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We narrowed to 581 results for: arl

Showing: 181 - 200 of 581 results

  1. Adenovirus Guide

    Type
    Guide
    ... divided into early (E1A, E1B, E2, E3, E4) and late (L1, L2, L3, L4, L5) regions. Early transcripts are...5 (Ad5) and have been produced by replacing the early and late adenoviral transcript regions between the...rAdV vectors, as well as the deletion of the other early gene regions, E2 and E4. These modifications aimed... when administered in vivo, however deletion of early genes also resulted in a reduction of viral vector...Adenoviral plasmid E2A, E2B, E3, E4 in trans Adenoviral early transcript regions involved in viral DNA replication...

  2. New Viral Vectors - Spring 2025

    Type
    Blog Post
    ...Jordane Dimidschstein New serotype pAAV_hSyn-PdCO-mScarlet-WPRE AAV1 Optogenetics Ofer Yizhar New viral ...pAAV-Ef1a-fDIO hChR2(H134R)-EYFP AAVrg Optogenetics Karl Deisseroth New viral tool AiP13987: pAAV-AiE0452h...

  3. New Viral Vectors - Summer 2024

    Type
    Blog Post
    ...service with multiple serotypes pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE AAV1, AAV5 Optogenetics Yizhar New...with multiple serotypes pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE AAV1, AAV5 Optogenetics Yizhar New viral ...

  4. Performing In Vivo CRISPR Screens Using the FITS Approach

    Type
    Blog Post
    ...., 2024), developed and deposited at Addgene by Arlene Sharpe’s lab, enables in vivo screens in naïve ...here! Marty LaFleur is a Postdoctoral Fellow in Arlene Sharpe’s laboratory at Harvard Medical School and...

  5. Newly Updated AAV Data Hub!

    Type
    Blog Post
    ...more. A great submission includes: Images that clearly show viral spread and cellular tropism* (min. 300...serotype An abstract that summarizes your experiment clearly and concisely* *required for a DOI. Reports that...

  6. Interview with Bart Newland, Addgene’s Newest Board Member

    Type
    Blog Post
    ...Newland. Newland is General Counsel at Atalanta, an early-stage biotech company that is developing RNAi therapeutics...up going straight to law school. This was in the early 80s, and biotech was really just taking off. I found...

  7. Science Communication for Everyone

    Type
    Blog Post
    ... of Toronto. The Addictive Brain was founded in early 2018 with the goal of communicating science to non-scientists... eLife ambassador, SfN community leader, and an early research career panelist at BioTechniques.     Additional...

  8. Addgene's Top Blog Posts from 2020

    Type
    Blog Post
    ...Scientists by Jennifer Tsang These tips were written early on in the pandemic. Later in the year, Joanne Kamens...methods for extracting DNA without a kit too. 1. Early Career Researcher Toolbox: Free Online Molecular...

  9. Our Most Popular Blog Posts from 2019

    Type
    Blog Post
    ...mouse, fruit fly, yeast, zebrafish, and worm. 4. Early Career Researcher Toolbox: Free Tools for Making...from the community. Are there any topics you particularly like or maybe something you’d like to see more...

  11. X-CHIME: Context Dependent Germline Knockout in Immune Cells

    Type
    Blog Post
    ... systems, developed and deposited at Addgene by Arlene Sharpe’s lab, allow for wide deployment of in vivo...here!   Marty LaFleur is a Postdoctoral Fellow in Arlene Sharpe’s laboratory at Harvard Medical School and...

  15. New Norepinephrine Indicators: nLightG and nLightR

    Type
    Blog Post
    ...alpha-1a adrenergic receptor; nLightG contains circularly permuted green fluorescent protein (GFP), and...green fluorescent proteins. nLightR did perform similarly to GRABNE, and having both colors allows for increased...

  16. In Living Color: The Skinny on In Vivo Imaging Tools

    Type
    Blog Post
    ... spectral region in which mammalian tissues are nearly transparent. As Verkhusha explained it to me, the...tissues 20-fold greater than any fluorescent protein earlier described. “Until our proteins, there were lots...

  17. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    ...popular bacterial genome engineering tools, with early reports of 40%–60% efficient integration (Klompe... al., 2019). Type I-F CASTs were found to be particularly useful. But they were barely effective at editing...

  18. Year of the Camelid: Antibody Style

    Type
    Blog Post
    ... to manipulate cellular functions, like in this early example we highlighted back in 2015, where sdAbs...  So where do all these sdAbs come from? In the early years of sdAbs development, the process started ...

  19. Cellosaurus: A Cell Line Information Database

    Type
    Blog Post
    ...new resources with the scientific community – particularly ones that help address ongoing problems, like...growing cell line information database describing nearly 145,000 cell lines. Cellosaurus Cellosaurus seeks...

  20. Fostering communication in remote collaborations

    Type
    Blog Post
    ...experiments. Therefore, it’s crucial that everyone meets early on to set expectations for the output that will ... which parts of the project, and, as mentioned earlier, how frequently the entire group will meet. You...
Showing: 181 - 200 of 581 results