

Expresses KSHV K8.1 glycoprotein hyp tagged

Depositor

Dirk Dittmer

Article

Alzhanova et al PLoS Pathog. 2021 Jan 7;17(1):e1009033.

Insert

KSHV K8.1

Use

Tags

3xFLAG

Expression

Mammalian

Mutation

Promoter

Available since

Jan. 5, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pOME0116

Plasmid

#178392

Purpose

Expresses KSHV ORF 8 gB GQ994935 tagged

Depositor

Dirk Dittmer

Article

Alzhanova et al PLoS Pathog. 2021 Jan 7;17(1):e1009033.

Insert

KSHV ORF 8

Use

Tags

3xFLAG

Expression

Mammalian

Mutation

Promoter

Available since

Jan. 4, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pLPC-LaminA

Plasmid

#69059

Purpose

encodes the lamin A protein

Depositor

Gerardo Ferbeyre

Article

Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

Insert

LaminA (LMNA Human)

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 15, 2015

Availability

Academic Institutions and Nonprofits only
MSCV Myc IRES GFP

Plasmid

#18770

Depositor

Scott Lowe

Article

Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

Insert

Myc (Myc Mouse)

Use

Retroviral

Tags

IRES GFP

Expression

Mammalian

Mutation

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only
MSCV-mouse p19ARF-IRES-GFP

Plasmid

#107147

Purpose

Mammalian expression of mouse Arf

Depositor

Martine Roussel

Article

Kuo et al Cancer Res. 2003 Mar 1;63(5):1046-53.

Insert

Arf [alternative reading frame] (Cdkn2a Mouse)

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 3, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
IFI16-(192-393)-HinA (pcDNA3-FLAG)

Plasmid

#35062

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(192-393)-HinA (IFI16 Human)

Use

Tags

FLAG and His

Expression

Mammalian

Mutation

Contains HinA domain: aa 192-393

Promoter

CMV

Available since

April 4, 2012

Availability

Academic Institutions and Nonprofits only
pBV-luc TOP2A 1kb promoter

Plasmid

#138274

Purpose

Luciferase reporter plasmid driven by TOP2A promoter

Depositor

Wen Xue

Article

Kwan et al Hepatology. 2019 Jun 12. doi: 10.1002/he

Insert

TOP2A promoter sequence

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 18, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
IFI16-(515-710)-HinB (pcDNA3-FLAG)

Plasmid

#35063

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(515-710)-HinB (IFI16 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

Contains HinB domain: aa 515-710

Promoter

CMV

Available since

April 4, 2012

Availability

Academic Institutions and Nonprofits only
pCEP-WAF1-AS

Plasmid

#16448

Depositor

Bert Vogelstein

Article

el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

Insert

WAF1 antisense (CDKN1A Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 7, 2008

Availability

Academic Institutions and Nonprofits only
pOME0180

Plasmid

#178402

Purpose

Expresses KSHV ORF50 hyp tagged

Depositor

Dirk Dittmer

Article

Alzhanova et al PLoS Pathog. 2021 Jan 7;17(1):e1009033.

Insert

KSHV ORF 50

Use

Tags

3xFLAG

Expression

Mammalian

Mutation

Promoter

Available since

Jan. 5, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pFLAG-ING2

Plasmid

#13295

Depositor

Curtis Harris

Article

Pedeux et al Mol Cell Biol. 2005 Aug . 25(15):6639-48

Insert

ING2 (INGX Human)

Use

Tags

Flag

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 16, 2006

Availability

Academic Institutions and Nonprofits only
MSCV Myc P57S IRES GFP

Plasmid

#18771

Depositor

Scott Lowe

Article

Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

Insert

myc P57S (MYC Human)

Use

Retroviral

Tags

IRES GFP

Expression

Mammalian

Mutation

P57S

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only
pcDNA3-ING2

Plasmid

#13294

Depositor

Curtis Harris

Article

Pedeux et al Mol Cell Biol. 2005 Aug . 25(15):6639-48

Insert

ING2 (INGX Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 16, 2006

Availability

Academic Institutions and Nonprofits only
pLPC H-Ras V12

Plasmid

#18741

Depositor

Scott Lowe

Article

Serrano et al Cell. 1997 Mar 7. 88(5):593-602.

Insert

H-Ras V12 (HRAS Human)

Use

Retroviral

Tags

Expression

Mammalian

Mutation

V12

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only
MSCV N-term HA-FLAG puro BRD7

Plasmid

#41934

Depositor

Stephen Elledge

Article

Burrows et al Proc Natl Acad Sci U S A. 2010 Aug 10;10

Insert

BRD7 (BRD7 Human)

Use

Retroviral

Tags

HA-Flag

Expression

Mammalian

Mutation

Promoter

Available since

April 26, 2013

Availability

Academic Institutions and Nonprofits only

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