2,294 results

1. pGL3-MTS-ND6-W82-R15-G1333C-UGI-Puro

   Plasmid

   #198861

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND6) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   ND6-W82-R15 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pGL3-MTS-ND5-W68-R15-G1333N-UGI-Puro

   Plasmid

   #198859

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND5) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   ND5-W68-R15 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pGL3-MTS-ND4-W24-R17-G1333N-UGI-Puro

   Plasmid

   #198857

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND4) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   ND4-W24-R17 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pGL3-MTS-ND3-Q26-R19-G1397N-UGI-Puro

   Plasmid

   #198855

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND3) by swapping Gln codon CAA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   ND3-Q26-R19 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pGL3-MTS-ND2-W30-R18-G1333N-UGI-Puro

   Plasmid

   #198853

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND2) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   ND2-W30-R18 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pGL3-MTS-CYTB-W77-R14-G1333N-UGI-Puro

   Plasmid

   #198849

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(CYTB) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   CYTB-W77-R14 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pGL3-MTS-COX3-W16-R15-G1333N-UGI-Puro

   Plasmid

   #198847

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(COX3) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   COX3-W16-R15 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pGL3-MTS-COX2-Q6-R18-G1333C-UGI-Puro

   Plasmid

   #198845

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(COX2) by swapping Gln codon CAA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   COX2-Q6-R18 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pGL3-MTS-COX1-W25-R18-G1333N-UGI-Puro

   Plasmid

   #198843

   Purpose

   Employ DdCBE-mediated mtDNA editing to ablate mtProtein(COX1) by swapping Trp codon TGA with stop codon TAA in C6 cells

   Depositor

   Bin Shen

   Article

   Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

   Insert

   COX1-W25-R18 TALEN
   

   Expression

   Mammalian

   Available Since

   May 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pGL3-MTS-ATP8-W9-R15-G1333N-UGI-Puro

    Plasmid

    #198841

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ATP8) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ATP8-W9-R15 TALEN
    

    Expression

    Mammalian

    Available Since

    May 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pGL3-MTS-ATP6-W68-R17-G1333N-UGI-Puro

    Plasmid

    #198839

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ATP6) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ATP6-W68-R17 TALEN
    

    Expression

    Mammalian

    Available Since

    May 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pLJM1-Lamp1 FLAG

    Plasmid

    #199750

    Purpose

    Lentiviral construct to stably express Lamp1

    Depositor

    Roberto Zoncu

    Article

    Shin et al Science. 2022 Sep 16;377(6612):1290-1298

    Insert

    Lamp1 (Lamp1 Rat)
    

    Tags

    Flag

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    May 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pCI pHluorin Syt3

    Plasmid

    #184504

    Purpose

    Mammalian expression of Synaptotagmin 3 with pH-sensitive fluorescent protein

    Depositor

    Edwin Chapman

    Article

    Dean et al Mol Biol Cell. 2012 May;23(9):1715-27. d

    Insert

    Synaptotagmin 3 (Syt3 Rat)
    

    Tags

    Super Ecliptic pHluorin

    Expression

    Mammalian

    Available Since

    May 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pGL3-MTS-ND1-W86-L14-G1333C-UGI-Puro

    Plasmid

    #198850

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND1) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ND1-W86-L14 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pGL3-MTS-ND5-W68-L15-G1333C-UGI-Puro

    Plasmid

    #198858

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND5) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ND5-W68-L15 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGL3-MTS-COX3-W16-L17-G1333C-UGI-Puro

    Plasmid

    #198846

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(COX3) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    COX3-W16-L17 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pGL3-MTS-ATP8-W9-L17-G1333C-UGI-Puro

    Plasmid

    #198840

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ATP8) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ATP8-W9-L17 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pGL3-MTS-ND3-Q26-L18-G1397C-UGI-Puro

    Plasmid

    #198854

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND3) by swapping Gln codon CAA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ND3-Q26-L18 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pGL3-MTS-ATP6-W68-L16-G1333C-UGI-Puro

    Plasmid

    #198838

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ATP6) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ATP6-W68-L16 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pGL3-MTS-ND4-W24-L18-G1333C-UGI-Puro

    Plasmid

    #198856

    Purpose

    Employ DdCBE-mediated mtDNA editing to ablate mtProtein(ND4) by swapping Trp codon TGA with stop codon TAA in C6 cells

    Depositor

    Bin Shen

    Article

    Tan et al Sci Adv. 2023 Apr 14;9(15):eadf2695. doi

    Insert

    ND4-W24-L18 TALEN
    

    Expression

    Mammalian

    Available Since

    May 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge