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We narrowed to 967 results for: ARC

Showing: 241 - 260 of 967 results

  1. Summer SciComm Series: Master of SciComm

    Type
    Blog Post
    ...individuals whose research ranged from wildlife conservation to abortion law to poetry. A research discipline...not ultimately translate to a desire to do the research itself. Several years of exclusively writing lab...depicting nuclear fission; a podcast with a genetics researcher on parasitoid wasps; and an essay on the life...versatility in the face of disparate spheres of research. In my case, an interest in neuroscience was carried...occupied my attention, until these coalesced into a research topic on concussion in sport and the public’s ...sport my entire life, I was curious as to what the research had to say. Moreover, this subject allowed me ...public utilizes insights gleaned from scientific research is, after all, one of the enduring goals of science...

  2. Typing CRISPR Systems

    Type
    Blog Post
    ... Overview of the CRISPR classification hierarchy. The hierarchy flows from Class to type to subtype to...a decade of frenzied interest in bacterial and archaeal immune systems. During this time, scientists discovered...perhaps provide insights and ideas for your own research! Classification Structure Principles of CRISPR...fast evolution of these adaptive bacterial and archaeal immune systems has led to extreme sequence divergence...classifications were placed into a fairly simple hierarchy: class to type to subtype to variant. Despite ...seemingly complicated steps to arrive at this hierarchy, the main aspects of each class and type are easy...identified CRISPR-Cas in bacteria and nearly 100% in archaea, though Class 1 remains largely underutilized compared...

  3. CRISPR Plasmids - Drosophila

    Type
    Collection
    ...alleles. To introduce specific genomic changes, researchers use ssDNA or dsDNA repair templates with homology...

  4. CRISPR Plasmids - Yeast

    Type
    Collection
    ...alleles. To introduce specific genomic changes, researchers use ssDNA or dsDNA repair templates with homology...

  6. Fluorescent Protein Travel Awards - FLiPs and Fluorescent Protein Biosensors

    Type
    Blog Post
    ...proteins have enabled scientists to pursue creative research avenues previously unavailable to them. With these...interactions. Beyond these common applications, researchers are finding new ways to apply fluorescent proteins...Roger Tsien played enormous roles in enabling researchers to utilize and develop these tools by making ...fluorescent protein technologies widely available to the research community. To honor their legacy, we recently ...help scientists share their fluorescent protein research with the academic community by funding their travel...demonstrated the utility of these FLiPs in a variety of research applications and particularly notes their ability...inducible enzyme technologies. She hopes that other researchers will be able to use similar designs to create...

  7. How Addgene Creates Content

    Type
    Blog Post
    ...publication.   Do research! Nearly everything we write entails a primary literature search to collect up ...webinars, or use other research methods. In the case of the antibody guide, primary research and previously ...easily and quickly access tools to further their research. However, tools aren’t very useful if you don...goal is to provide informative content to help researchers in creating and sharing knowledge, related to... types of materials we help distribute and the research communities that we serve. How we curate (and...you didn’t know you wanted to know about, like research breakthroughs or cool new tools. And while this... Center, help.addgene.org, where you can easily search articles answering all of our frequently asked ...

  8. A new platform for fast functional characterization of potentially cancerous mutations

    Type
    Blog Post
    ...Addgene.org Find plasmids for your research Find cancer research plasmids and resources ...represents a considerable barrier to furthering research and developing effective treatments for the disease...work, and how these plasmids can help cancer researchers studying an assortment of genes. Using patient...Anderson Cancer Center patient databases, this research team identified 1,049 perturbations in several...the High-Throughput Mutagenesis and Molecular Barcoding (HiTMMoB) technique (Tsang et al., 2016), creating...functional annotation of thousands of mutations The researchers used the collection to screen individual perturbations... platform is an incredible boost to the cancer research community, but what else are these plasmids useful...

  9. mTOR Pathway

    Type
    Collection
    ... Cancer Research mTOR Pathway mTOR Pathway You May Also Like: Cancer...

