...has the sequence of the mutated gene the researcher is searching for), then the probe will bind to the sample...of DNA used saving the researcher both time and resources (3). Still, researchers generating transgenic...experiments allowed researchers to identify the location of genes. With this knowledge, researchers were able to...at the end as in standard PCR. This allows the researcher to compare different DNA sequences to see which...In the era before sequencing was commonplace, researchers used restriction mapping to investigate DNA sequence...running the products on an agarose gel allows a researcher to properly orient specific fragments of a DNA...This approach to studying DNA sequences helped researchers at a time when sequencing was still in the early...

...those by researchers hoping to increase community participation in new precision medicine research. A willingness...entails a lot of researching and writing – following the latest developments in genetics research, their applications...work in these fields of research, what often concerns them the most about research is its implications for...possibility of benefiting from the fruits of scientific research, and prevent technological advances from exacerbating...to dark episodes in the history of eugenics and research misconduct. Past ethical breaches such as the ...used to being very focused on narrowly-defined research questions in our field of interest. We often communicate...and awareness of issues outside of your field of research will allow you to better engage these diverse ...

...biomedical research: recommendations from the Future of Research Chicago Symposium F1000Research, 2016. Kyle...their careers (McDowell et al, F1000Research, 2014; Dolan, F100Research, 2016). These events have also...Shaping the Future of Research: a perspective from junior scientists."F1000Research 3 (2014). Pubmed PMID...Symposium and Workshop, organized by Future of Research, Academics for the Future of Science, and the ... More information can be found at http://futureofresearch.org/advocating-for-science-boston-2016/. Sign...Symposium Boston 2016 Changes since the Future of Research Symposia Ongoing challenges facing the scientific... 2014; Taylor, eLife, 2016). Several Future of Research (FoR) symposia held across the USA during this...

...required to study SARS-CoV-2, but with many academic research labs closed during the pandemic, it’s hard to ... are crucial for the advancement of SARS-CoV-2 research because they provide rapid access to validated... and much more have been critical for pandemic research. Image from Reproducibility for Everyone. Case...broad use and are now important for accelerating research into this virus. One such example is cell lines...repository for a variety of materials for life science research, including over 4,000 cell lines. Seventeen of...this study came from the Japanese Collection of Research Bioresources Cell Bank, part of the National Institutes...Nutrition in Japan. These results  will help researchers choose the best experimental model for further...

...reproducibility at some point. Usually it comes up when a researcher decides on a new project and begins by trying...variation in experimental conditions will derail a research program (think a subtle difference in mouse chow...sure you do what you can to help your fellow researchers advance science overall. Communication is the...inadequate information about what the original researchers actually did. Admittedly, the differences are...they come to light, it’s clear that what the researchers thought was a problem in fact was not, and it...in an accessible and consistent way so other researchers can use them, to making sure that methods and...to being open and willing to share with other researchers to help them troubleshoot and understand. All...

...Member and lead researcher at Imperial College London, Dr. Tom Ellis. Dr. Ellis does research in synthetic...chromosomes, and obstacles to becoming an academic researcher. Listen to the interview with Tom Ellis Podcast...breakdown Intro: How Tom ended up in academia and his research goals. From grad school to a startup and back ...in academia. Learning how to build a lab and a research program and difficulties with work-life balance... synthetic biology to the UK with foundational research, training, startups, and real applications of ..., disciplined, and open techniques. Chapter 4: Research projects underway in the Ellis lab including yeast...adoption of synthetic biology techniques in biology research as can already be seen with things like DNA synthesis...

