We narrowed to 568 results for: VIT

...allow researchers to independently control the activity of two populations of neurons at once. Addgene...is a toolset that lets you turn the electrical activity of neurons on or off using pulses of light. By...both activators as well as silencers of neural activity. Since then, there has been a steady stream of...

...genome editing tool. However, Cas9’s endonuclease activity can be limited by the need for a specific PAM ...are ion channels that can be used to silence the activity of neurons. Earlier this year, the Hegemann lab...valuable optogenetics feature when studying neuronal activity. The researchers identified MerMAIDS from their...

... Chiasson is currently using VAMP-seq to study vitamin K epoxide reductase (VKOR) variants. VKOR is an...assays for measuring human serotonin transporter activity. Unger also plans to use the serotonin receptor...genotype the patient and rapidly test the variants in vitro against different drugs and dosages.  Michal Bernach...

...transduction profiles in different AAV serotypes both in vitro and in vivo when compared to the conventional AAVs...et al., 2017), exo-AAV2 in mouse retina after intravitreal injection to transduce bipolar cells and photoreceptors...robust gene delivery into the murine retina upon intravitreal injection." Scientific reports 7 (2017): 45329...

...we are missing is the unmeasurable skills and productivity coming from that casual discussion on the way...this is an underrated ritual that really drives creativity and novelty in scientific research and in any...springboard for future discussion. Collaboration and creativity are pivotal in writing publications/grants too...

...relationship with authenticity and not discomfort: Invite the new contact to connect on LinkedIn and always...make the relationship stronger.  If appropriate, invite them to speak for your organization, mentoring ... simple question so I accepted the connection invitation. They now message me frequently and ask me how...

... on bacterial expression systems here) and the activity of the plant compounds on these proteins will ... be tested. Investigating changes in neuronal activity after ischemic brain injury Dr. Gohar Tsakanova...image cortical neurons and study changes in neural activity after ischemic brain injury. Additionally, optogenetic...

...free to anneal to complementary ssDNA molecules in vitro. Figure 1: Cas9 binding to the cleaved DNA... if we could leverage this model (built from in vitro studies) to boost the efficiency of sequence replacement...enables sequence replacement without cutting Our in vitro results also demonstrated that catalytically inactive...

...from the 3’ end, while its native endonuclease activity degrades the displaced strand.   Figure... the nick site, which was expected since the processivity window of PolI is 15-20 bp. EvolvR’s on-target...bacteriophage T7 DNA polymerase increased the processivity of PolI3M, and thereby increasing the editing...

...from AAV2 because they demonstrate high promoter activity (Earley et al. 2020), but non-AAV2 ITRs can be...within Inverted Terminal Repeats (ITRs) on the Productivity, Genome Packaging, and Potency of AAV Vectors...regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression. Sci Rep,...

...encoded calcium indicators (GECIs) have become a vital tool in neuroscience research. These fluorescent... calcium levels change rapidly during neuronal activity, scientists can use GECIs to watch neurons fire...fluorescent calcium ion indicator for imaging neural activity. bioRxiv 2025.07.28.667269; doi: https://doi.org...

...upon binding of CNO thus showing no constitutive activity. There are an array of DREADDs that activate different...neuroglia, and have different effects on neuron activity (firing or inhibition). AAV preps from DREADD ...chemogenetics and a concise table of DREADDS and their activity in neurons on Addgene’s chemogenetics guide.   ...

...ability to post a preprint as evidence of their productivity that can be shared with hiring and review committees...encourage and consider preprints as demonstration of productivity. Part of an open scientific communication ecosystem...details that you couldn’t fit on your poster, or invite attendees to read and comment online! Want the ...

...the insert. Gateway® technology (developed by InvitrogenTM) is essentially a more modern version of this...CcdB-resistant strain is ccdB Survival™ from InvitrogenTM. Using either DB3.1 or ccdB SurvivalTM, one ...a variety of useful resources and protocols! We invite feedback from all members of the research community...

... you to share and build support for your ideas, invite others into decision making processes, and even...usually) presenting either to share knowledge or to invite critique onto an ongoing project. So whenever you...Conflict Resolution Transferable Skills Guide: Creativity...

...in cells, and without something to block RNase activity upon cell lysis, RNA is degraded. To effectively...-based solutions that work by inhibiting RNase activity within cells or tissues- they don’t actually chemically...A (1974) The effect of ammonium sulfate on the activity of ribonuclease A. Biochimica et Biophysica Acta...

...sensors for a diverse set of fat-soluble hormones, vitamins, and dietary lipids. Included in this family are...progesterone, androgens, and estrogens), fat-soluble vitamins A and D, thyroid hormone, fatty acids, oxysterols...transfection platform for assaying transcriptional activity, for example, was a key development in the functional...

...personal identity. We do this through a variety of activities, including creating educational materials and...addition to events that we put on, we are often invited to present our materials or speak about our experiences...our science communication posts Extracurricular activities for a strong science career path Resources on...

...characterized by deficient phosphomannomutase (PMM) activity due to mutations in the PMM2 gene. Videira’s group... Decades ago, other labs discovered that the in vitro functions of 11 different Arg-mutant enzymes could...phenotypes. Developing a rapid test for the functional activity of VUSs will enable more accurate diagnosis of...

...interact.  When this interaction occurs, BirA* activity is restored, and nearby proteins are labeled with...BirA* enzyme. When this interaction occurs, BirA* activity is restored, and nearby proteins are labeled with...proteins Y and Z part ways, BirA* biotinylation activity ceases. After biotin tagging of proteins in both...