We narrowed to 724 results for: ACE

1. Developing a cold tolerant E. coli using specialized chaperones

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   ...legends who not only survive, but thrive, in the face of some of Earth’s harshest environments: corrosive...out rapidly in warm weather. Psychrophilic enzymes face very similar issues when forced to express in mesophilic...

2. Behind the scenes: Addgene’s new search engine and more

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   ...information, however, did not improve at the same pace as the quantity and quality of the information. ...down, and zooming out — with an intuitive user interface.   The team approached the issue from multiple...

3. 7 Tips to Secure a STEAM Internship This Summer

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   ...endeavor. Due to the COVID-19 pandemic, students will face a reduced supply of internships as a result of the...narrative that is positive, and forward-looking. Embrace it, and let your personality leap out of the page...

4. Sweating the Small Stuff: Details in the Lab

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   ...adjustments in the physical organization of your workspace and your workflow can have a huge impact. Test... experiments at odd hours, used more secluded workspaces, or politely asked to not be disturbed when they...

5. Communicating Your Science With Help From ComSciCon

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   ...annual flagship workshop.  Our 2018 workshop took place in Boston - you can revisit the activities of our...get in touch with ComSciCon, find us on Twitter, Facebook, Instragram, or send an email to [email protected]...

6. A Deep Dive into BioBuilder

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   ...focused on an emerging scientific field, BioBuilder embraces new opportunities for scientific exploration, ... opened in August 2017.  This flexible teaching space offers STEM programming, workshops, and customized...

7. Will You Be My Mentor? Finding and Asking for Mentoring Support

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   ...outside your organization. The mentor in your own workplace is able to: Help you identify specific skills...can tap for email discussions. It is also a great place to practice your mentoring skills. Online mentoring...

8. Viral Vectors 101: An Introduction to AAV

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   ...in recombinant AAVs (rAAVs) with maximum “trunk” space for genetic cargo. Typically, when researchers speak...dependent switches control gene expression via switches placed in your cell type of interest. Careful combination...

9. CRISPR 101: Cas9 vs. The Other Cas(s)

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   ... RNA editing. Fast facts – PAM requirement: protospacer flanking sequence – A, U, or C. Best for: targeting...development and use. Fast facts – PAM requirement: protospacer flanking sequence – none. Best for: targeting...

10. Transferable Skills Guide: Cross-team Communication

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    ...communication, be it in your academic lab or your workplace, is an ongoing process. It is never really done...you try any of these approaches in your lab or workplace, let me know. If you have come upon any other ...

11. Reproducibility for Everyone: Lessons from an Open Science Collaboration

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    ...collaboration. The first iteration of these workshops took place at Caltech in Jan 2018 and involved presentations...dedicated website to host all the materials in one place and better serve researchers at all levels of the...

12. Transferable Skills Guide: Problem Solving

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    ...entails will help keep you motivated when you’re faced with yet another hurdle in your research journey...will always be room to improve. The next time you face a problem, try to be mindful of how you work through...

13. Channelrhodopsins with improved light sensitivity for minimally-invasive optogenetics

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    ...Figure 1). This light-induced excitation can take place in a tissue culture dish but can also happen in ... motor cortex (M2). Since M2 is located on the surface of the brain, to deliver light to the channelrhodopsin-expressing...

14. Supporting Rare Disease Research with the 2020 BeHEARD Awards

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    ...understand so that we could possibly develop pharmaceutical interventions that would inhibit IL-36 release...intensity-based signaling biosensors to monitor intracellular signaling,” says Hébert. Previous research has...

15. Summer SciComm: Preprints

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    ... et al. (2018). Of course, preprints don’t replace journals and other modes of scientific communication...journal and share it more widely!  Not everyone embraces preprints as part of their scientific communication...

16. Choosing the B(right)est Fluorescent Protein: Aggregation Tendency

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    ... on size is ultracentrifugation. Sedimentation equilibrium analytical ultracentrifugation yields an affinity...

17. Plasmids 101: The Wide World of Natural Plasmids

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    ...developed to replace helper viruses in AAV production systems. We’re just skimming the surface of the natural...

18. Pathways Over Time Plasmids Engage Students in Functional Genomics Research

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    ... to undergraduate students (1, 2), but educators face significant challenges in designing suitable projects...complementation should only occur when galactose replaces glucose as the carbon source. Student results ...

19. Synthetic promoter AAVs for cell-type specific expression in retinal cells

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    ... specific transcription factor binding sites interspaced with random sequences.   Strategy #4 (ProD): ...where lower levels of labeling makes it easier to trace a neuron’s projections. Generating animal models...

20. A Look Back at One Year of Plasmid Sharing for COVID-19 Research

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    ...SARS-CoV-2 virus depends on its spike protein to bind ACE2, the host cellular receptor. To more easily study...SARS outbreak, Hyeryun Choe’s lab identified that ACE2 is the functional receptor for SARS-CoV. The lab...