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We narrowed to 969 results for: ARC;

Showing: 201 - 210 of 969 results
  1. When Fidelity Matters: A frank discussion about ligase fidelity

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    Blog Post
    ... by guest blogger Greg Lohman, a biochemistry researcher at New England Biolabs. When do you need a high...high-throughput profiling New England Biolabs® (NEB) researchers recently published a method for the high-throughput...blogger, Greg Lohman! Greg Lohman is a biochemistry researcher at New England Biolabs, specializing in the enzymology...Thermus thermophilus DNA ligase." Nucleic acids research 24.15 (1996): 3079-3085. PubMed PMID: 8760897....in duplex DNA by T4 DNA ligase." Nucleic acids research 10.5 (1982): 1425-1437. PubMed PMID: 7041091. ...can be sealed by T4 DNA ligase." Nucleic acids research 15.21 (1987): 8755-8771. PubMed PMID: 3684572....mononucleotide repeat sequences." Nucleic acids research 27.24 (1999): e40-e47. PubMed PMID: 10572192. ...
  2. How to Write a Scientific Review Article

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    Blog Post
    ...idea of the themes in the field, I searched for recent research papers on these particular themes, for... your ability to write, to read efficiently, to search the literature, and to synthesize a large volume...particular topic. Alternatively, maybe you’re researching a topic for which no relevant or recent review... the field you plan to review. If it’s a well-researched field, you may need to get specific to make sure... has the benefit of exposing you to relevant researchers in the field. Finally, you can sound credible...an expert in the field. To find reviews, I just searched online and found ones that I thought “looked good...cared about. I also used reviews to get a list of research papers that I needed to read. Once I had an idea...
  3. Safe Port in a Storm...How Addgene is Weathering the Pandemic

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    Blog Post
    ...distribution of plasmids for COVID-19 research is accelerating essential research in laboratories all around the...sometimes wonder if we can take another blow. Back in March, we never expected to be in this here and now. Our...Here's the message I shared with the Addgenies on March 11, 2020 after rumors spread in our building that...scientists around the world mobilized on COVID-19 research, cures, and diagnostics. Almost immediately we...proud of the work we’ve done to support COVID-19 research. Our collection of available materials is growing...the crucial role Addgene plays in accelerating research. Yet this was still not enough to ensure we could... doing almost every type of biomedical science research. Our work accelerates and enhances productive ...
  4. Addgene Receives NIH BRAIN Initiative Grant to Create Open-Access Recombinant Antibody Resource

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    Blog Post
    ...and an inability to improve upon these critical research tools. Addgene is excited to announce that we ...problem.The grant, which is part of the NIH’s Brain Research through Advancing Innovative Neurotechnologies...high-quality antibodies/nanobodies for neuroscience research and is an expert at validating these tools. While...offer numerous advantages, including more secure archiving, unambiguous molecular definition, and potential...the most commonly used reagents in neuroscience research today, but there is a critical unmet need for ...financially self-sustaining through distributions of research materials, such as plasmids and viral vectors....acquisition of affinity reagents and will enable researchers everywhere.” The timing is ideal as the NIH’...
  5. Summer SciComm Series: Master of SciComm

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    Blog Post
    ...individuals whose research ranged from wildlife conservation to abortion law to poetry. A research discipline...not ultimately translate to a desire to do the research itself. Several years of exclusively writing lab...depicting nuclear fission; a podcast with a genetics researcher on parasitoid wasps; and an essay on the life...versatility in the face of disparate spheres of research. In my case, an interest in neuroscience was carried...occupied my attention, until these coalesced into a research topic on concussion in sport and the public’s ...sport my entire life, I was curious as to what the research had to say. Moreover, this subject allowed me ...public utilizes insights gleaned from scientific research is, after all, one of the enduring goals of science...
  6. Typing CRISPR Systems

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    Blog Post
    ... Overview of the CRISPR classification hierarchy. The hierarchy flows from Class to type to subtype to...a decade of frenzied interest in bacterial and archaeal immune systems. During this time, scientists discovered...perhaps provide insights and ideas for your own research! Classification Structure Principles of CRISPR...fast evolution of these adaptive bacterial and archaeal immune systems has led to extreme sequence divergence...classifications were placed into a fairly simple hierarchy: class to type to subtype to variant. Despite ...seemingly complicated steps to arrive at this hierarchy, the main aspects of each class and type are easy...identified CRISPR-Cas in bacteria and nearly 100% in archaea, though Class 1 remains largely underutilized compared...
  7. Fluorescent Protein Travel Awards - FLiPs and Fluorescent Protein Biosensors

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    Blog Post
    ...proteins have enabled scientists to pursue creative research avenues previously unavailable to them. With these...interactions. Beyond these common applications, researchers are finding new ways to apply fluorescent proteins...Roger Tsien played enormous roles in enabling researchers to utilize and develop these tools by making ...fluorescent protein technologies widely available to the research community. To honor their legacy, we recently ...help scientists share their fluorescent protein research with the academic community by funding their travel...demonstrated the utility of these FLiPs in a variety of research applications and particularly notes their ability...inducible enzyme technologies. She hopes that other researchers will be able to use similar designs to create...
  8. How Addgene Creates Content

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    Blog Post
    ...publication.   Do research! Nearly everything we write entails a primary literature search to collect up ...webinars, or use other research methods. In the case of the antibody guide, primary research and previously ...easily and quickly access tools to further their research. However, tools aren’t very useful if you don...goal is to provide informative content to help researchers in creating and sharing knowledge, related to... types of materials we help distribute and the research communities that we serve. How we curate (and...you didn’t know you wanted to know about, like research breakthroughs or cool new tools. And while this... Center, help.addgene.org, where you can easily search articles answering all of our frequently asked ...
  9. Bacterial Expression Systems

    Type
    Collection
    ...replicate plasmids of all types, but beyond that, researchers also use bacteria as model systems to answer ...Addgene distributes many plasmids that can help researchers plan their experiments using bacterial expression...
  10. A new platform for fast functional characterization of potentially cancerous mutations

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    Blog Post
    ...Addgene.org Find plasmids for your research Find cancer research plasmids and resources ...represents a considerable barrier to furthering research and developing effective treatments for the disease...work, and how these plasmids can help cancer researchers studying an assortment of genes. Using patient...Anderson Cancer Center patient databases, this research team identified 1,049 perturbations in several...the High-Throughput Mutagenesis and Molecular Barcoding (HiTMMoB) technique (Tsang et al., 2016), creating...functional annotation of thousands of mutations The researchers used the collection to screen individual perturbations... platform is an incredible boost to the cancer research community, but what else are these plasmids useful...
Showing: 201 - 210 of 969 results