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pDONR-GNAQ Q209P sgRES OPEN

Plasmid

#241966

Purpose

Gateway entry vector containing GNAQ Q209P sgRES

Depositor

Rizwan Haq

Publication

Shettigar et al Proc Natl Acad Sci U S A. 2026 Jul 28;12

Insert

GNAQ Q209P sgRES (GNAQ Human)

Use

Gateway Cloning

Mutation

Q209P, sgRES

Available since

July 15, 2026

Availability

Academic Institutions and Nonprofits only

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pDONR-GNAQ Q209P sgRES CLOSED

Plasmid

#241949

Purpose

Expresses a GNAQ guide RNA resistant GNAQ Q209P mutant protein

Depositor

Rizwan Haq

Publication

Shettigar et al Proc Natl Acad Sci U S A. 2026 Jul 28;12

Insert

GNAQ Q209P sgRES (GNAQ Human)

Use

Gateway Cloning

Mutation

Q209P, sgRES

Available since

July 15, 2026

Availability

Academic Institutions and Nonprofits only

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LentiGuide Puro-P2A-mCherry-sgGNAQ #3

Plasmid

#241931

Purpose

Expresses mCherry and an sgRNA targetting human GNAQ

Depositor

Rizwan Haq

Publication

Shettigar et al Proc Natl Acad Sci U S A. 2026 Jul 28;12

Insert

sgGNAQ #3 (GNAQ Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Available since

July 15, 2026

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(K55R)-Avi

Plasmid

#245186

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

K55R

Available since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(T52S)-Avi

Plasmid

#245185

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

T52S

Available since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(L43F)-Avi

Plasmid

#245184

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

L43F

Available since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(T42A)-Avi

Plasmid

#245183

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

T42A

Available since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-C-SH2(R138Q)-Avi

Plasmid

#245189

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 C-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

R138Q

Available since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(E76K)-Avi

Plasmid

#245187

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

E76K

Available since

Oct. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-C-SH2(E139D)-Avi

Plasmid

#245190

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Publication

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 C-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

E139D

Available since

Sept. 29, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA1

Plasmid

#220120

Purpose

Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d start codon site by U6 promoter

Depositor

Yuxuan Guo

Publication

Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

Insert

MYL2, TadA, nSauriCas9

Use

AAV

Promoter

MYL2

Available since

Jan. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA6

Plasmid

#220122

Purpose

Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron6 5' splice site by U6 promoter

Depositor

Yuxuan Guo

Publication

Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

Insert

MYL2, TadA, nSauriCas9

Use

AAV

Promoter

MYL2

Available since

Jan. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA7

Plasmid

#220124

Purpose

Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter

Depositor

Yuxuan Guo

Publication

Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

Insert

MYL2, TadA, nSauriCas9

Use

AAV

Promoter

MYL2

Available since

Jan. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-MYL2-HA-TadA8e-Sauri-U6-Camk2d sgRNA7

Plasmid

#220127

Purpose

Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter, and add an HA tag fused to TadA

Depositor

Yuxuan Guo

Publication

Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

Insert

MYL2, TadA, nSauriCas9

Use

AAV

Tags

HA tag

Promoter

MYL2

Available since

Jan. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pSpCas9(BB)-2A-GFP_MAPRE1-KI-gRNA#3

Plasmid

#197426

Purpose

π-element knock-in into exon 5 of MAPRE1

Depositor

Torsten Wittmann

Publication

Dema et al Elife. 2023 Jan 30;12:e84143. doi: 10.75

Insert

MAPRE1 gRNA #3 (targets Exon 5) for π-element knock-in (MAPRE1 Human)

Expression

Mammalian

Available since

June 26, 2023

Availability

Academic Institutions and Nonprofits only

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pIW040

Plasmid

#134127

Purpose

Bacterial expression of human Ska1 microtubule binding domain (MTBD)

Depositor

Iain Cheeseman

Publication

Monda et al Curr Biol. 2017 Dec 4;27(23):3666-3675.e

Insert

His-Precission-human Ska1 MTBD (SKA1 Human)

Expression

Bacterial

Mutation

aa 132-255 R236A

Available since

Feb. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pIW039

Plasmid

#134126

Purpose

Bacterial expression of human Ska1 microtubule binding domain (MTBD)

Depositor

Iain Cheeseman

Publication

Monda et al Curr Biol. 2017 Dec 4;27(23):3666-3675.e

Insert

His-Precission-human Ska1 MTBD (SKA1 Human)

Expression

Bacterial

Mutation

aa 132-255 and K203A K206A

Available since

Feb. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pIW028

Plasmid

#134125

Purpose

Bacterial expression of human Ska1 microtubule binding domain (MTBD)

Depositor

Iain Cheeseman

Publication

Monda et al Curr Biol. 2017 Dec 4;27(23):3666-3675.e

Insert

His-Precission-human Ska1 MTBD (SKA1 Human)

Expression

Bacterial

Mutation

aa 132-255 and K183A K184A

Available since

Feb. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pIW088

Plasmid

#134135

Purpose

Retroviral expression of GFP-Ska1

Depositor

Iain Cheeseman

Publication

Monda et al Curr Biol. 2017 Dec 4;27(23):3666-3675.e

Insert

GFP-human Ska1 CRISPR/Cas9 hardened (SKA1 Human)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Mutation

CRISPR resistant, K223A K226A

Available since

Jan. 30, 2020

Availability

Academic Institutions and Nonprofits only

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pIW085

Plasmid

#134134

Purpose

Retroviral expression of GFP-Ska1

Depositor

Iain Cheeseman

Publication

Monda et al Curr Biol. 2017 Dec 4;27(23):3666-3675.e

Insert

GFP-human Ska1 CRISPR/Cas9 hardened (SKA1 Human)

Use

Retroviral

Tags

GFP

Expression

Mammalian

Mutation

CRISPR resistant, K183A K184A

Available since

Jan. 30, 2020

Availability

Academic Institutions and Nonprofits only

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