We narrowed to 1,082 results for: TOR

... top Empty Prime Editing gRNA Vectors A selection of empty gRNA vectors suitable for prime editing are...tevopreq1-GG-acceptor Mammalian hU6 epegRNA BsaI No mRFP1 David Liu 174039 pU6-tmpknot-GG-acceptor Mammalian...Find prime editor plasmids for (search and replace) genome editing. CRISPR...enzyme is named PE1 . PE1 and most other prime editors use the Moloney murine leukemia virus (M-MLV) reverse...can be used in PE2–PE5 systems PE6 — small prime editors with optimized RT and/or Cas9 domains PE7 — addition...addition of RNA-binding exonuclease protection factor La to PEmax to enhance pegRNA stability epegRNA —... table below. Use the search bar to find a gRNA vector based on expression system, promoter, the type ...

... Viral Vector Packaging Service AAV Chemogenetics Viral Vector Packaging Service: Chemogenetics...information about this field. Receptor Activating hM3D(Gq) DREADD rM3D(Gs) DREADD Inhibitory HCAD(Gi) DREADD hM4D...Promoter Synapsin CaMKIIa CD68 Dlx GFAP nEF CAG E2 regulatory element Tag Fusion tags mCherry HA Non-fusion...AAV9 Retrograde AAV PHPeB Clear Filters ID Name Receptor and Activity Reporter/Tag Cre requirement Serotype...pAAV-hSyn-dF-HA-KORD-IRES-mCitrine kappa-opioid receptor (KOR) - Inhibition IRES mCitrine Cre-dependent...Karpova and Schaffer labs. See the Retrograde AAV Inventory Page . Browse all Chemogenetics AAV Don’t See ... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...

... Depositor Collections Allen Institute for Brain Science ...Enhancer AAV plasmids are plasmids which use genomic regulatory sequences — termed enhancers — to drive cell ... AAV delivery. The collection includes the top vectors with the highest specificity and brightness, assessed...pAAV-AiE2563m-minBG-SYFP2-WPRE3-BGHpA AiP1969 AiE2563m SYFP2 Entorhinal area - L2 pyramidal neurons Hippocampal formation...pAAV-AiE2403m-minBG-SYFP2-WPRE3-BGHpA AiP1772 AiE2403m SYFP2 Entorhinal area - L2 pyramidal neurons Hippocampal formation...pAAV-AiE2664m-minBG-SYFP2-WPRE3-BGHpA AiP2107 AiE2664m SYFP2 Entorhinal area - L3 pyramidal neurons Hippocampal formation...pAAV-AiE2664m-minBG-iCre(R297T)-BGHpA AiP20169 AiE2664m Cre Entorhinal area - L3 pyramidal neurons Hippocampal formation...

...interest. Browse Cancer Research Plasmids by Pathway mTOR mTOR is a protein kinase that anchors a signaling network...Cancer Research Broad Target Accelerator Plasmids: Collection of vectors from the Boehm , Hahn , Meyerson...mutated gene in human cancer, is a transcription factor and tumor suppressor. Wnt Coming soon! Kits and...mutant alleles described in the initial Target Accelerator publications, focused on somatic variants found...pan-cancer” analyses. Cancer Pathways ORFs Kit : Set of vectors from the Sabatini & Wood Labs containing cDNAs ... Lab RAS Pathway Clone Collection 2.0 : Set of vectors from the Esposito Lab for use with the Gateway®...permit construction of RAS pathway gene expression vectors for in vitro and in vivo research. TP53 Mutagenesis...

...basic-hFX-promotor(1kb) FXN hFXN Friedreich ataxia Michael Ristow 14979 pGL3-basic-hFX-promotor(1,3kb) FXN...basic-hFX-promotor(2,5kb) FXN hFXN Friedreich ataxia Michael Ristow 14981 pGL3-basic-hFX-promotor(2kb, distal...TARDBP His, GST, Factor Xa cspA ALS Aaron Gitler 27452 pCold TDP43 G294A TARDBP His, Factor Xa cspA ALS Aaron...M337V TARDBP His, Factor Xa cspA ALS Aaron Gitler 27454 pCold TDP43 Q331K TARDBP His, Factor Xa cspA ALS Aaron... DCTN1 CMV ALS, motor neuron disease Trina Schroer 51221 CMV-CC2 DCTN1 CMV ALS, motor neuron disease Trina... ALS, motor neuron disease Caren Norden 105971 pME mKate2-dynactin1-811 DCTN1 mKate2 ALS, motor neuron...237005 VCP-HaloTag Vector VCP Halo CMV ALS Promega Corporation 237006 HaloTag-VCP Vector VCP Halo CMV ALS...

... Viral Vector Packaging Service AAV Serotype Testing AAV Viral Vector Packaging Service: ...available from Addgene's viral service. Control EGFP vectors in various serotypes for serotype testing: AAV1...addition to the standard 100 µL sample size, the vectors listed below are also available as 20 µL. The ...experiments. For more information, see our full AAV inventory or our AAV production page . Note: For a list ...100 µL sized sample, please see our Control AAV Inventory . The catalog ID for the 20 µL sized testing sample...does not have the suffix (for example, AAV1). AAV Vectors for Serotype Testing pAAV-CAG-GFP (Plasmid #37825... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...

