We narrowed to 16,039 results for: GRN

1. lentiGuide-chr20-49345720-gRNA3

   Plasmid

   #232625

   Purpose

   Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

   Depositor

   Claes Wadelius

   Article

   Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

   Insert

   S. pyogenes sgRNA cassette
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   April 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLentiCRISPR V2 Neo PTEN sgRNA5

   Plasmid

   #233246

   Purpose

   Knock out of murine PTEN

   Depositor

   David Bryant

   Article

   Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

   Insert

   PTEN (Pten Mouse)
   

   Use

   Lentiviral

   Available Since

   March 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLentiCRISPR V2 Neo PTEN sgRNA2

   Plasmid

   #233245

   Purpose

   Knock out of murine PTEN

   Depositor

   David Bryant

   Article

   Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

   Insert

   PTEN (Pten Mouse)
   

   Use

   Lentiviral

   Available Since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. esgRNA_NbATML1-2pro and NbATML1-1pro

   Plasmid

   #231155

   Purpose

   T-DNA encoding TRV2 with mobile gRNAs targeting NbATML1-2pro and NbATML1-1pro

   Depositor

   Daniel Voytas

   Article

   Liu et al Plant Physiol. 2024 Mar 29;194(4):2229-2

   Insert

   mobile gRNAs targeting NbATML1-2pro and NbATML1-1pro
   

   Expression

   Plant

   Promoter

   PEBV sub-genomic

   Available Since

   Jan. 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLentiCRISPR v2 puro mGSDME gRNA2

   Plasmid

   #223522

   Purpose

   Knocking out mGSDME in mouse cells

   Depositor

   Judy Lieberman

   Article

   Zhang et al Nature. 2020 Mar;579(7799):415-420. doi:

   Insert

   GSDME (GSDME Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Jan. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLentiCRISPR v2 puro mGSDME gRNA1

   Plasmid

   #223521

   Purpose

   Knocking out mGSDME in mouse cells

   Depositor

   Judy Lieberman

   Article

   Zhang et al Nature. 2020 Mar;579(7799):415-420. doi:

   Insert

   GSDME (GSDME Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Jan. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pM148: pAAV.CMV-Cas13e-NT sgRNA

   Plasmid

   #203446

   Purpose

   Plasmid expressing active RfxCas13d with non-targeting gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-non targeting (NT) sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCAG-3xGFP11-mem-3xPax7gRNA

   Plasmid

   #224571

   Purpose

   Ubiquitous expression plasmid with CAG promoter (CMV immediate early enhancer, chicken beta actin promoter), three unique Pax7 gRNAs with ribozyme self-cleavage, three membrane split GFP(11) reporter.

   Depositor

   Erica Hutchins

   Article

   Kim et al Dev Biol. 2024 Nov 30:S0012-1606(24)0026

   Insert

   3xGFP11
   

   Use

   CRISPR

   Tags

   Membrane Localization Signal

   Mutation

   Codon optimized

   Available Since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTBL3428 MTK234-LacO-BtoApegRNA

   Plasmid

   #226669

   Purpose

   MTK234 part containing lac-inducible variant of the hU6 promoter driving a B to A pegRNA

   Depositor

   Chang Liu

   Article

   Loveless et al bioRxiv 2021.11.05.467507

   Insert

   hU6-LacOS-BtoApegRNA
   

   Use

   CRISPR and Synthetic Biology

   Expression

   Mammalian

   Promoter

   hU6-LacOS

   Available Since

   Nov. 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pTBL3331 MTK234-TetO-AtoBpegRNA

    Plasmid

    #226668

    Purpose

    MTK234 part containing tet-inducible variant of the hU6 promoter driving an A to B pegRNA

    Depositor

    Chang Liu

    Article

    Loveless et al bioRxiv 2021.11.05.467507

    Insert

    hU6-TetO-AtoBpegRNA
    

    Use

    CRISPR and Synthetic Biology

    Expression

    Mammalian

    Promoter

    hU6-TetO

    Available Since

    Nov. 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pGL3-Ctr1-gRNA-EGFP

    Plasmid

    #226000

    Purpose

    Negative control for CRISPRi-KD

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    negtive control sgRNA of no specific targets in human genome
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGL3-Ctr2-gRNA-EGFP

    Plasmid

    #226001

    Purpose

    Negative control for CRISPRi-KD

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    negtive control sgRNA of no specific targets in human genome
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pGL3-hL1-gRNA1-EGFP

    Plasmid

    #226002

    Purpose

    CRISPRi-KD of human LINE1

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human L1HS
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pGL3-hL1-gRNA2-EGFP

    Plasmid

    #226003

    Purpose

    CRISPRi-KD of human LINE1

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human L1HS
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGL3-NCL-gRNA1-EGFP

    Plasmid

    #226004

    Purpose

    CRISPRi-KD of human Nucleolin

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human Nucleolin (NCL Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGL3-NCL-gRNA2-EGFP

    Plasmid

    #226005

    Purpose

    CRISPRi-KD of human Nucleolin

    Depositor

    Miguel Ramalho-Santos

    Article

    Zhang et al Dev Cell. 2024 Oct 14:S1534-5807(24)0057

    Insert

    sgRNA targeting human Nucleolin (NCL Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. BPK1520-FXR1-N202S-gRNA

    Plasmid

    #225481

    Purpose

    Express gRNA for FXR1

    Depositor

    Christine Mayr

    Article

    Chen et al Cell. 5 August 2024. doi: 10.1016/j.cell

    Insert

    gRNA for editing FXR1-N202S (FXR1 Human)
    

    Use

    CRISPR

    Promoter

    hU6

    Available Since

    Oct. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. 3'-com-gRNA GG backbone (MOBE1-4)

    Plasmid

    #219947

    Purpose

    Golden gate backbone for mammalian expression of Sp-gRNA with 3'-com

    Depositor

    Alexis Komor

    Article

    Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103

    Insert

    gRNA-com-3'end (S. pyogenes Cas9)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. 3'MS2-gRNA GG backbone (MOBE1-2)

    Plasmid

    #219948

    Purpose

    Golden gate backbone for mammalian expression of Sp-gRNA with 3'-MS2

    Depositor

    Alexis Komor

    Article

    Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103

    Insert

    gRNA-MS2-3'end (S. pyogenes Cas9)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. mPLD3-sgRNA-Cas9-mcherry

    Plasmid

    #199700

    Purpose

    encodes sgRNA for mouse PLD3 KO, (target 217-223aa) plus Cas9-P2A-mCherry

    Depositor

    David Nemazee

    Insert

    hSpCas9
    

    Use

    CRISPR

    Tags

    P2A-RFP

    Expression

    Mammalian

    Promoter

    U6 promoter

    Available Since

    May 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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