Adeno-associated virus (AAV) Guide
Type
Guide
...contains a Gateway cassette containing the ccdB gene, a ccdB-resistant strain is necessary. For more information...capacity for long-term gene expression. These features make them ideal for gene therapy, neuroscience ...biomedical fields. Gene Therapy One of the major applications of rAAV vectors is in the field of gene therapy to...virus (AAV) as novel vectors for human gene therapy . Current Gene Therapy, 3 (4), 281–304. https://doi....the two ITRs with a gene expression cassette that typically contains the transgene of interest. The size...vectors to deliver genes to cells in in vivo models. For more detailed protocols, see Addgene’s Viral Vector...host genome can have on transgene expression and the expression of neighboring genes. rAAV episomes can develop...