...cellular receptors. The cellular receptor for SARS-CoV-2 and SARS-CoV is the angiotensin receptor, Angiotensin...Additional Addgene resources ACE2 plasmids - Host cell receptor mediating the entry of SARS-CoV and SARS-CoV-2...Cytokines - SARS-CoV-2 infection induces a cytokine storm response in the body. For a full list of cytokines...) Ectodomain and RBD mutants. SARS-CoV-2 Spike Receptor Binding Domain Deep Mutation Scanning Library ...mutations for comprehensive mapping. SARS-CoV-2 Spike Receptor Binding Domain Site-Saturation Mutagenesis Libraries...Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream...TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein . Journal ...

...viral vectory packaging service. Browse constructs currently available in viral format.... Viral Vector Packaging...Browse In-Stock AAV Adeno-associated virus (AAV) vectors are safe and useful gene delivery tools that effectively... in small volumes, and ready to ship. All viral vector preps are purified by density centrifugation. Addgene...service. You can choose a transfer plasmid from our repository and request packaging in one of eight serotypes...or AAVrg). For more information, visit our Viral Vector Packaging Service overview. Function Chemogenetics...Monster, Brainbow Molecular Tools Tetracycline Transactivators, Affinity Purification, Cell Ablation, CRISPR...

...Surface Display cDNA Depositor Collections A modular set of plasmids from a depositor organized by a common...Collections Addgene Plasmid Collections Addgene's repository contains 172,416 plasmids . We've gathered our...our curated plasmid resources, kits, and depositor collections on one page to help you find what you're...looking for a non-plasmid item, browse our entire repository . Plasmid Resources Our curated resources group...common use. Click here to view all collections. Depositor Collection Types CRISPR Fluorescent Proteins Protein... Protein Expression Synthetic Biology Viral Vectors Communities Find a scientific community that has established...Variation on Function (IGVF) Consortium Krüppel-like factors (KLF) Plasmid Resource RESOLUTE Plasmid Collection...

... Viral Vector Packaging Service AAV Controls Viral Vector Packaging Service: Control...quality AAV preps from select plasmids in the repository. Browse our control AAV collection, including...Karl Deisseroth 135630 pAAV-S5E2-dTom-nlsdTom E2 regulatory dTomato Constitutive 1, 9, PHP.eB Jordane Dimidschstein...Dimidschstein 135631 pAAV-S5E2-GFP-fGFP E2 regulatory EGFP Constitutive 1, 9 Jordane Dimidschstein 135641...135641 pAAV-S5E6-dTom-nlsdTom E2 regulatory dTomato Constitutive 1 Jordane Dimidschstein 137135 pAAV-Ef1a-oScarlet...Karpova and Schaffer labs. See the Retrograde AAV Inventory Page . Don’t See What You’re Looking For? Our ... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...

... Viral Vector Packaging Service AAV Monosynaptic Neuronal Tracing Viral Vector Packaging Service... Addgene does not distribute rabies virus. AAV Vectors for Monosynaptic Neuronal Tracing ID Name Description...specifically into cells that express the TVA viral receptor. Thus, by pseudotyping the rabies virus with EnvA...specifically targets the starter cell via the EnvA receptor. RABV is able to replicate in the starter cell...free to infect neighboring cells via G-protein receptors, which are naturally expressed at presynaptic ... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...format. Please note this does not guarantee viral vector packaging service, but lets us know what viruses...

...luciferase reporter vectors for sensitive gene expression analysis and fusion vectors containing tags such...luciferase reporter vectors for sensitive gene expression analysis and protein fusion vectors for detecting ... Depositor Collections Promega Plasmid Collection Promega...sensitivity. These assays are ideal for real-time monitoring of signaling pathways, investigating RNA regulation... without disturbing the virus of interest and monitoring endogenous protein dynamics in highly scalable...with the NanoBRET 618 fluorophore, as the energy acceptor. Live-cell reagents allow you to detect PPI induction...

...fluorophores, excitatory and inhibitory opsins , genetically-encoded calcium indicators, and rabies targeting... Depositor Collections INTRSECT Plasmid Collection INTRSECT...INTRSECT (intronic recombinase sites enabling combinatorial targeting) is a synthetic molecular targeting...Flp AND NOT Cre Yes Dual recombinase-dependent: Excitatory Opsins Addgene ID Plasmid Logic Sites and Mutations...Flp AND NOT Cre Yes Dual recombinase-dependent: Inhibitory Opsins Addgene ID Plasmid Logic Sites and Mutations...Deisseroth K. 2014. Targeting cells with single vectors using multiple-feature Boolean logic. Nat Methods...Krook-Magnuson E. 2019. A novel population of long-range inhibitory neurons. Preprint (Link opens in a new window...