  10. Hot Plasmids Spring 2024

    Type
    Blog Post
    ...Neurodegeneration Research Collection. This page is regularly updated with useful materials for research into Alzheimer...editor PE7 Antibodies to facilitate SARS-CoV-2 research New viral vector preps of Voltron2 voltage sensors...1: CROPseq-multi uses two sgRNAs with internal barcodes (iBARs), multiplexed using tRNAs, within the lentiviral... team designed sgRNAs that include an internal barcode and separated multiple sgRNAs with tRNAs, which...motif to stabilize the 3’ end of the pegRNA. As research has just begun with PE7, it will be exciting to...38570691. Antibodies to facilitate SARS-CoV-2 research   By Ashley Waldron Ready-to-use recombinant antibodies... the Addgene repository of tools for SAR-CoV-2 research. Two new antibodies, Anti-SARS-CoV-2 Nucleocapsid...

  11. Fostering communication in remote collaborations

    Type
    Blog Post
    ... the progress of research, they can also present hurdles for the team of researchers involved. Communication... where researchers spent time in each other’s labs. This is an opportunity for the researchers involved...Communication is a major challenge when researchers are communicating across disciplines or doing different...or Google Hangouts is a great way to include researchers from different locations. Having virtual face-to-face...best for them. This also accelerates the pace of research by circumventing the slower, sequential communication...document. Set and manage expectations When the researchers involved in a project are scattered across the...future directions of the project. The state of research is constantly shifting, and long-distance collaborations...

  12. Cellosaurus: A Cell Line Information Database

    Type
    Blog Post
    ...describe all cell lines used in research, using four methods to search out cell lines: Periodic surveying...approximately one-third of cell lines used in scientific research are misidentified! Rigor and reproducibility of...collections websites and catalogues Literature searches utilizing Google Scholar alerts and the NCBI LitSuggest..., such as their vaccine production, SARS-CoV-2 research, or adenovirus packaging cell lines dataset collections...was described. Using Cellosaurus Cellosaurus is searchable by cell line name (recommended names and synonyms...You can also use the Cellosaurus STR similarity search tool (CLASTR) to find cells lines similar to your...adjusted based on query, reference, and shared allele search preferences to help you identify proximal lines...

  13. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

    Type
    Blog Post
    ...mission: Accelerate research and discovery by improving access to useful research materials and information...which we promote our mission and work to enable researchers around the world. We take this responsibility... by generating revenue through distribution of research materials. Our small shipping and handling fees...materials shared through Addgene are being used for research purposes and not for a profit motive. We build... we will always look for new ways to serve the research community. Questions? Feel free to reach out to...science and Addgene in our mission to accelerate research with easier sharing and collaboration. Joanne ... Kayla, Kelly, Kory, Kris, Leila, Lianna, Luke, Marcy, Mary, Max, Maya, Meghan, Melina, Meron, Michael...

  14. New and Upcoming Viral Vectors - Spring 2019

    Type
    Blog Post
    ...pAAV.hSyn-FLEX.iGABASnFR.F102G pAAV-Syn-Archon1-KGC-GFP-ER2 pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2] pAAV-FLEX-tdTomato...constitutive (pAAV-Syn-Archon1-KGC-GFP-ER2) and cre-dependent version (pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2]) ...iGABASnFR and its F102G variant in AAV1 at Addgene! Archon1, a voltage sensor AAV Historically, electrical ...brain was measured with implanted electrodes. The Archon1 voltage reporter allows a way to monitor neuronal...imaging. Since it’s illuminated by red/orange light, Archon1 can also be used in conjunction with optogenetic...this membrane-embedding voltage detector. Find Archon1 and its cre-dependent version at Addgene! Fluorescent... viral protocols and videos Find AAVs for your research ...

  15. Treating Muscular Dystrophy with CRISPR Gene Editing

    Type
    Blog Post
    ...Having seen CRISPR’s success in basic research, researchers are eager to apply it in a clinical setting...Find CRISPR Plasmids for Your Research Find Validated gRNAs for Your Research ...preclinical and clinical work. Find Plasmids for Disease Research on Our Special Collections Pages Duchenne muscular... around 30 years of age. Despite the amount of research conducted on DMD, there is still no good treatment...it difficult to deliver via gene therapy, so researchers have set their sights on another approach. Since...oligonucleotide treatment comes with many challenges, researchers have begun to explore genome editing approaches...CRISPR-mediated exon skipping approach in mice, DMD researchers are very excited. This approach may also be applicable...

