We narrowed to 581 results for: arl
-
TypeBlog Post... to manipulate cellular functions, like in this early example we highlighted back in 2015, where sdAbs... So where do all these sdAbs come from? In the early years of sdAbs development, the process started ...
-
Tips for Improving Your Next Manuscript
TypeBlog Post...consisted of graduate students, post-grads, and early career scientists. Over the course of the class,...welcoming us. Then it was time to work! Set up similarly to the online class, we met as a group for sessions... -
Running for Rare Disease, Running for FOP, Running for AJ
TypeBlog Post... in Cambridge, MA. When I joined Sanofi/Genzyme nearly three years ago I decided it was time to get in...analytical development. His areas of expertise include early stage drug discovery and pre-clinical development... -
Addgene at the ASM Microbe 2016 Conference
TypeBlog Post...Labeling Plasmids from the Barbier lab). Bright and early on Saturday morning, John Doench’s opening presentation... to the scientific community. However, from the nearly 4000 posters presented at the conference, it looks... -
Walking beside Academia and giving it a high five: My transition from graduate work to a position at Addgene
TypeBlog Post...have been unwise of me to join Addgene. This is particularly true in my position as an Outreach Scientist...pretty hefty bumps during my graduate training. I particularly think that too many young scientists are led... -
Addgene @ Keystone: Thoughts on Precision Genome Engineering and Synbio
TypeBlog Post...reagents so freely with the academic community has clearly made a huge impact on this field. Advances in ...answering biology customer service questions for nearly 7 years, and my colleagues and I have an internal... -
10 Ways to Share Your Science!
TypeBlog Post...some science on the one you already have. Read my earlier post about Scientists on Twitter here. 4) If ...commitment, start your own blog. Plan to write regularly and, when you are ready, tell your friends or ... -
What the HEK?
TypeBlog Post...two areas of research where HEK cells may be particularly useful due to their intrinsic properties. ...by mycoplasma and bacteria, but HEKs are also particularly vulnerable to viral infection. Yes, your cells... -
Single-cell tracking of lineage and identity with CellTag
TypeBlog Post...time point, making it difficult to investigate how early expression patterns influence reprogramming outcomes...However, distinct transcriptional states were seen as early as day 6. All together these results suggest that... -
New and Upcoming Viral Vectors - December 2019
TypeBlog Post...We have also packaged hChR2(H134R) plasmids from Karl Deisseroth’s lab, which includes pAAV-hSyn Con/Fon...WPRE-SV40 124650 AAV9 pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 55645 AAV5 pAAV-hSyn Con/Fon hChR2(H134R... -
Antibody Neutralization Response Against Pseudoviruses Expressing SARS-CoV-2 Spike Protein Variants
TypeBlog Post...Alpha variant), B1.1.298, and B.1.429 (Epsilon), nearly as well as they could for the wild-type. However...TM, Clayton KL, Nitido AD, Murali MR, Alter G, Charles RC, Dighe A, Branda JA, Lennerz JK, Lingwood D,... -
Safe Port in a Storm...How Addgene is Weathering the Pandemic
TypeBlog Post...expected to be in this here and now. Our closure was earlier than most companies. Since the start of this crisis... to make most of our payroll for the spring and early summer months. We are also extremely grateful to... -
In Vivo Biotinylation of Bacterial Fusion Proteins
TypeBlog Post...plasmid in NEB T7 SHuffle bacteria (C3029J). We are clearly NEB “fanboys” as the bacteria significantly enhance...biochemist in the Vanderbilt Eye Institute and is particularly interested in cell signaling. Additional... -
Identifying Sequence Elements with SnapGene's Feature Database
TypeBlog Post...commercial plasmids were inconsistent and sometimes clearly wrong. In an effort to be rigorous, we dug into...Biology at the University of Chicago. He was an early depositor at Addgene, and conceived SnapGene because... -
What Do I Do Now? Academic v. Non-Academic Career Decisions
TypeBlog Post...better, no grant writing Job changes can happen regularly (every 4-6 years is common), but this can also...diverse options and how to take advantage of them early is one way to smooth your path to a fulfilling career... -
Donations from Addgene to Yield Answers for Rare Disease Researchers
TypeBlog Post...by mutations in the OCRL1 gene that leads to the early death of young patients as their kidneys fail. The...interested in XP out of a desire to understand the early events in the transformation of healthy cells into... -
Crowdfight, a Platform to Boost Scientific Collaboration During COVID-19 and Beyond
TypeBlog Post... neutralize the SARS-CoV-2 virus. But while the early results were promising, the researchers did not ... the preprint repository BioRxiv. This example clearly illustrates the power of collaboration, which despite... -
Plasmids 101: Gram Negative and Positive Bacteria
TypeBlog Post...decolorized as gram negative. A German scientist, Carl Weigert, later expanded on Gram’s discovery, adding...resources. Bruckner, M. Gram Staining. https://serc.carleton.edu/microbelife/research_methods/microscopy/gramstain.html... -
Using CRISPR/Cas9 to Edit Disease Out of the Genome
TypeBlog Post...They are targeting the genes responsible for both early onset and late onset AD. In this study, the group...autosomal-dominant mutations that have been connected to the early onset of Alzheimer’s disease, as well as those that... -
Celebrate National Book Month with Addgene
TypeBlog Post...insects, mammals, and plants, among others. I particularly enjoyed the emphasis that microbes are neither...last 8 years. Since then, we’ve read books across nearly every genre you can imagine: gothic, mystery, sci-fi...