We narrowed to 23,460 results for: c-myc

1. pScalps_puro_mIL-2Rα ST

   Plasmid

   #59919

   Purpose

   Expresses mouse interleukin-2 receptor alpha chain mutated

   Depositor

   Silvia Monticelli

   Article

   Deho' et al J Immunol. 2014 Sep 1;193(5):2196-206. d

   Insert

   interleukin 2 receptor alpha (Il2ra Mouse)
   

   Use

   Lentiviral

   Mutation

   changed sequence of the intracellular (C-terminal…

   Available Since

   Oct. 3, 2014

   Availability

   Academic Institutions and Nonprofits only

2. pcDNA3-H-Ras_V12-E38

   Plasmid

   #39507

   Depositor

   Julian Downward

   Article

   Rodriguez-Viciana et al Cell. 1997 May 2;89(3):457-67.

   Insert

   HRAS V12 E38 (HRAS Human)
   

   Expression

   Mammalian

   Mutation

   G12V and D38E

   Promoter

   CMV

   Available Since

   Aug. 15, 2012

   Availability

   Academic Institutions and Nonprofits only

3. sgKRAS(B)

   Plasmid

   #85567

   Purpose

   Expresses sgRNA targeting human KRAS around codon G12

   Depositor

   Luca Grumolato

   Article

   Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

   Insert

   KRAS proto-oncogene, GTPase (KRAS Human)
   

   Expression

   Mammalian

   Available Since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

4. sgKRAS(A)

   Plasmid

   #85566

   Purpose

   Expresses sgRNA targeting human KRAS around codon G12

   Depositor

   Luca Grumolato

   Article

   Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

   Insert

   KRAS proto-oncogene, GTPase (KRAS Human)
   

   Expression

   Mammalian

   Available Since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

5. JDW 742 (pDONR221-EGFP-KRAS4B-G12V)

   Plasmid

   #156403

   Purpose

   Gateway middle entry clone encoding EGFP-fused to human KRAS4B with G12V mutation, includes a stop codon

   Depositor

   Joshua Wythe

   Article

   Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

   Insert

   human mutant KRAS4B-G12V (KRAS Human)
   

   Use

   Gateway cloning

   Tags

   EGFP

   Mutation

   mutant KRAS4B-G12V

   Available Since

   Aug. 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pcDNA3.1(+) Laccase2 MCS-mFndc3b

   Plasmid

   #126443

   Purpose

   Expresses mouse Fndc3b circular RNA

   Depositor

   Jeremy Wilusz

   Article

   Garikipati et al Nat Commun. 2019 Sep 20;10(1):4317. doi:

   Insert

   Fndc3b (Fndc3b Mouse)
   

   Expression

   Mammalian

   Mutation

   circFndc3b exons are separated by a miniature int…

   Promoter

   CMV

   Available Since

   Sept. 30, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. JDW 823 (pDONR221-V5-mScarlet-I-hsKRAS4A-G12V)

   Plasmid

   #156406

   Purpose

   Gateway middle entry clone encoding V5-tagged mScarlet-I-fused to human KRAS4A with G12V mutation, includes a stop codon

   Depositor

   Joshua Wythe

   Article

   Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

   Insert

   human mutant KRAS4A-G12V (KRAS Human)
   

   Use

   Gateway cloning

   Tags

   mScarlet-I

   Mutation

   mutant KRAS4A-G12V

   Available Since

   Aug. 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pcDNA3.1-GSDMD_1-270

   Plasmid

   #218229

   Purpose

   Gasdermin1-270 is a pore-forming GSDMD formed by SARS-CoV-2 3CLpro cleavage. Transfection in HEK293 cells showed GSDMD 1-270 pores secrete 3CLpro, nucleocapsid, and in excess, kill cells by pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 1-270

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

9. pcDNA3.1-GSDMD_1-275

   Plasmid

   #218230

   Purpose

   Gasdermin-D_1-275 is a pore-forming GSDMD formed by cleavage by host caspases. Transfection in HEK293 cells showed GSDMD 1-275 pores secrete 3CLpro, nucleocapsid; in excess, kills cells by pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 1-275

