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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

In Category

We narrowed to 648 results for: ato

Showing: 241 - 260 of 648 results

  1. An Integrin Antibody Toolkit from IPI

    Type
    Blog Post
    ...subunit. Using these affinity reagents, the investigators inhibited other RGD-binding integrins, individually...for cell adhesion. The results surprised the investigators, challenging the long-held belief that αVβ3 ...events and training courses on technologies and laboratory techniques related to antibody discovery. You...

  2. Harnessing Bacterial Toxins for Allelic Exchange

    Type
    Blog Post
    ...Rhamnose induction relies on the transcriptional activator rhaS. To allow manipulation of bacteria without...synthetic ribosome binding site (using the online calculator from the Salis group) (Espah Borujeni et al.,...mix. Introduction of the strong transcriptional terminator BBa_B1002 (from IGEM) upstream of the MCS to ...

  3. Generating Mouse Models Using CRISPR/Cas9

    Type
    Blog Post
    ...and opened a sequence file. Then I saw it, the chromatogram showing the telltale signs of a mutation introduced....3026 Gurumurthy CB, Takahashi G, Wada K, Miura H, Sato M, Ohtsuka M (2016) GONAD: A Novel CRISPR/Cas9 Genome...10.1038/s41598-018-33408-9 Mizuno N, Mizutani E, Sato H, Kasai M, Ogawa A, Suchy F, Yamaguchi T, Nakauchi...

  4. Finding Your Science Policy Path

    Type
    Blog Post
    ...can manifest via research and data gathering, regulatory efforts, policy implementation, program management...company who decides how they are going pursue regulatory approval for a new product or a well-endowed ...example proposals and consider applying for their accelerator for some hands-on guidance.   Check out my webinar...

  5. With an Eye Towards the Future, We Look Back at the March for Science

    Type
    Blog Post
    ...worried that, because we were speaking out against legislators and because the march had been so well-publicized...Scientific Instrument Maker at Intellectual Ventures Laboratory. Vancouver, BC Canada 49.2827°N 123.1207°W – ...damage promotes cancer. She is also a science communicator, UBC Public Scholar, and a member of the Vancouver...

  7. CRISPR 101 eBook...en español

    Type
    Blog Post
    ...Addgene contracted with a professional scientific translator, L. Denise Roche, to edit the translation. We...  Many thanks to:  Daniel Mejías Sánchez, PhD, translator  Denise Roche, PhD, MD, editor, ldeniseroche@...

  8. 15 Hot Plasmids from 2017

    Type
    Blog Post
    .... While certain cell types, such as principal excitatory cells and glia, have been successfully targeted...’s lab has developed a new AAV approach using regulatory elements that restrict expression to this cell...wild type SOX2 with either a SOX2-VP16 (strong activator) or SOX2-HP1 (strong repressor) fusion protein...

  10. Celebrating the 2024 Nobel Prize in Chemistry

    Type
    Blog Post
    ...structure is strikingly similar to the design model at atomic resolution” (Kuhlman and Dantas et al., 2003). ...). Design of a Novel Globular Protein Fold with Atomic-Level Accuracy. Science, 302(5649), 1364–1368. ...

  11. New Viral Vectors - Spring 2025

    Type
    Blog Post
    ... retrograde serotype, and a dTomato under the control of the E6 regulatory element, which targets it to...

  12. How Exercise Purges Stress and Keeps Depression at Bay

    Type
    Blog Post
    ...Cell demonstrate how PGC-1a1, a transcriptional coactivator induced in skeletal muscle by exercise and endurance...altogether. Their muscles showed an increase in inflammatory cytokines as a result of those mild stressors...

  15. Let There Be LITE Plasmids

    Type
    Blog Post
    ...customizable DNA-binding domains based on transcription-activator-like effectors (TALEs) as anchors for genome engineering...and modular,” Konermann said. “Transcriptional activators are easy to expand or combine with different ...

  16. Editor's Choice, August 2016

    Type
    Blog Post
    ... bit of a Twitter storm surrounding NgAgo, its creator, Han Chunyu of Hebei University of Science and ...Transductions Single Base Editing with CRISPR Cas9 Activators: A Practical Guide 10 Steps to a Perfect Science...

  17. Modulate the Activity of 17 Signaling Pathways with One Kit!

    Type
    Blog Post
    ...environments, for example. “We’ve been contacted by investigators all over the world who are interested to use...researchers have plans to expand the library to include activators for more cancer-related pathways and more nodes...

  18. Inside Addgene's 10 Year Anniversary Gala

    Type
    Blog Post
    ...hour, we feasted on sliders, hot dogs and a mashed potato bar (complete with all the fixings), as well as...about her grandfather’s humble beginnings as an operator of a printing press. Just as her grandfather used...

  20. 9 Tips to Achieve Success in Academia

    Type
    Blog Post
    ...for students, postdocs, and young Principal Investigators (PIs). We've interviewed Addgene depositors ...different ways to succeed – as loner or gregarious;  dictator or laissez-faire; theory or practice; business-like...
Showing: 241 - 260 of 648 results