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pcDNA3.1(-).TagRFP.T-2A-V5-S404D.Tau2N4R-WPRE

Plasmid

#226391

Purpose

Expresses tau propagation ORF with V5 tag on S404D mutant 2N4R tau

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

TagRFP.T.2A.V5

Expression

Mammalian

Mutation

S404D, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(-).TagRFP.T-2A-V5-T217D.Tau2N4R-WPRE

Plasmid

#226392

Purpose

Expresses tau propagation ORF with V5 tag on T217D mutant 2N4R tau

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

TagRFP.T.2A.V5

Expression

Mammalian

Mutation

T217D, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(-).TagRFP.T-2A-V5-T403D.Tau2N4R-WPRE

Plasmid

#226393

Purpose

Expresses tau propagation ORF with V5 tag on T403D mutant 2N4R tau

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

TagRFP.T.2A.V5

Expression

Mammalian

Mutation

T403D, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(-).TagRFP.T-2A-V5-T181D.Tau2N4R-WPRE

Plasmid

#226394

Purpose

Expresses tau propagation ORF with V5 tag on T181D mutant 2N4R tau

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

TagRFP.T.2A.V5

Expression

Mammalian

Mutation

T181D, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(-).TagRFP.T-2A-V5-T231D.Tau2N4R-WPRE

Plasmid

#226395

Purpose

Expresses tau propagation ORF with V5 tag on T231D mutant 2N4R tau

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

TagRFP.T.2A.V5

Expression

Mammalian

Mutation

T231D, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pET28.His.3C.20D3Q.Tau2N4R

Plasmid

#226397

Purpose

Expresses his-tagged, 3C-cleavable 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

His.3C

Expression

Bacterial

Mutation

20D3Q, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pET28.His.3C.8D2Q.Tau2N4R

Plasmid

#226398

Purpose

Expresses his-tagged, 3C-cleavable 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT synthetic, Human)

Tags

His.3C

Expression

Bacterial

Mutation

8D2Q.Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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Anti-Neuroligin-3 [N496/21R]

Plasmid

#225401

Purpose

Mammalian Expression Plasmid of anti-Neuroligin-3 (Rat) IgG2a R-mAb. Derived from hybridoma N496/21.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Anti-Neuroligin-3 (Rattus norvegicus) recombinant (Mouse) monoclonal antibody. (Nlgn3 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Oct. 15, 2024

Availability

Academic Institutions and Nonprofits only

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SFFV-SOX17-Brd 435

Plasmid

#219348

Purpose

Transcription factor SOX17 with a specific barcode assigned.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

SOX17 (SOX17 Human)

Use

Lentiviral

Promoter

The spleen focus-forming virus (SFFV) promoter

Available Since

Oct. 15, 2024

Availability

Academic Institutions and Nonprofits only

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SFFV-ATF6B-Brd 142

Plasmid

#219106

Purpose

Transcription factor ATF6B with a specific barcode assigned.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

ATF6B (ATF6B Human)

Use

Lentiviral

Promoter

The spleen focus-forming virus (SFFV) promoter

Available Since

Oct. 15, 2024

Availability

Academic Institutions and Nonprofits only

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Anti-Neuroligin-3 [N496/79R]

Plasmid

#225402

Purpose

Mammalian Expression Plasmid of anti-Neuroligin-3 (Rat) IgG2a R-mAb. Derived from hybridoma N496/79.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Anti-Neuroligin-3 (Rattus norvegicus) recombinant (Mouse) monoclonal antibody. (Nlgn3 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Oct. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pMX-Sox17-p2A-Erg-t2A-GFP

Plasmid

#222496

Purpose

mouse fibroblast-to-endothelial cell direct reprogramming

Depositor

Li Qian

Article

Farber et al Nat Commun. 2024 May 16;15(1):4170. doi:

Inserts

Sox17 (Sox17 Mouse)
Erg (Erg )
EGFP

Use

Retroviral

Available Since

Aug. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-IDR4-mCh-Cry2WT-NLS

Plasmid

#221920

Purpose

Expression of CBP IDR4 fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP IDR4 (aa 662-787) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the IDR4 region (aa 662-787); insert…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-CFID-mCh-Cry2WT-NLS

Plasmid

#221923

Purpose

Expression of CBP CFID fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP CFID (aa 1892-2441) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the CBP-FUS interaction domain (CFID…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-IDR3-mCh-Cry2WT-NLS

Plasmid

#221919

Purpose

Expression of CBP IDR3 fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP IDR3 (aa 441-587) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the IDR3 region (aa 441 - 587); inse…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-AL-mCh-Cry2WT-NLS

Plasmid

#221924

Purpose

Expression of CBP autoregulatory loop (AL) fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP AL (aa 1529-1607) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the autoregulatory loop (AL) (aa 152…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-IDR7-mCh-Cry2WT-NLS

Plasmid

#221922

Purpose

Expression of CBP IDR7 fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP IDR7 (aa 2109-2434) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the IDR7 region (aa 2109 - 2434); in…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-IDR6-mCh-Cry2WT-NLS

Plasmid

#221921

Purpose

Expression of CBP IDR6 fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP IDR6 (aa 1856-2090) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the IDR6 region (aa 1856-2090); inse…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pHR-IDR1-mCh-Cry2WT-NLS

Plasmid

#221918

Purpose

Expression of CBP IDR1 fragment fused to optogenetic protein mCh-Cry2WT

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP IDR1 (aa 72-175) (CREBBP Human)

Use

Lentiviral

Tags

mCherry

Expression

Mammalian

Mutation

insertion of the IDR1 region (aa 72 - 175); inser…

Available Since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdCFIDKTG

Plasmid

#221917

Purpose

Transient expression of GFP-tagged CBPdeltaCFIDKTGL in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBP (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of the CBP-FUS interaction domain (CFID)…

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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