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pCR8-CHD5-FRAGMENT

Plasmid

#68879

Purpose

GW entry vector for CHD5

Depositor

Adrian Bracken

Article

Egan et al Dev Cell. 2013 Aug 12;26(3):223-36. doi:

Insert

CHD5 (CHD5 Human)

Use

Gateway entry vector

Mutation

331-672aa

Promoter

none

Available Since

Nov. 16, 2015

Availability

Academic Institutions and Nonprofits only
pLJM5-I560S-mDPYD

Plasmid

#61615

Purpose

The mouse Dpyd was used to rescue the human DPYD hairpin affect on EMT

Depositor

David Sabatini

Article

Shaul et al Cell. 2014 Aug 28;158(5):1094-109. doi:

Insert

Dihydropyrimidine dehydrogenase (Dpyd Mouse)

Expression

Mammalian

Mutation

Changed Isoleucine at position 560 to Serine

Promoter

CMV

Available Since

Jan. 20, 2015

Availability

Academic Institutions and Nonprofits only

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AAV-hT7

Plasmid

#252215

Purpose

AAV6 capsid variant evolved

Depositor

Justin Eyquem

Article

Nyberg et al Nature. 2026 Mar 18. doi: 10.1038/s41586

Insert

AAV-hT7 rep/cap

Use

AAV

Available Since

April 30, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-HA SIRT7

Plasmid

#246167

Purpose

Used for transfection of cells for expression N-HA SIRT7

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

SIRT7 (SIRT7 Human)

Tags

HA

Expression

Mammalian

Available Since

April 27, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-HA SIRT4

Plasmid

#246164

Purpose

Used for transfection of cells for expression N-HA SIRT4

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

SIRT4 (SIRT4 Human)

Tags

HA

Expression

Mammalian

Available Since

April 27, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-HA SIRT3

Plasmid

#246163

Purpose

Used for transfection of cells for expression N-HA SIRT3

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

SIRT3 (SIRT3 Human)

Tags

HA

Expression

Mammalian

Available Since

April 27, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-HA SIRT2

Plasmid

#246162

Purpose

Used for transfection of cells for expression N-HA SIRT2

Depositor

Sheng-cai Lin

Article

Qu et al Nature. 2024 Dec 18. doi: 10.1038/s41586

Insert

SIRT2 (SIRT2 Human)

Tags

HA

Expression

Mammalian

Available Since

April 27, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-ePiv (CJT553)

Plasmid

#248215

Purpose

ePiv invertase, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

ePiv invertase

Use

CRISPR; In vitro transcription

Expression

Mammalian

Mutation

ePiv(E257R, E285R, T290R)

Promoter

CMV and T7

Available Since

April 16, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-bpNLS-IS621 (CJT489)

Plasmid

#248213

Purpose

bpNLS-tagged IS621 bridge recombinase, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

bpNLS-IS621

Use

CRISPR; In vitro transcription

Tags

BPNLS

Expression

Mammalian

Mutation

None

Promoter

CMV and T7

Available Since

April 16, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-bpNLS-Bxb1 (EMK569)

Plasmid

#248208

Purpose

Bxb1 recombinase with N-terminal bpNLS, expressed from a CMV promoter.

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

bpNLS-Bxb1

Use

CRISPR; In vitro transcription

Tags

BPNLS

Expression

Mammalian

Mutation

None

Promoter

CMV and T7

Available Since

April 15, 2026

Availability

Academic Institutions and Nonprofits only

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