Hot Plasmids - May 2022
Type
Blog Post
...one visual barcode per cell and up to 200-plex with two barcodes per cell. The researchers validated their...visual barcodes for clonal multiplexing of cells in live imaging application. Each visual barcode consists...visual barcodes in use in A375 cell line. Image from Kaufman, et al, 2022.
This new barcoding technology... error rate for long sequence knock-ins
Visual barcodes for live cell clonal multiplexing
Improving ...interaction). The modularity of the system provides researchers better flexibility and makes the approach more...generate “single-use” transgenic lines. Instead, researchers can generate and maintain transgenic lines that...error rate. For a one kilobase insertion, the researchers reported an editing error rate of less than 0.3%...