Addgene

We narrowed to 1,461 results for: p53

Showing: 1121 - 1140 of 1461 results

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IFI16-(192-393)-HinA-E272A

Plasmid

#35057

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(192-393)-HinA (IFI16 Human)

Use

Tags

His

Expression

Mutation

Contains HinA domain: aa 192-393; E272A mutation

Promoter

T7

Available since

April 6, 2012

Availability

Academic Institutions and Nonprofits only
IFI16-(192-393)-HinA-E222A

Plasmid

#35056

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(192-393)-HinA (IFI16 Human)

Use

Tags

His

Expression

Mutation

Contains HinA domain: aa 192-393; E222A mutation

Promoter

T7

Available since

April 4, 2012

Availability

Academic Institutions and Nonprofits only
IFI16-(192-393)-HinA-T220A

Plasmid

#35055

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(192-393)-HinA (IFI16 Human)

Use

Tags

His

Expression

Mutation

Contains HinA domain: aa 192-393; T220A mutation

Promoter

T7

Available since

April 4, 2012

Availability

Academic Institutions and Nonprofits only
IFI16-(192-393)-HinA-Y218A

Plasmid

#35054

Depositor

Cheryl Arrowsmith

Article

Liao et al Structure. 2011 Mar 9;19(3):418-29.

Insert

IFI16-(192-393)-HinA (IFI16 Human)

Use

Tags

His

Expression

Mutation

Contains HinA domain: aa 192-393; Y218A mutation

Promoter

T7

Available since

April 4, 2012

Availability

Academic Institutions and Nonprofits only
pET28-His-TEV-NQO1

Plasmid

#119058

Purpose

For expression in E.coli and affinity purification of N-terminally His tagged NQO1

Depositor

Yosef Shaul

Article

Tsvetkov et al Proc Natl Acad Sci U S A. 2005 Apr 12;10

Insert

NAD(P)H dehydrogenase, quinone 1 (NQO1) (NQO1 Human)

Use

Tags

6His, TEV site

Expression

Bacterial

Mutation

Promoter

T7

Available since

Dec. 20, 2018

Availability

Academic Institutions and Nonprofits only

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pcDNA4/TO-HRASG12V

Plasmid

#216509

Purpose

Expresses HRAS with a G12V point mutation in human cells under a tetracycline/doxycycline-inducible promoter

Depositor

John Diffley

Article

Zeng et al Cell. 2023 Feb 2;186(3):528-542.e14. doi

Insert

HRAS (HRAS Human)

Use

Tags

HA

Expression

Mammalian

Mutation

G12V

Promoter

Available since

April 12, 2024

Availability

Academic Institutions and Nonprofits only

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pRetroX GFP T2A Cre

Plasmid

#63704

Purpose

Inducible expression of GFP T2A Cre fusion in mammalian cells

Depositor

Floris Foijer

Article

Foijer et al Proc Natl Acad Sci U S A. 2014 Sep 16;11

Insert

T2A Cre

Use

Retroviral

Tags

EGFP

Expression

Mammalian

Mutation

Promoter

tight TRE promoter

Available since

April 22, 2015

Availability

Academic Institutions and Nonprofits only

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WWP-Luc (p21/WAF1 promoter)

Plasmid

#16451

Depositor

Bert Vogelstein

Article

el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

Insert

WAF1 promoter (CDKN1A Human)

Use

Luciferase

Tags

luciferase

Expression

Mammalian

Mutation

Promoter

Available since

June 11, 2008

Availability

Academic Institutions and Nonprofits only

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pCI-Neo-HKIImut

Plasmid

#99240

Purpose

Type II Hexokinase expressed in AS-30D rat hepatoma cell line

Depositor

Peter Pedersen

Article

Mathupala et al J Biol Chem. 1997 Sep 5;272(36):22776-80

Insert

Hexokinase II (Hk2 Rat)

Use

Tags

Expression

Mammalian

Mutation

Four silent mutations; P (115)L, A (192) V, F (78…

Promoter

CMV I.E.