  16. Science Career Options

    Type
    Blog Post
    ...skills required Research skills The ability to think critically and carry out in-depth research is applicable...career, do your research Once you have identified possible careers, the next step is to research what each ...Epidemiologist Scientific Recruitment Meteorologist Research and Development Healthcare Consulting Lab Manager...Manager Patent Lawyer Science Market Research Statistician   Attention to detail Patience, accuracy...include: Science Reporter Scientific Illustrator Research and Development Scientific Advisor Lab Manager...Before you begin to apply for a job, it is useful to search online job websites to see what requirements or...Once you’ve assessed your skill set and done your research, it’s time to start sending out applications. ...

  17. With Our New Viral Service, We're Taking CRISPR Further!

    Type
    Blog Post
    ... CRISPR technologies available to the academic research community. At Addgene, we’ve helped distribute...provide ready-to-use CRISPR lentiviral preps to researchers across the globe. Why provide CRISPR as virus...proceed to use it for experiments.” - Alex Chavez, researcher at the Wyss Institute for Biologically Inspired...can make lentivirus production frustrating - a researcher can complete an entire lentiviral production ...receiving a pooled gRNA library in plasmid format, a researcher must amplify the library, use next-generation...reagents from Addgene can greatly expedite a researcher's ability to make discoveries." If you ever run...plasmids to create your own lentivirus stocks. Our research scientists have provided their standard lentivirus...

  18. Four Factors that Differentiate the Stem Cell Field

    Type
    Blog Post
    ...focused on translational research is encouraging. Patients are key to the research, but they are also the...observations regarding what makes this group of researchers special: 1. Stem cell scientists care deeply ...Listen to Our Podcast Interview with Stem Cell Researcher Darrell Kotton 2. Stem cell scientists care about... on spinal cord injuries; Jessica Young shared research on stem cells and Alzheimer's Disease; and Kevin...the reason this research is happening. Stem cells scientists have certainly not lost site of that. 3. Stem...acquisition is not a rate-limiting step in stem cell research. People told me they couldn't have done their ... to helping the stem cell community with their research, I think I can speak for Addgene when I say that...

  19. Lucky Thirteen: Guest Contributors of 2023

    Type
    Blog Post
    ...Information DatabaseResearcher: Amos BairochViral Vectors 101: Systemic CapsidsResearchers: Cynthia Arokiaraj...work with Addgenie writers to help share their research, tools, and knowledge. Guest authors The Codon... Benedict Diederich Course-Based Undergraduate Research Experiences (CUREs)Author: Jason PellettieriNew...NEBGCE4All: Making Genetic Code Expansion AccessibleResearcher: Ryan Mehl; Andy KarplusIBEX Knowledgebase...Knowledgebase: A Data Resource for Multiplex Tissue ImagingResearchers: Andrea Radtke, Ziv YanevCellosaurus: A Cell...ShayMultifunctional Neuronal Fibers: Modulation from Gut to BrainResearchers: Atharva Sahasrabudhe; Polina Aniveeka   A...blog this year! Your contributions have helped researchers around the globe find and share knowledge, resources...

  20. Technologies Enabled by NanoLuc® Luciferase

    Type
    Blog Post
    ...statement: Accelerate research and discovery by improving access to useful research materials and information...post was contributed by Kyle Hooper at Promega. Researchers have been sharing plasmids ever since there were...examples of technologies that can accelerate your research. The creation of NanoLuc® Luciferase from a rather... or above 600 nm wavelengths should be used. Researchers often use bioluminescence to overcome these issues...brightness of NLuc has caught the attention of researchers wanting to perform whole-animal imaging, however...leads to spurious activation of the FRET sensor. Researchers have sought to alleviate many of these challenges...also activate the optogenetic accuators. The researchers took a FRET reporter and adapted it into a BRET...
Showing: 241 - 260 of 967 results