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

10. pcDNA3.1-GSDMD_29-484

    Plasmid

    #218231

    Purpose

    Gasdermin-D_29-484 is a non-functional GSDMD formed by SARS-CoV-2 3CLpro cleavage in the N-terminal domain. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 29-484

    Available Since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. pcDNA3.1-GSDMD_29-270

    Plasmid

    #218232

    Purpose

    Gasdermin-D_29-270 is a non-functional GSDMD formed by two SARS-CoV-2 3CLpro cleavages. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 29-270

    Available Since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

12. pLV-PB2_Lock1-I436C+S993C

    Plasmid

    #182879

    Purpose

    Lentivirus for expression of Plexin-B2 locked ring mutant

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

    Insert

    hPLXNB2 (PLXNB2 Human)
    

    Use

    Lentiviral

    Mutation

    changed Isoleucine 436 to Cysteine and Serine 993…

    Available Since

    Jan. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLV-PB2_Lock2-I436C+T1051C

    Plasmid

    #182880

    Purpose

    Lentivirus for expression of Plexin-B2 locked ring mutant

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

    Insert

    hPLXNB2 (PLXNB2 Human)
    

    Use

    Lentiviral

    Mutation

    changed Isoleucine 436 to Cysteine and Threonine …

    Available Since

    Jan. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pEF2-EFGR-hTyro

    Plasmid

    #225998

    Purpose

    Expresses a chimeric construct having N-terminal human EGFR and C-terminal human Tyro3

    Depositor

    Sergei Kotenko, Raymond Birge

    Article

    Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

    Insert

    human EGFR N-Terminal human Tyro3 C-Terminal Fusion (EGFR, TYRO3 Human)
    

    Expression

    Mammalian

    Promoter

    EF1-a

    Available Since

    Nov. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. JDW 832 (pDONR221-V5-mTagBFP2-KRAS4A-G12D)

    Plasmid

    #156404

    Purpose

    Gateway middle entry clone encoding V5-tagged mTagBFP2-fused to human KRAS4A with G12D mutation, includes a stop codon

    Depositor

    Joshua Wythe

    Article

    Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

    Insert

    human mutant KRAS4A-G12D (KRAS Human)
    

    Use

    Gateway cloning

    Tags

    mTagBFP2

    Mutation

    mutant KRAS4A-G12D

    Available Since

    Aug. 18, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pMT646 human L1 ORF2p-3xFlag (ORFeus-Hs, CMV promoter) in pCEP4 Puro

    Plasmid

    #213026

    Purpose

    Expresses full length human LINE-1 in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2

    Depositor

    Martin S. Taylor

    Article

    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:

    Insert

    Human LINE-1 (ORFeus-Hs codon optimized sequence) with ORF2-3xFlag
    

    Tags

    3xFlag (ORF2p)

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLD564 human L1 ORF2p-3xFlag (L1RP, CMV promoter) in pCEP4 Puro

    Plasmid

    #213030

    Purpose

    Expresses full length human LINE-1 in human cells (native L1RP sequence), with a C-terminal 3xFlag tag on ORF2

    Depositor

    Martin S. Taylor

    Article

    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:

    Insert

    Human LINE-1 (L1RP Sequence) with 5' UTR and ORF2-3xFlag
    

    Tags

    3xFlag (ORF2p)

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. (114) pcDNA3.1-GFP-Flag-JunB-EPEA

    Plasmid

    #160743

    Purpose

    Expresses a GFP tagged JunB with Flag and EPEA tags.

    Depositor

    Christina Woo

    Article

    Ramirez et al ACS Chem Biol. 2020 Apr 17;15(4):1059-10

    Insert

    GFP-Flag-JunB-EPEA (JUN Human)
    

    Tags

    EPEA, Flag, and GFP

    Expression

    Mammalian

    Promoter

    T7/CMV

    Available Since

    May 18, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. YES1 gRNA (BRDN0001148961)

    Plasmid

    #77967

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human YES1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    YES1 (YES1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. YES1 gRNA (BRDN0001145317)

    Plasmid

    #77965

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human YES1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    YES1 (YES1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge