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An all-in-one CRISPR/Cas9 Multiplex Genome Engineering System for transfecting and editing cell lines.

An overview of CRISPR's development from a prokaryotic immune system to a valuable genome engineering tool.

Learn how the Personal Genetics Education Project (pgEd) engages with various communities on biological science and technology. Get tips on how to work at a similar organization from pgEd's director of new initiatives, Johnny Kung.

Find tips and best practices for producing lentivirus in your lab: from choosing a packaging system to optimizing transfection and improving titers.

A look at the challenges facing the field of plant synthetic biology, including a discussion of changing public perception, IP concerns, and more.

Antibody data repositories and search engines can help you find the right antibody for your experiment. Check out a list of helpful links to get you started.

Play along in the scavenger hunt to find Addgene pets all over the blog. Enter to win Addgene swag!

Take a look at the developments in genome engineering throughout history and the parallels in science fiction.

Learn about antibody engineering, including what it is and why we like it. Deep dive into antibody directed evolution techniques, and learn about Addgene's partnership with the Institute for Protein Innovation (IPI).

Addgene is excited to announce its very first AAV Data Hub Challenge.

Master the streak plate technique using a mixture of E. coli strains expressing a different chromoprotein.

Learn about the common techniques to creating engineered mouse models at embryonic stages and the pros and cons of different genome editing techniques.

Learn about xCas9, an engineering Cas9 variant with broad PAM flexibility and high on-target specificity.

Resources to help improve precision genome editing through homology directed repair in experiments with CRISPR nucleases.

GreenGate is a cloning system for rapidly assembling plant transformation constructs and is based on the Golden Gate method.

New England Biolabs has deposited plasmids at Addgene to generate SNAP, CLIP, ACP or MCP tagged plasmids for visualization of proteins inside cells.

Learn about what's coming for Addgene in 2026

INTEGRATE is a bacterial genome engineering system that uses CRISPR to direct transposition to targeted locations in the genome.

Get a behind-the-scenes look at Addgene's new search engine.

Browse the Zhang lab’s comprehensive human transcription factor collection, available at Addgene. The collection can be used for screening transcription factors for cellular programming or cancer drug resistance.