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lenti-sgRNA(MS2)_zeo_hCYP3A4_enhancer_guide1

Plasmid

#176839

Purpose

To recruit SAM complex to human CYP3A4 proximal enhancer.

Depositor

Rudolf Jaenisch

Article

Ma et al Cell Stem Cell. 2022 Apr 13. pii: S1934-

Insert

Human CYP3A4 proximal enhancer sgRNA for activation

Expression

Mammalian

Promoter

U6

Available Since

Nov. 1, 2021

Availability

Academic Institutions and Nonprofits only

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lenti-sgRNA(MS2)_zeo_hPDX1_promoter_guide1

Plasmid

#176838

Purpose

To induce human PDX1 expression by recruiting SAM complex to PDX1 promoter

Depositor

Rudolf Jaenisch

Article

Ma et al Cell Stem Cell. 2022 Apr 13. pii: S1934-

Insert

sgPDX1

Expression

Mammalian

Promoter

U6

Available Since

Nov. 1, 2021

Availability

Academic Institutions and Nonprofits only

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pRRL_LYSET_Y34X

Plasmid

#246084

Purpose

Stable expression of LYSET Y34X (isoform 2; Y72X in isoform 1)

Depositor

Wilhelm Palm

Article

Pechincha et al Science. 2022 Oct 7;378(6615):eabn5637.

Insert

LYSET Y34X (LYSET Human)

Use

Lentiviral

Expression

Mammalian

Promoter

UBC

Available Since

Dec. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pRRL_LYSET

Plasmid

#246082

Purpose

Stable expression of LYSET (isoform 2)

Depositor

Wilhelm Palm

Article

Pechincha et al Science. 2022 Oct 7;378(6615):eabn5637.

Insert

LYSET (LYSET Human)

Use

Lentiviral

Expression

Mammalian

Promoter

UBC

Available Since

Nov. 26, 2025

Availability

Academic Institutions and Nonprofits only

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pRRL_LYSET_R7W

Plasmid

#246083

Purpose

Stable expression of LYSET R7W (isoform 2; R45W in isoform 1)

Depositor

Wilhelm Palm

Article

Pechincha et al Science. 2022 Oct 7;378(6615):eabn5637.

Insert

LYSET R7W (LYSET Human)

Use

Lentiviral

Expression

Mammalian

Promoter

UBC

Available Since

Nov. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pSA358_pAAV-SCP1-Intron-eGFP-CS1

Plasmid

#215513

Purpose

Single stranded AAV eGFP reporter vector with SCP1 promoter.

Depositor

Stein Aerts

Article

Hecker et al Science. 2025 Jan 2;387(6735):eadp3957.

Insert

eGFP

Use

AAV

Expression

Mammalian

Promoter

SCP1

Available Since

Aug. 12, 2025

Availability

Academic Institutions and Nonprofits only

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ku70 insUP+ pXYL-G418-tNOS-pADH2-crtE-tNOS-pXYL-crtI-tNOS-pGPD-crtYB-tNOS+ku70 insD (SBE146)

Plasmid

#195048

Purpose

cassette for the deletion of ku70 and overexpression of crtE, crtI, and crtYB under different combination of promoters

Depositor

Petri-Jaan Lahtvee

Article

Bonturi et al Metab Eng Commun. 2022 May 23;15:e00200.

Inserts

crtE
crtI
crtYB

Expression

Yeast

Promoter

pADH2, pGPD, and pXYL

Available Since

Nov. 21, 2023

Availability

Academic Institutions and Nonprofits only

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ku70 insUP+ pXYL-G418-tNOS-pADH2-crtE-tNOS-pGPD-crtI-tNOS-pXYL-crtYB-tNOS+ku70 insD (SBE145)

Plasmid

#195047

Purpose

cassette for the deletion of ku70 and overexpression of crtE, crtI, and crtYB under different combination of promoters

Depositor

Petri-Jaan Lahtvee

Article

Bonturi et al Metab Eng Commun. 2022 May 23;15:e00200.

Inserts

crtE
crtI
crtYB

Expression

Yeast

Promoter

pADH2, pGPD, and pXYL

Available Since

Nov. 21, 2023

Availability

Academic Institutions and Nonprofits only

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ku70 insUP+ pXYL-G418-tNOS-pXYL-crtE-tNOS-pGPD-crtI-tNOS-pADH2-crtYB-tNOS+ku70 insD (SBE144)

Plasmid

#195046

Purpose

cassette for the deletion of ku70 and overexpression of crtE, crtI, and crtYB under different combination of promoters

Depositor

Petri-Jaan Lahtvee

Article

Bonturi et al Metab Eng Commun. 2022 May 23;15:e00200.

Inserts

crtE
crtI
crtYB

Expression

Yeast

Promoter

pADH2, pGPD, and pXYL

Available Since

Nov. 21, 2023

Availability

Academic Institutions and Nonprofits only

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330-BFP-hCYP3A4-enhancer-R-sgRNA

Plasmid

#176841

Purpose

Targeting human CYP3A4 proximal enhancer right boundary. sgRNA expressing cells could be FACS sorted by BFP expression.

Depositor

Rudolf Jaenisch

Article

Ma et al Cell Stem Cell. 2022 Apr 13. pii: S1934-

Insert

Human CYP3A4 proximal enhancer right boundary

Expression

Mammalian

Promoter

U6

Available Since

Nov. 2, 2021

Availability

Academic Institutions and Nonprofits only

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