We narrowed to 303 results for: SPI;

1. Hot Plasmids Spring 2024

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   ...high fidelity during action potentials of fast-spiking neurons. The same A-to-D mutation in the related...

2. Neuronal labeling with Spaghetti Monster

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   ...been used to visualize “thorny excrescence” (TE) spines in the Hippocampal CA3 pyramidal neurons which ...

3. Antibodies 101: Immunoprecipitation

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   ... slightly higher, than those of agarose beads, despite the size difference. Magnetic beads are particularly...

4. Four Base Editing Reporters to Monitor and Enrich Editing in Real-time

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   ...populations. To develop this method the lab was inspired by work that used an integrated GFP reporter that...

5. Plasmids 101: Plasmid Incompatibility

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   ...References  del Solar G, Giraldo R, Ruiz-Echevarría MJ, Espinosa M, Díaz-Orejas R (1998) Replication and Control...

6. Advancing Biology with Zebrafish: Genetic Tools for Developmental Studies and More

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   ...CRISPR/Cas9-mediated insertion of foreign DNA. Despite these caveats, several features of zebrafish—including...

7. Rett Syndrome: A History of Research and Therapeutic Outlooks

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   ...exhibit slow head growth, develop seizures, cardio-respiratory dysfunction, distinctive hand movements, and ...

8. Overcoming the AAV Size Limitation for CRISPR Delivery

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   ...019-0501-5  Liu J-J, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington...

9. Advanced Uses of Cre-lox and Flp-FRT - A Neuroscientist’s View

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   ... Cardin, Jessica A. et al. 2009. “Driving Fast-Spiking Cells Induces Gamma Rhythm and Controls Sensory...

10. Antibiotic Resistance: An Old Solution but a New Problem

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    ...Antibiotic resistance is defined as microbial survival despite exposure to antibiotics designed to kill them or...

11. Changing Labor Laws Bring Increased Postdoc Wages

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    ...salaries at or above $50,000. Boston Children’s Hospital is the only part of the Harvard group that has...

12. The Challenges of Cell Culture

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    ... Crown Publishers, 2010. 2. Gold, Michael. "A conspiracy of cells." State University of New York Press...

13. Avoiding the Dark Side of Fluorescent Protein Fusions with mOX FPs

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    ...for subcellular environment. Currently, she is a SPIRE postdoctoral fellow at the University of North Carolina...

14. Important Considerations in Optogenetics Behavioral Experiments

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    ...science writing. Derek is also a pianist and an aspiring composer. View his blog drsimonsaysscience.org...

15. Data Freedom: The Expansion of Data Sharing in Research Publications

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    ...Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, Canada where he studies protein-serine...

16. 3 Tips to Improve HDR Efficiency for CRISPR Editing in Human Cells

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    ...only saw incorporation of the blocking mutation. Despite the fact that both the blocking mutation and our...

17. Replacing Paper: Tips for Choosing an Electronic lab Notebook

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    ...to insufficient and non-standard record keeping despite scientist’s best efforts. We all have software ...

18. Filming Science Videos in the Age of Social Distancing

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    ...during the middle of lockdown, and some that will spin up real soon. Video production, just like science...

19. Fluorescent Proteins 101: GFP Fusion Proteins - Making the Right Connection

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    ...necessary for post-translational modifications. Despite these potential issues, GFP has been used successfully...

20. Five Popular Model Organisms, Part 2

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    ...regenerate complex structures such as limbs, the spinal cord, and internal organs including the heart, ...