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We narrowed to 969 results for: ARC;

Showing: 231 - 240 of 969 results
  1. CRISPR Activation: A Practical Guide

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    Blog Post
    ...contributed by guest bloggers Marcelle Tuttle and Alex Chavez, researchers at the Wyss Institute for Biologically... thanks to our guest bloggers Marcelle Tuttle and Alex Chavez! Marcelle Tuttle is a medical student at...domain (Fig 1). Two ways to use CRISPRa for your research CRISPRa for specific gene targets CRISPR activation...scale of activation allows for exploratory-based research as well. For example, CRISPRa can be used to find... at Tufts University and former researcher at the Wyss Institute for Biologically Inspired Engineering...Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H,...Zetsche B, Volz SE, Zhang F (2015) A split-Cas9 architecture for inducible genome editing and transcription...
  2. Same Addgene, New Look - Why We Redesigned Our Homepage & Mascot

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    Blog Post
    ...  Easily search for plasmids (and more!) The main goal for the homepage was to improve search and browse...redesign, the new search bar is now front and center, with a clear call to action - Search! Along with this...It became clear to us that we needed to improve search and navigation, while also updating brand messaging...Community, sharing, and fun Along with improving search and navigation, we also wanted to emphasize the...the Addgene blog Learn more about Addgene's new search tool Read more about other features of Addgene'...website Resources on Addgene.org Try out the new search on Addgene's homepage ...
  3. Five Questions to Ask If You're Deciding Between a Master's or PhD Program

    Type
    Blog Post
    ...your favorite search term, i.e. “biology + masters.” For lab-based roles, look for “research associate,”...have masters by using the search term “master’s degree.” Use the LinkedIn search filters to limit results...postings  Look at master’s-level job postings on a job search website like Indeed. Do the job descriptions sound...manuscript and grant preparation, and lead your own research project.  3. Do you prefer being a generalist?...variety of projects and in different fields of research is one of the best parts of my career with a master...master’s. While it's possible to change fields of research with a PhD, a master’s is less specialized so ...
  4. ReFigure: Save Scientific Figures into Dashboards and Share Your Insights

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    Blog Post
    ...in full-length publications. As early career researchers, we wondered how we could make the insights gained...around reading through entire papers, perhaps you search google images for specific experimental results...These data are valuable but remain hidden from research papers as they are not included in traditional...study with multiple patients was published, Zika researcher Christa Osuna collated Zika case studies, making... the NIH and Wellcome Trust now accept interim research products (pre-registration, preprints, data, software...micropublications) in grant proposals. ReFigures are one such research product which can convince reviewers of your expertise...recommend sharing ReFigures on your Linkedin and ResearchGate profile. To see how to create ReFigures in a...
  5. Adeno-associated Viruses (AAVs) for Genome Editing

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    Blog Post
    ...mechanism of incorporation is not well understood, researchers have been using AAV vectors for gene editing ...iPSCs from ~0.2% to ~1.5%. In more recent work, researchers have combined AAVs with CRISPR systems. Ohmori...an AAV’s ~4.5 kB packaging capacity. Luckily, researchers have devised methods to deliver CRISPR components...delivery method frees up space in the AAV allowing a researcher to fill it with the repair template. Bok and ...hematopoietic stem cells respectively. Future researchers could apply this technique to efficiently deliver... continue to use and develop AAVs for your own research and encourage to deposit any new AAV tools you...Cancer Center, Georgetown School of Medicine. His research currently focuses on determining the mechanisms...
  6. Antibody Neutralization Response Against Pseudoviruses Expressing SARS-CoV-2 Spike Protein Variants

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    Blog Post
    ...10.1016/j.cell.2020.12.015 Garcia-Beltran WF, Lam EC, St. Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman...current vaccines differed depending on the variants (Garcia-Beltran et al., 2021). Antibodies from individuals...the P.1 and B.1.351 variants tested. Image from Garcia-Beltran et al., 2021 with permission.   The...quantified in terms of luminescence. Image from Garcia-Beltran et al., 2021 with permission.   Mutations...sera with various pseudotyped virus. Image from Garcia-Beltran et al., 2021 with permission.   Difference...plasmids at Addgene to accelerate ongoing COVID-19 research. “I hope that by sharing the plasmids other scientists...146. https://doi.org/10.1038/s41586-021-03471-w Garcia-Beltran WF, Lam EC, Astudillo MG, Yang D, Miller...
  7. 10 Great Guest Posts We're Thankful For

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    Blog Post
    ...Fluorophores In this post, Luke Lavis from Janelia Research Campus reminds us that, although fluorescent proteins.... To learn how you can use minigenomes in your research, check out this post! R Bodies: Membrane-Rupturing... post, Jessica Polka, formerly a postdoctoral researcher in the Silver Lab at Harvard University, describes...CombiGEM is a technology that can be used to quickly barcode a set of DNA sequences. In this post, Alan Wong... Lab at MIT) shows how you can use CombiGEM to barcode small libraries of CRISPR gRNAs to use for screening...Genome Editing CRISPR has revolutionized how researchers make knockouts and other types of genome edits...In this post, Chris Richardson, a postdoctoral researcher in Jacob Corn’s lab, describes how you can better...
  8. The MTA at Addgene

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    Blog Post
    ...agreement that states the terms of use for a tangible research material that is shared between two parties. There... for organizations to make policy decisions on research use agreements. The UBMTA, which is the MTA most...well-understood and accepted by the majority of research institutes.  Pro tip! In most academic and nonprofit...Transfer department is responsible for managing research use agreements like MTAs.  Addgene does a lot ...plasmids at Addgene are shared under the UBMTA, researchers additionally have the option of distributing ...which allows the plasmids to be distributed for research use only to industry-based scientists. Some organizations...OpenMTA, which allows plasmids to be used for both research and commercial purposes. It’s important to note...
  9. FPbase: A new community-editable fluorescent protein database

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    Blog Post
    ...database is to browse or search information in more powerful ways, and the advanced search page simplifies the...contributed by guest blogger Talley Lambert, a Research Associate at Harvard Medical School. The need ... most indispensable tools in modern biological research.  Any microscopist will tell you that selection...has been very useful over the years, and when researchers come to us for advice on choosing a protein, ...particular FP; this can be done directly using the search bar on the homepage (and at the top of all pages...the process of building advanced multi-parametric search queries.  Looking for a bright, monomeric FP published...guest blogger Talley Lambert! Talley Lambert is a Research Associate at Harvard Medical School. He manages...
  10. Synthesized by Ginkgo Bioworks, Shared by Addgene: SARS-CoV-2 Plasmids for Many Expression Systems

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    Blog Post
    ... results helps other researchers using these plasmids and will give your research more visibility.    ...By Will Arnold and Shreya Vedantam Accelerating research by improving the availability of materials is ...to help academic and industrial labs accelerate research and to help find a faster solution to the COVID...coli and S. cerevisiae expression vectors in late March. The first set of 383 constructs went online just...samples, the rest will be put into a status we call “Archived.” This status allows us to store plasmids and ... is indeed global. Helping scientists speed up research is what we’re here for and we’re glad to be able...Ginkgo Bioworks  Find COVID-19 plasmids for your research Browse the Ginkgo Bioworks COVID-19 Plasmid Collection...
Showing: 231 - 240 of 969 results