...postdoctoral fellow at the Morgridge Institute for Research in Madison, Wisconsin. It is commonly cited that...perform in vitro kinase reactions. Often, however, researchers lack knowledge of the regulatory kinase, access... phosphoserine (as described below) provides researchers with a valuable tool for understanding the contribution...curious anomaly amongst a subset of methanogenic archea: these organisms lacked a classic cysteinyl tRNA... phosphoserine (Sep)-tRNA synthetase enabled researchers to create an orthogonal translation system (OTS...encoding the ORF to be expressed Finally, the researcher needs a plasmid encoding their open reading frame...non-phospho-incorporated proteins purified from the system, researchers can run samples on SDS-PAGE gels containing Phos-Tag...

...standardized process of good research practice: computer simulations, in vitro research, animal models, and several...actively being experimented on, too.) However, as research published on December 13 shows us, CRISPR/Cas9...additional public fora for data review, and more lab research could be used to bring scientists and the public...for proof that this model of public involvement, research, and consensus can happen. We just have to look...Wellcome Trust funded a center for mitochondrial research to investigate the scientific possibility, safety...mitochondrial disease;” The Nuffield Council began their research into both novel and previously established ethical...Nuffield Council emphasized, the key to moving research from bench to bedside is, in addition to thorough...

... awardees and their research. These researchers span four continents and research diverse topics including...scientific resources, equipment, and plasmids to researchers in resource-limited settings. More specifically...Labs plasmid grant provide plasmids to these researchers. In the third round of the Addgene-Seeding Labs...more about the five awardees and their promising research projects.   Understanding drug resistance mechanisms... tuberculosis care and control. In her current research, Sheen aims to identify new genes related to PZA-resistance...bacterial engineering using CRISPR on our blog). Her research should provide us with a better understanding ...field of bacterial and fungal pathogenesis. Her research focuses on a collection of pathogenic Klebsiella...

...perform research there temporarily. The length of stay could be from a month to a year. The researcher remains...visit   Design and communicate a research plan Your time at the new research site is limited, and we all know...collaborations and fresh perspectives. For trainee level researchers, it can expose them to a new institute and mentor...lab So, you’ve identified a gap or need in your research and decided you want to pursue a visiting position...your lab collaborates with that can fulfill your research needs, that is probably the easiest path. Some...programs are often great choices if they fit your research needs. What are your options if neither of these...just reach out to start the conversation. Many researchers are open to sharing knowledge and establishing...

...not just "research and publications” What are the skills you developed through your research? Don't simply... from the research itself, but from what was necessary in order for you to do your research. For example... your publications, academic performances, and research experiences, you now have merely two pages to ...simply write about the research you did. Emphasize the skills. If you studied astronomy or bioinformatics...on these skills. The only exception is when the research topic you have done is closely related to the ...are applying for, in which case talk about your research, as an understanding of the topic will give you...How about facilitating a collaboration between research groups? Perhaps you had some supervisory experience...

...Duedu, a researcher at the University of Health and Allied Sciences in Ghana. He’s done research at a number...distribute plasmids to researchers in developing regions and thereby accelerate their research. Kwabena came across...learning and doing research at Novartis. Listen to learn how Kwabena plans to use his research experiences as...molecular biology research programs. 30:57 - 40:16 : Kwabena's public health research, the HEAD outreach...work in Ghana - Building a bioresource to attract research funding. Using current resources to develop microbiology...about dietary health. 40:17 - 44:14 : Microbiome research - working with bacterial communities both on the...down and talk with us.  Kwabena Duedu, PhD is a researcher at the University of Health and Allied Sciences...

...immunological research. Here the Zhou group presented Opto-CRAC which allows a researcher to control immune...Research tackling questions in the fields of Cancer, Inflammation and Immunity, as well as various combinations... (so called “Immuno-Oncology”) is exploding. Researchers are increasingly able to harness the body’s immune...impression from this conference was that Cancer Researchers and Immunologists are coming together to tackle...Michael Karin from UCSD: “The problem with cancer research is that it is too fragmented and focused ... to...conference which reflect how cancer/immunology researchers are preparing and carrying out this multi-pronged...immunosurveillance have a look at our Immunology Research Plasmids and Resources. Studying the immune system...