Available since

Aug. 30, 2017

Availability

Academic Institutions and Nonprofits only

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LentiGuidPuro-hTP73_sgRNA-1

Plasmid

#88855

Purpose

CRISPR KO of Trp73

Depositor

Joan Massague

Article

Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

Insert

Trp73

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

July 11, 2017

Availability

Academic Institutions and Nonprofits only

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MSCV-miR-34a

Plasmid

#63932

Purpose

MSCV vector for overexpressing mouse miR-34

Depositor

Lin He

Article

Okada et al Genes Dev. 2014 Mar 1;28(5):438-50. doi:

Insert

microRNA 34a (Mir34a Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 11, 2015

Availability

Academic Institutions and Nonprofits only

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TOP2A sgRNA1

Plasmid

#138190

Purpose

3rd generation lentiviral gRNA plasmid targeting human TOP2A

Depositor

Wen Xue

Article

Kwan et al Hepatology. 2019 Jun 12. doi: 10.1002/he

Insert

TOP2A (TOP2A Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

March 18, 2020

Availability

Academic Institutions and Nonprofits only

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TOP2A sgRNA2

Plasmid

#138191

Purpose

3rd generation lentiviral gRNA plasmid targeting human TOP2A

Depositor

Wen Xue

Article

Kwan et al Hepatology. 2019 Jun 12. doi: 10.1002/he

Insert

TOP2A (TOP2A Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

March 18, 2020

Availability

Academic Institutions and Nonprofits only

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LentiGuidPuro-hTP63_sgRNA-1

Plasmid

#88854

Purpose

CRISPR KO of Trp63

Depositor

Joan Massague

Article

Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

Insert

Trp63

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

July 11, 2017

Availability

Academic Institutions and Nonprofits only

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pLVXT-mWnt3

Plasmid

#121934

Purpose

doxycycline-inducible mouse Wnt3

Depositor

Joan Massague

Article

Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

Insert

Wnt3 (Wnt3 Mouse)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Feb. 15, 2019

Availability

Academic Institutions and Nonprofits only

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lenti-SAM-hygro

Plasmid

#138955

Purpose

Lentiviral vector for co-expressing spCas9, dRNA-MS2, p65 and HSF1 fused to MS2 binding protein, and hygromycin resistance gene

Depositor

Nadya Dimitrova

Article

Olivero et al Mol Cell. 2020 Feb 20;77(4):761-774.e8.

Type

Empty backbone

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6 AND EF1a

Available since

Aug. 28, 2020

Availability

Academic Institutions and Nonprofits only

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T7-p73DD L371P-pcDNA3

Plasmid

#23049

Depositor

William Kaelin

Article

Irwin et al Nature. 2000 Oct 5. 407(6804):645-8.

Insert

tumor protein p73 (TP73 Human)

Use

Tags

T7

Expression

Mammalian

Mutation

truncated cDNA encodes truncated protein (aa 327-…

Promoter

Available since

Jan. 28, 2010

Availability

Academic Institutions and Nonprofits only

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pMKO.1 puro-luc (shRNA)

Plasmid

#153962

Purpose

Expresses a shRNA against firefly luciferase

Depositor

Hiroyuki Konishi

Article

Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7

Insert

shRNA against firefly luciferase (19-bp-long target)

Use

Luciferase, RNAi, and Retroviral

Tags

N/A

Expression

Mammalian

Mutation

Promoter

U6 promoter

Available since

July 21, 2020

Availability

Academic Institutions and Nonprofits only

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Bnip3L RNAi pSuper-retro

Plasmid

#17468

Depositor

Wafik El-Deiry

Article

Fei et al Cancer Cell. 2004 Dec . 6(6):597-609.

Insert

Bnip3L RNAi (BNIP3L Human)

Use

RNAi and Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

March 27, 2008

Availability

Academic Institutions and Nonprofits only
MSCV-Fbxo7(ΔF-box)-IRES-GFP

Plasmid

#171787

Purpose

retrovirus production

Depositor

Heike Laman

Article

Lomonosov et al PLoS One. 2011;6(6):e21165. doi: 10.1371

Insert

Fbxo7 isoform 1 (FBXO7 Human)

Use

Retroviral

Tags

Expression

Mutation

deletion of aa335-367

Promoter

Available since

Jan. 31, 2022

Availability

Academic Institutions and Nonprofits only

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