We narrowed to 20,245 results for: ACE;

1. pENTR-TMEM144

   Plasmid

   #221426

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   TMEM144 (TMEM144 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pENTR-Sensor_P2A_SLC2A4

   Plasmid

   #221429

   Purpose

   Gateway entry clone encoding a polyprotein that is cleaved to FRET glucose sensor and SLC2A4 proteins

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   Sensor_P2A_SLC2A4 (SLC2A4 Synthetic)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pLKO.1 mTagBFP2 rat DJ-1 shRNA

   Plasmid

   #222870

   Purpose

   Expresses mTagBFP2 along with an shRNA against rat DJ-1

   Depositor

   Timothy Ryan

   Article

   Kokotos et al Sci Adv. 2024 Aug 23;10(34):eadn6016. do

   Insert

   DJ-1 shRNA (Park7 Rat)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   July 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pEGFP-SET-EMD (N-SET-EMD)

   Plasmid

   #217765

   Purpose

   Fluorescent reporter for ceramide (putative, mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   SET (SET Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   EMD domain (aa 70-226)

   Promoter

   CMV

   Available Since

   June 12, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

5. pSET-EMD-EGFP (C-SET-EMD)

   Plasmid

   #217764

   Purpose

   Fluorescent reporter for ceramide (putative, mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   SET (SET Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   EMD domain (aa 70-226)

   Promoter

   CMV

   Available Since

   June 12, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

6. pNES-PRKCZ-C20-EGFP (C-NES-PRKCZ-C20)

   Plasmid

   #217763

   Purpose

   Fluorescent reporter for ceramide (putative, mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   Protein kinase C zeta (PRKCZ Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   NES (ALQKKLEELELDEAPVAT) plus C20 domain (aa 405-…

   Promoter

   CMV

   Available Since

   June 11, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

7. pEGFP-KSR1-CA3 (N-KSR)

   Plasmid

   #217755

   Purpose

   Fluorescent reporter for glucosyl-ceramide (putative, mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   Kinase suppressor of ras 1 CA3 domain (KSR1 Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   CA3 domain aa 317-400

   Promoter

   CMV

   Available Since

   June 11, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

8. pKSR1-CA3-GS-mRFP1 (C-KSR-GS)

   Plasmid

   #217758

   Purpose

   Fluorescent reporter for ceramide (mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   Kinase suppressor of ras 1 CA3 domain (KSR1 Human)
   

   Use

   Tags

   mRFP

   Expression

   Mammalian

   Mutation

   CA3 domain aa 317-400 with GGSSGGGGA linker

   Promoter

   CMV

   Available Since

   June 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pKSR1-CA3-GS-EGFP (C-KSR-GS)

   Plasmid

   #217757

   Purpose

   Fluorescent reporter for ceramide (mammalian expression)

   Depositor

   Paula Nunes-Hasler

   Article

   Girik et al Int J Mol Sci. 2024 Mar 5;25(5):2996. do

   Insert

   Kinase suppressor of ras 1 CA3 domain (KSR1 Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   CA3 domain aa 317-400 with GGSSGGGGA linker

   Promoter

   CMV

   Available Since

   June 10, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

10. psiCHECK-VIM270-pSM

    Plasmid

    #215871

    Purpose

    This plasmid encodes luciferaase which has siRNA binding sites in 3'UTR for detecting the knockdown efficiency of siRNA.

    Depositor

    Kumiko Ui-Tei

    Article

    Iribe et al ACS Omega. 2017 May 31;2(5):2055-2064. d

    Insert

    3 tandem repeats of target site (complementary to seed seq of passenger strand of siRNA for VIM) is inserted to 3'UTR of RLuc (VIM Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    May 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. LacI pm

    Plasmid

    #218097

    Purpose

    Phagemid that expresses LacI but no phage proteins, used as a control

    Depositor

    Kevin Esvelt

    Type

    Empty backbone

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. 5'-BirA-FLAG Chtop-exon minimal CMV pCDNA5

    Plasmid

    #212090

    Purpose

    LR vector for integration of Chtop-exon into N2a FRT rtTA3 expression cells (BioID vector)

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Chtop-exon (Chtop Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. 5'-3xFLAG Camta2-exon minimal CMV pCDNA5

    Plasmid

    #212048

    Purpose

    LR vector for integration of Camta2-exon into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Camta2-exon (Camta2 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. 5'-3xFLAG Camta2+exon minimal CMV pCDNA5

    Plasmid

    #212049

    Purpose

    LR vector for integration of Camta2+exon(21nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Camta2+exon(21nt) (Camta2 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. 5'-3xFLAG L3mbtl3+exon minimal CMV pCDNA5