... Viral Vector Packaging Service AAV Optogenetics Viral Vector Packaging Service: Optogenetics...quality AAV preps from select plasmids in the repository. Browse our optogenetics AAV collection, including...plasmids available in Addgene's collection. Opsin Excitatory Wild-type ChR2 ChR2/H134R soCoChR ChR2/other ... Chrimson, ChRmine, ChroME, ChETA, C1V1 (t/t) Inhibitory Arch and variants eNpHR and variants InSynC (...Bidirectional BiPOLES Promoter CAG CaMKII CBA Dlx E2 regulatory element EF1a/nEF GFAP Synapsin TRE Fluorophore...Karpova and Schaffer labs. See the Retrograde AAV Inventory Page . Don’t See What You’re Looking For? Our ... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...

...Resources SGC: www.thesgc.org SGC Toronto: www.thesgc.org/scientists/groups/toronto Protein Database (PDB): www.pdb.org...without restriction. Many SGC plasmids from the Toronto, Oxford and Stockholm sites have been deposited...the SGC Plasmid Collection By All Plasmids SGC Toronto SGC Oxford SGC Stockholm Bacterial Expression Plasmids...Thrombin cleavage, Bac-to-Bac Baculovirus Expresion vector 26117 pNIC-CH EF199843 Hexahistidine tag, AmpR ...cleavage, AmpR 26095 pFHMSP-LIC-N N/A Expression vector for secreted proteins with N-terminal hexahistidine... System, AmpR 26100 pFHMSP-LIC-C N/A Expression vector for secreted proteins with C-terminal hexahistidine...

...shRNAs are often delivered using viral vectors. Lentiviral vectors are a preferred method for long-term ...Plasmid Vector Type PI Publication Additional Resources Addgene Resources pLKO.1 cloning vector protocol...long-term gene silencing. Once the viral vector is taken up by a host, the viral genome is transcribed, producing.... shRNA Plasmids Browse our selection of empty vectors for cloning in shRNAs. Most plasmids are in a lentiviral...Lentiviral packaging plasmids Web Resources Trono Lab Lentivectors Toolbox Optimized shRNA design in pSico with...

...Empty gRNA Vectors Select an empty vector for your experiment based on a variety of factors. Browse Plasmids...for you to download. CRISPR Resources : Browse depositor protocols, find software for gRNA design and deep...discover links to CRISPR forums, and more. CRISPR History : Learn how CRISPR was modified from a bacterial...information into a specific DNA site. Base Edit Base editors precisely edit DNA without promoting DSB formation...Transcriptional Regulation Activate dCas9 fused to an activator peptide activates gene expression. Interfere dCas9...

...permissive cells that express ACE2, the cellular receptor for SARS-CoV-2, in a single round of viral entry...NL4-3 mCherry Luciferase Lentiviral dual reporter vector expressing mCherry and firefly luciferase to simultaneously...105621 Lenti-luciferase-P2A-Neo Lentiviral reporter vector expressing firefly luciferase with neomycin resistance...pLentiEGFPdestablized - EFS-EGFPd2PEST-2A-MCS-Hygro Lentiviral vector expressing destabilized EGFP. Neville Sanjana 164432...pHAGE-CMV-Luc2-IRES-ZsGreen-W Lentiviral dual reporter vector expressing firefly luciferase and ZsGreen. Alejandro...David Nemazee 161030 Zhou-pLOV-GFP-Luc Lentiviral vector expressing GFP and luciferase for use as a reporter...coronaviruses (DOCX, 184 KB) Addgene Blog Posts Viral Vectors 101: Pseudotyping Antibody Neutralization Response...

...signed by an authorized signatory at the recipient institution. An authorized signatory is someone who can ...also adding additional filters such as expression, vector type, species, and more. Plasmids Browse the table...Golden Gate Assembly Standards Kit Cloning Eric Cantor Kit for using comprehensive end-joining ligation...Genome Editing Jim Haseloff 79 parts plasmids and vectors for genome engineering in the plant model Marchantia...Libraries CRISPR Thorsten Stiewe Use these donor vector libraries for CRISPR/Cas9-mediated saturation genome...entity is qualified to receive materials from our repository. All purchases are subject to Addgene's Terms...

...mEGFP AICSDP-60 mEGFP Transcription factor SOX-2 Transcription Factor 124607 ACTN2-mEGFP AICSDP-63 mEGFP...repeat-binding factor 2 (TRF2) Telomeres 168799 CTCF-mEGFP AICSDP-144 mEGFP CCCTC-binding factor (CTCF) CTCF-binding... Depositor Collections Allen Institute for Cell Science Plasmid...UBTF-HaloTag AICSDP-80 HaloTag Nucleolar transcription factor UBF Nucleolus (fibrillar center) 133964 SON-mEGFP...TFAM-mEGFP AICSDP-72 mEGFP Mitochondrial transcription factor A (TFAM) Mitochondrial nucleoids 164499 EZH2-mEGFP...