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TDP-43_CTD_F316A

Plasmid

#248870

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with F316A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_F316A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed F316A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_M337A

Plasmid

#248885

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with M337A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M337A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M337A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_M339A

Plasmid

#248886

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with M339A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M339A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M339A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_L340A

Plasmid

#248887

Purpose

Edit Expresses 6xHis-tagged C-terminal domain of TDP-43 with L340A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_L340A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed L340A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_S342A

Plasmid

#248888

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with S342A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S342A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed S342A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_M336A

Plasmid

#248884

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with M336A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M336A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M336A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_S333A

Plasmid

#248882

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with S333A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S333A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed S333A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43_CTD_W334A

Plasmid

#248883

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with W334A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_W334A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed W334A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pTRIP-SFFV-EGFP-FLAG-UL36USP (C40)

Plasmid

#235548

Purpose

To express GFP-FLAG-UL36USP (C40) - region 25-520 of UL36

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

UL36USP (C40)

Use

Lentiviral

Tags

EGFP-FLAG

Mutation

N-terminal part of UL36 starting at the second AT…

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

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pTRIP-SFFV-EGFP-FLAG-UL36USP (C65)

Plasmid

#235549

Purpose

To express GFP-FLAG-UL36USP (C65) - region 1-520 of UL36

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

UL36USP (C65)

Use

Lentiviral

Tags

EGFP-FLAG

Mutation

N-terminal part of UL36 starting at the first ATG…

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLKO.1-puro-USP7-sh1

Plasmid

#235527

Purpose

shRNA against human USP7

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

USP7 (USP7 Human)

Use

Lentiviral

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLKO.1-puro-USP7-sh5

Plasmid

#235528

Purpose

shRNA against human USP7

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

USP7 (USP7 Human)

Use

Lentiviral

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pTRIP-SFFV-tagBFP-2A-coICP0-∆USP7

Plasmid

#235540

Purpose

To express tagBFP-2A-coICP0-∆USP7 (ICP0 ∆618-633, co = codon-optimized)

Depositor

Nicolas Manel

Article

Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

Insert

ICP0-∆USP7

Use

Lentiviral

Mutation

Deletion of region ∆618-633.

Available Since

July 17, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
FUS LC 4QQ->AA

Plasmid

#226600

Purpose

4 glutamine pairs to alanine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

Depositor

Nicolas Fawzi

Article

Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

Insert

FUS LC 4QQ->AA (FUS Human)

Tags

6His

Expression

Bacterial

Mutation

4 QQ pairs replaced with AA pairs at positions 27…

Promoter

T7

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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FUS LC 4QQ->GG

Plasmid

#226601

Purpose

4 glutamine pairs to glycine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

Depositor

Nicolas Fawzi

Article

Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

Insert

FUS LC 4QQ->GG (FUS Human)

Tags

6His

Expression

Bacterial

Mutation

4 QQ pairs replaced with GG pairs at positions 27…

Promoter

T7

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
FUS LC 4QQ->NN

Plasmid

#226602

Purpose

4 glutamine pairs to asparagine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

Depositor

Nicolas Fawzi

Article

Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

Insert

FUS LC 4QQ->NN (FUS Human)

Tags

6His

Expression

Bacterial

Mutation

4 glutamine pairs to asparagine pairs at position…

Promoter

T7

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
TDP-43 _CTD_5A→M_IDR + 5M→A_CR

Plasmid

#194268

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with TDP-43 _CTD_5A→M_IDR + 5M→A_CR

Depositor

Nicolas Fawzi

Article

Mohanty et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

Insert

TDP-43 (TARDBP Synthetic, Human)

Tags

6XHistag

Expression

Bacterial

Mutation

A297M, A367M, A381M, A388M, A391M M322A, M323A, M…

Promoter

T7

Available Since

Oct. 26, 2023

Availability

Academic Institutions and Nonprofits only

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MBP-hnRNPA2_LC_R191K_R201K_R216K_R254K

Plasmid

#104467

Purpose

express MBP hnRNPA2 LC with 4 R to K mutations

Depositor

Nicolas Fawzi

Article

Ryan et al Mol Cell. 2018 Jan 17. pii: S1097-2765(1

Insert

hnRNPA2 (HNRNPA2B1 Human)

Tags

His-MBP

Expression

Bacterial

Mutation

R191K R201K R216K R254K

Available Since

Jan. 18, 2018

Availability

Academic Institutions and Nonprofits only

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pCAR-IF reporter

Plasmid

#16628

Depositor

Bert Vogelstein

Article

Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41.

Insert

CAR-IF

Tags

beta-galactosidase

Expression

Mammalian

Available Since

March 12, 2008

Availability

Academic Institutions and Nonprofits only
pCAR-OF reporter

Plasmid

#16627

Depositor

Bert Vogelstein

Article

Nicolaides et al Mol Cell Biol. 1998 Mar . 18(3):1635-41.

Insert

CAR-OF

Tags

beta-galactosidase

Expression

Mammalian

Available Since

March 12, 2008

Availability

Academic Institutions and Nonprofits only