    Plasmid

    #212059

    Purpose

    LR vector for integration of L3mbtl3+exon(75nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    L3mbtl3+exon(75nt) (L3mbtl3 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. 5'-3xFLAG Chtop+exon_siResist minimal CMV pCDNA5

    Plasmid

    #212083

    Purpose

    LR vector for integration of Chtop+exon(138nt)_siResist into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Chtop+exon(138nt)_siResist (Chtop Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    GCCTATATGTCCAAGACCA

    Promoter

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. 5'-3xFLAG Chtop+exon minimal CMV pCDNA5

    Plasmid

    #212081

    Purpose

    LR vector for integration of Chtop+exon(138nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Chtop+exon(138nt) (Chtop Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. 5'-3xFLAG Chtop-exon_siResist minimal CMV pCDNA5

    Plasmid

    #212082

    Purpose

    LR vector for integration of Chtop-exon_siResist into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Chtop-exon_siResist (Chtop Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    GCCTATATGTCCAAGACCA

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. 5'-3xFLAG Med24-exon minimal CMV pCDNA5

    Plasmid

    #212060

    Purpose

    LR vector for integration of Med24-exon into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Med24-exon (Med24 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. 5'-3xFLAG Kansl3-exon minimal CMV pCDNA5

    Plasmid

    #212052

    Purpose

    LR vector for integration of Kansl3-exon into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Kansl3-exon (Kansl3 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. 5'-3xFLAG Kansl3+exon minimal CMV pCDNA5

    Plasmid

    #212053

    Purpose

    LR vector for integration of Kansl3+exon(78nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Kansl3+exon(78nt) (Kansl3 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. 5'-3xFLAG Gse1+exon minimal CMV pCDNA5

    Plasmid

    #212057

    Purpose

    LR vector for integration of Gse1+ex(108nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Gse1+ex(108nt) (Gse1 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. 5'-3xFLAG Kdm1a+exon minimal CMV pCDNA5

    Plasmid

    #212055

    Purpose

    LR vector for integration of Kdm1a+exon(12nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Kdm1a+exon(12nt) (Kdm1a Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. 5'-3xFLAG Med24+exon minimal CMV pCDNA5

    Plasmid

    #212061

    Purpose

    LR vector for integration of Med24+exon(57nt) into N2a FRT rtTA3 expression cells

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Med24+exon(57nt) (Med24 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. 5'-BirA-FLAG Kdm1a-exon minimal CMV pCDNA5

    Plasmid

    #212088

    Purpose

    LR vector for integration of Kdm1a-exon into N2a FRT rtTA3 expression cells (BioID vector)

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Kdm1a-exon (Kdm1a Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. 5'-BirA-FLAG Kdm1a+exon minimal CMV pCDNA5

    Plasmid

    #212089

    Purpose

    LR vector for integration of Kdm1a+exon(12nt) into N2a FRT rtTA3 expression cells (BioID vector)

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Kdm1a+exon(12nt) (Kdm1a Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. 5'-BirA-FLAG Chtop+exon minimal CMV pCDNA5

    Plasmid

    #212091

    Purpose

    LR vector for integration of Chtop+exon(138nt) into N2a FRT rtTA3 expression cells (BioID vector)

    Depositor

    Benjamin Blencowe

    Article

    Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

    Insert

    Chtop+exon(138nt) (Chtop Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Jan. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pAAV-CMV-FLEX-SaCas9-U6-sgFAAH

    Plasmid

    #209197

    Purpose

    Mutagenesis of Faah

    Depositor

    Larry Zweifel

    Article

    Balsevich et al Elife. 2023 Apr 11;12:e81919. doi: 10.75

    Insert

    Faah (Faah Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available Since

    Jan. 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. Bn R52A, R54A pMT2

    Plasmid

    #206087

    Purpose

    Cav2.2 N-terminus (amino acids 1-95) with R52A and R54A mutations that prevent dominant-negative suppression of Cav2.2 currents by truncated Cav2.2

    Depositor

    Annette Dolphin

    Article

    Page et al J Biol Chem. 2010 Jan 8;285(2):835-44. d

    Insert

    cacna1b (CACNA1B Rabbit)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    R52A, R54A

    Promoter

    Ad MLP/TPL/SV40

    Available Since

    Nov. 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. An HA CAAX pMT2

    Plasmid

    #206116

    Purpose

    expression of Cav2.1 N-terminus (amino acids 1-100) with a C-terminal CAAX (last 10aa of H.Ras) motif and a HA tag

    Depositor

    Annette Dolphin

    Article

    Page et al J Biol Chem. 2010 Jan 8;285(2):835-44. d

    Insert

    cacna1a (Cacna1a Rat)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Ad MLP/TPL/SV40

    Available Since

    Nov. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge