...genome could lead to the production of replication-competent adenoviruses (RCAs) that would be able to infect...oncolytic rAdV vectors, which are replication-competent adenoviral vectors that can selectively infect...Recombinant adenoviral vectors, although replication incompetent, are human pathogens and have to be handled at...adenovirus (GLAd) free of adenovirus and replication-competent adenovirus (RCA) contaminants . Experimental &...deliver genetic material into cells. Replication-competent adenovirus (RCA) Mutated adenoviral vector that...