...scientist, perhaps the most important part of your research is communicating the results of the work. Yes,...other: from formal mechanisms like publishing a research article, presenting a conference poster or talk...drafted. Preprints were one of the key routes for researchers to share information about the emerging SARS-... recognition for their efforts, inspire future research, and increase their impact. Open Access and Transparency...process among a few individuals.  Early-career researchers especially enjoy the ability to post a preprint...and other modes of scientific communication. Researchers often post a preprint at the same time as, or...communication needs. The most often-cited reasons researchers might not post a preprint are reluctance to share...

...doing your research in a group or facility that is a world leader in your chosen area of research (either... this already!” But, you do need to be able to research and write your application, then give it to someone...application is rushed (whether the idea isn’t properly researched / developed or the application is full of typos...important things reviewers will be looking for in your research proposal are originality and relevance. When reading...? This can sometimes be tricky, as most of our research builds on ideas and findings from our own or other...because it is the best place in the world for your research to rapidly progress. Need Help Building Your Scientific... asking for a 200-300 word explanation of your research for non-scientists. Most fellowships are funded...

... the search of phages for therapy Phage Directory started out as a directory of phage researchers and ... Zheng also saw the need to archive phage reagents. If a phage researcher retires, it's likely that the...whirlwind three days in November 2017. #Phage researchers! I am working with a team to get Burkholderia...be sent out to the directory earlier, but the researchers in the directory are volunteering their time ...information was very fragmented. A particular phage researcher may only know how to prepare phage for one application...another or they may have only used phage in basic research but not therapeutically: not all labs in Phage...the phages are lost if they are not archived. “It’s very sad because it’s years of work,” Sacher says....

...published data by biomedical researchers and ready access to stably archived large-scale datasets by computational... of interest using a simple keyword search. For example, searching the term "breast cancer" returns 40...screens and whether that data is useful for your research. Fortunately, there’s a growing open repository...than 45 publications, beginning with the seminal research articles that demonstrated the feasibility and...data files, BioGRID ORCS makes it possible for researchers to query all public CRISPR results for any gene...screen results available to the entire biomedical research community, but also allows cross-interrogation...its PubMed identifier, which can also be used to search the entire CRISPR database for particular screens...

...of the older cell lines in the research community, many cellular research tools have been optimized specifically...the cost of production. Research applications There are two areas of research where HEK cells may be particularly...utilized to transduce cell lines for basic science research all the way up to the production of clinical viral... candidate cell line model for cancer-specific research. Membrane receptors and ion channels are often...expression of native channels.  No matter what your research question, HEK-293 is known for reproducible results...seamless transition of biological tools to other researchers using the cell line. What the HEK is wrong with...culture. This can affect factors that could skew research results (gene expression, growth rates, etc.)....

...This post was contributed by Future of Research Executive Director, Gary McDowell. On Dec 1st, the threshold...How did this change in labor laws come about? In March 2014, the White House issued a memorandum to the...issued by the Department of Labor. At Future of Research, our volunteers have been helping to gather information... to the National Institutes of Health National Research Service Award (NRSA) stipend levels. In theory...workforce. Based on our communications with and research on these institutions, we can say with relative...climate combined with the lack of a sustainable research enterprise, there is no easy way for academia ...enterprise in the U.S. will decrease. At Future of Research, we think this is a good thing. Reliance on a ...

...is a component of the immune system useful as a research reagent? Let’s find out! What is an antibody? ...system and a tool that can be used for a variety of research applications. Within the immune system, antibodies...ability of antibodies to bind proteins is useful for research applications as well because they allow scientists...and initiates different immune cascades. In the research setting, antibodies of different isotypes can ...antibodies can recognize. Imagine you’re doing a word search puzzle. You’re not always going to spot the whole...string of letters is a part of the word you’re searching for. Antibodies may recognize a linearized sequence... many ways that antibodies can be produced for research purposes, some of which take advantage of natural...