Skip to main content
Addgene

Enter a sequence to perform a BLAST-based search of the Addgene plasmid sequence database.

Information

In Category

We narrowed to 165 results for: LOB;

Showing: 21 - 40 of 165 results

  2. Supporting Rare Disease Research with the 2020 BeHEARD Awards

    Type
    Blog Post
    ...Creatine Deficiency Syndromes (CCDS) that present as global developmental delays or autism spectrum disorder...transporter SLC6A8 impede this transport and result in global creatine deficiency, which is characterized by ...estimated to affect 0.27 to 4.6 per 10,000 people globally. Pustules form from the uncontrolled activation...

  3. CRISPR in the Clinic

    Type
    Blog Post
    ...involved turning on fetal hemoglobin to compensate for defects in the adult hemoglobin produced (Zarghamian... beta thalassemia (TBT), both of which affect hemoglobin. Most of the targeted treatment strategies for...

  4. COVID-19 Resources

    Type
    Collection
    ...COVID-19 and Coronavirus Plasmids & Resources The global research community is moving quickly to expand ... (CD147), transmembrane glycoprotein of the immunoglobulin superfamily, binds to the SARS-CoV-2 S protein...

  5. The Effect of COVID-19 on Liu Lab Plasmid Requests From Addgene Data

    Type
    Blog Post
    ...lab plasmid requests from Addgene, as a proxy for global activity in our particular scientific subfields...smoothed with a 7-day rolling mean. While this global approximation already shows us a rough "COVID-19...modeling our data, we first chose to re-examine our global data at a finer temporal granularity. For each ...

  6. Rett Syndrome

    Type
    Collection
    ...affect disease severity. The MECP2 protein is a global transcriptional regulator of thousands of genes... to regulate gene expression either locally or globally. The MECP2 protein contains several functional...

  7. Plasmids 101: Broad Host Range Plasmids

    Type
    Blog Post
    ...braziliense, Azotobacter spp., Bordetella spp., Caulobacter spp., Enterobacteriaceae, Gluconacetobacter xylinus...Azotobacter vinelandii, Brevibacterium methylicum, Caulobacter crescentus, Desulfovibrio vulgaris, Erwinia carotovora...bacilliformis, Bordetella spp., Brucella spp., Caulobacter crescentus, Escherichia coli, Gluconacetobacter...

  8. Caltech Systemic Capsids

    Type
    Collection
    ... CN1390-rAAV-DLX2.0-minBG-SYFP2-WPRE3-BGHpA minBetaGlobin SYFP2 Control Ting 163509 CN1839-rAAV-hSyn1-...recombinase iFlpV Zeng 164450 CN1851-rAAV-hI56i-minBglobin-iCre-4X2C-WPRE3-BGHpA minBG iCre expression iCre...

  9. Quick Guide to Near-Infrared Fluorescent Proteins

    Type
    Blog Post
    ... coding for heme oxygenase should be supplied (Baloban et al., 2017).  It is important to consider effective...Cells. Cell Chem Biol 24, 758-766 e753 (2017). Baloban, M. et al. Designing brighter near-infrared fluorescent...Science 8, 4546-4557 (2017). Shcherbakova, D.M., Baloban, M. & Verkhusha, V.V. Near-infrared fluorescent...

  10. 28 Hot Plasmid Technologies from 2015

    Type
    Blog Post
    .../ARE). The Luc-I intron is a chimeric β-globin/immunoglobulin intron that has been commonly used in constitutive...nuclease domain. Feng Zhang's group utilized the bi-lobed architecture of Cas9 to engineer a series of "split...filter out any compounds that are affecting other global cell processes, like translation. This luciferase...hours) in order to avoid complicating effects from global toxicity due to loss of splicing. To this end, ...

  11. Antibodies 101: Introduction to Antibodies

    Type
    Blog Post
    ... is an antibody? Antibodies, also known as immunoglobulins, are ~150 kDa, Y-shaped proteins that are both..., and the Fc, or crystallizable region. Two immunoglobulin (Ig) heavy chains and two Ig light chains make...antibodies, which come from naturally-occurring immunoglobulin genes, recombinant antibodies are plasmid-based...

  12. Trends in CRISPR and SynBio Technologies

    Type
    Blog Post
    ...distirbution for these fast moving fields.  Addgene is a global nonprofit plasmid repository. Over 2,000 labs have... presented a poster with data comparing Addgene global deposit and distribution trends for Zinc Finger...

  13. CRISPR 101 eBook...en español

    Type
    Blog Post
    ... todo el mundo para ayudar a aumentar el acceso global a los materiales de nuestro repositorio. Este increíble... distributors across the world to help increase global access to materials in our repository. This incredible...

  14. Depositor Week 2020 is Happening Now. Join us!

    Type
    Blog Post
    ...19 reagents available to researchers across the globe very quickly. There are over 2,300 COVID-19 related...grasp the big impacts depositors have on science globally. *All data presented in this blog post includes...

  15. Reflections and Looking Ahead

    Type
    Blog Post
    ... us understand how Addgene can better serve the global scientific community. As we enter 2025, your feedback...expanding educational resources, and our commitment to global accessibility, we're equipping every scientist ...

  16. 2023 and 2024: Reflections and Looking Ahead

    Type
    Blog Post
    ...countries, into our repository, while expanding global access to our repository through our distributor..., we will be actively seeking ways to support a global community where every researcher feels both welcomed...

  17. Bringing Sustainable Practices to the Lab: Recycling

    Type
    Blog Post
    ...s population, we account for an estimated 2% of global plastic generation. Less than 9% of plastics are...changes in the lab could make a big difference in our global impact as scientists. Many scientists are already...

  18. Fostering communication in remote collaborations

    Type
    Blog Post
    ...Science is a global endeavor, and that can often mean that scientists who live across the country or ... involved in a project are scattered across the globe, it can be easy to get preoccupied with other work...
Showing: 21 - 40 of 165 results