We narrowed to 423 results for: NUC

1. Five Popular Model Organisms

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   Blog Post

   ...like those that overexpress the toxic protein α-synuclein (the most common protein found in lewy bodies)...

2. New Optogenetic Tools for Cytoskeleton and Membrane Control

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   Blog Post

   ...by Rho family signaling pathways. Rho guanine-nucleotide exchange factors (GEFs) activate their partner...

3. Multiple Plasmids at a Low Price: Kits from Addgene

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   Blog Post

   ...Choudhury, Rajarshi, et al. "Engineering RNA endonucleases with customized sequence specificities." Nature...

4. Using Phosphoserine to Study Protein Phosphorylation

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   Blog Post

   ...PhosphoSitePlus, 2014: mutations, PTMs and recalibrations." Nucleic acids research 43.D1 (2015): D512-D520. PubMed ...

5. Targeting HIV-1 with CRISPR: Shock and Kill or Cut it Out?

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   Blog Post

   ...this approach doesn’t require a functional Cas9 nuclease, so there’s no potential for aberrant DNA cleavage...

6. Evolution of Brainbow: Using Cre-lox for Multicolor Labeling of Neurons

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   Blog Post

   ...inversion of the construct. Sanes and Lichtman used pronuclear injection to insert these Brainbow constructs...

7. CRISPR Plasmids - gRNAs

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   Collection

   ... sequences designed to be used with any CRISPR nuclease and function. Please see the publication or plasmid...

8. CRISPR Plasmids - Base Edit

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   Collection

   ...editing systems create a wide spectrum of single-nucleotide variants (somatic hypermutation) in a wider editing...

9. Hot Plasmids: Spring 2025

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   Blog Post

   ...2025). In retrotransposon insertion, a combined endonuclease-reverse transcriptase uses homology arms flanking...

10. Antibodies 101: The Basics of Western Blotting

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    Blog Post

    ...compartments such as the mitochondria, cytoplasm and nucleus.  We hope that this blog has provided you with ...

11. Technique: Probe Phage Genomes for Host Binding Proteins

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    Blog Post

    ... in order to protect their DNA from host cell nucleases (4). To further complicate matters, even when ...

12. AAV Molecular Tools

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    Collection

    ...Genome Engineering Tools These AAV encode Cas9 nuclease used in the CRISPR-Cas9 system for targeted genome...

13. Distribution to Industry

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    ...genome editing of human TP53 exon 5–8. Phagemid Synuclein VHH Immune Library Screening Messer and MJFF Created...

14. Mycoplasma Contamination: Where Does It Come From and How to Prevent It

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    Blog Post

    ...result interpretation. Also, the signals from the nuclear area make the detection of mycoplasmas difficult...

15. Quick Guide to All Things Lentivirus

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    Blog Post

    ...LTRs) has been removed, Rev (which facilitates nuclear export) is expressed from a separate plasmid, and...

16. DNA Quantification

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    Protocol

    ...your substance maximally absorbs. In the case of nucleic acid (DNA and RNA), the maximal absorbance is at...Protein maximally absorbs at 280nm and the ratio of nucleic acid to protein (260/280) is generally used as ...

17. Plant Plasmids and Resources

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    Collection

    ...CRISPR/Cas Toolkit for Plants includes CRISPR/Cas nucleases, base editors, gRNA backbones, and promoters for...

18. p53 Pathway

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    ...apoptosis inducing protein 1 p53R2 p53 inducible, ribonucleotide reductase M2 B (RRM2B) PAG608 Zinc finger, ...

19. Lentiviral Prep Service

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    Collection

    ...Genomic Sequences To perform genome edits, Cas9 nuclease is used to generate double-stranded breaks ( DSBs...

20. With an Eye Towards the Future, We Look Back at the March for Science

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    Blog Post

    ... Nicholas Thompson is a PhD Candidate studying Nuclear Science and Engineering at Rensselaer Polytechnic...