We narrowed to 591 results for: ARL
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TypeBlog Post...thinking: I wish I had this kind of experience earlier! After all, students build circuits in physics... about operating the rest of the car as well. Similarly, cell free expression systems contain all the ...
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Crowdfight, a Platform to Boost Scientific Collaboration During COVID-19 and Beyond
TypeBlog Post... neutralize the SARS-CoV-2 virus. But while the early results were promising, the researchers did not ... the preprint repository BioRxiv. This example clearly illustrates the power of collaboration, which despite... -
Celebrate National Book Month with Addgene
TypeBlog Post...insects, mammals, and plants, among others. I particularly enjoyed the emphasis that microbes are neither...last 8 years. Since then, we’ve read books across nearly every genre you can imagine: gothic, mystery, sci-fi... -
Fluorescent Protein Travel Awards - Protein Variants, a Serotonin Sensor, and an Artificial Leaf Replica System
TypeBlog Post... 2017. These travel awards are intended to help early career scientists attend a conference of their choice...evidence suggests that it is incredibly important for nearly every aspect of life.” Unger began with the a bacterial... -
Plasmids 101: Gram Negative and Positive Bacteria
TypeBlog Post...decolorized as gram negative. A German scientist, Carl Weigert, later expanded on Gram’s discovery, adding...resources. Bruckner, M. Gram Staining. https://serc.carleton.edu/microbelife/research_methods/microscopy/gramstain.html... -
Using CRISPR/Cas9 to Edit Disease Out of the Genome
TypeBlog Post...They are targeting the genes responsible for both early onset and late onset AD. In this study, the group...autosomal-dominant mutations that have been connected to the early onset of Alzheimer’s disease, as well as those that... -
Addgene Welcomes John Doench to the Advisory Board
TypeBlog Post...specificity in the miRNA regulatory process. This early research is still relevant to his work at the Broad...screens to learn more about cancer biology in Ed Harlow’s group at Harvard Medical School and then applied... -
Quick Guide to Working with Drosophila Part 3: Genome Engineering in Flies
TypeBlog Post...research (3). The sky is the limit. As mentioned earlier, even genes not found in Drosophila can be studied...immunology PhD at Harvard University. He has had nearly a decade of experience working with Drosophila ... -
Antibodies 101: Isotypes
TypeBlog Post... in Health and Disease. 5th edition. New York: Garland Science; 2001. Structural variation in immunoglobulin... in Health and Disease. 5th edition. New York: Garland Science; 2001. The distribution and functions of... -
Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME
TypeBlog Post...miRNA reporter podcast segment Discovered in the early 1990’s, microRNAs (miRNAs) are recognized as important...analysis of immune cells has been a gap in the field. Arlene Sharpe’s group at the Harvard Medical School developed... -
Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
TypeBlog Post...Therapies: CRISPR, Stem Cells, and Beyond meeting earlier this month. Another issue that arises for base...cannot be expressed until the base editor corrects early stop codons within T7 RNAP. A phage encoding the... -
Behind the scenes: Addgene’s new search engine and more
TypeBlog Post...results. The footer and improved menus we launched earlier in the year, as well as our redesigned homepage...categorization of our information in order to more granularly customize the search engine, and a scoping mechanism... -
Plasmids 101: Inducible Promoters
TypeBlog Post...between cell types or organisms, promoters are similarly variable. Bacterial promoters only work in prokaryotic...related species from which they were derived. Similarly, the various eukaryotic cell types (mammalian,... -
How to Keep a Lab Notebook for Bioinformatic Analyses
TypeBlog Post...inspired you to perform this analysis. Having a clearly stated, specific goal for each analysis will help...student at University of Pennsylvania. She is particularly interested in science communication and epigenetics... -
Advice for Starting a Biotech Company from a Grad Student turned Entrepreneur
TypeBlog Post...best, wins. He explained that entrepreneurs must clearly communicate their idea at various levels of complexity...works. “We use functional spectrometers from the early 1990s that were free and free to repair.” If the... -
Form Your Own Peer Mentoring Group: A How-To Guide for Scientists
TypeBlog Post...ends, some 50% of these groups continue to meet regularly, providing ongoing support, advice and accountability...most hits. Commit to a meeting schedule and meet regularly no matter what, even if one person can’t make ... -
Addgene: The First Twenty Years
TypeBlog Post...School. We want to give a special thanks to the early-adopter scientists, who trusted Addgene before we...— 10,000 plasmids deposited and available — and nearly seven before we had 1,000 depositing scientists... -
Viral Vectors 101: An Introduction to AAV
TypeBlog Post... also be used to ensure specificity; this is particularly helpful when wanting to target specific neuron...Dystrophy. InTech. doi: 10.5772/53023 Veldwijk, Marlon R., et al. "Development and optimization of a real-time... -
CRISPR 101: Cas9 vs. The Other Cas(s)
TypeBlog Post...Cas12a cleavage results in 5 bp overhangs and is particularly convenient for targeting experiments requiring...it targets RNA instead of DNA. This makes it particularly useful in generating transient edits of signaling... -
Choosing the B(right)est Fluorescent Protein: Photostability
TypeBlog Post...absorb the excitation light less efficiently. Similarly, decreasing the power of the excitation light ...experiments. As the photobleaching rate is not linearly related to power, the conclusions reached at high...